专利检索 ap:("ILIAS BIOLOGICS INC.") AND inv:"Nambin Yim" 第 1 页

1.

发明公开
Compositions Containing Protein Loaded Exosome and Methods for Preparing and Delivering the Same 审中-公开

公开(公告)号：US20240075100A1

公开(公告)日：2024-03-07

申请号：US18506575

申请日：2023-11-10

申请人： ILIAS BIOLOGICS INC.

发明人： Chulhee Choi , Nambin Yim , Won Do Heo , Seung-Wook Ryu , Hojun Choi , Kyungsun Choi

IPC分类号： A61K38/17 , A61K47/69 , C07K14/705 , C07K16/18 , C07K16/28 , C12N15/62 , C12N15/85 , C12P21/02

CPC分类号： A61K38/177 , A61K47/6917 , C07K14/705 , C07K14/70596 , C07K16/18 , C07K16/28 , C12N15/62 , C12N15/85 , C12P21/02 , A61K38/00 , C07K2317/80 , C07K2319/03 , C07K2319/70

摘要： The present invention relates to a method for the mass-production of exosome comprising a cargo protein, a vector for preparing the exosome, exosome including a cargo protein prepared by the method, and a method for loading the cargo protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a cargo protein provided by the present invention, the exosome loaded with a cargo protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.

2.

发明授权
Compositions containing protein loaded exosome and methods for preparing and delivering the same 有权

公开(公告)号：US11872193B2

公开(公告)日：2024-01-16

申请号：US16887029

申请日：2020-05-29

申请人： ILIAS BIOLOGICS INC.

发明人： Chulhee Choi , Nambin Yim , Won Do Heo , Seung-Wook Ryu , Hojun Choi , Kyungsun Choi

IPC分类号： C12N15/62 , C12N15/85 , A61K47/69 , A61K38/17 , C07K16/28 , C12P21/02 , C07K16/18 , C07K14/705 , A61K38/00

CPC分类号： A61K38/177 , A61K47/6917 , C07K14/705 , C07K14/70596 , C07K16/18 , C07K16/28 , C12N15/62 , C12N15/85 , C12P21/02 , A61K38/00 , C07K2317/80 , C07K2319/03 , C07K2319/70

摘要： The present invention relates to a method for the mass-production of exosome comprising a cargo protein, a vector for preparing the exosome, exosome including a cargo protein prepared by the method, and a method for loading the cargo protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a cargo protein provided by the present invention, the exosome loaded with a cargo protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.