公开(公告)号：US20250004002A1

公开(公告)日：2025-01-02

申请号：US18759367

申请日：2024-06-28

Applicant: ILLUMINA, INC.

Inventor： Richard Lemoine ,  Jason Oh ,  Jacob Ruden ,  Xiangxiong Chen ,  James Osmus ,  Andrew Enslow ,  Steven Hendrix

IPC: G01N35/04 ,  B01L3/00

Abstract: Systems and related reagent cartridge queuing methods are disclosed. In accordance with an implementation, an apparatus includes a first reagent cartridge, a second reagent cartridge, and a system. The system includes a sipper manifold assembly having a sipper, a queue to carry the first reagent cartridge and the second reagent cartridge, a cartridge moving assembly, and a cartridge receptacle assembly. The cartridge moving assembly includes a gantry, a carriage actuator, and a carriage. The carriage is coupled to the gantry and the carriage actuator is to move the carriage relative to the gantry. The cartridge receptacle assembly has a cartridge receptacle to receive the first reagent cartridge or the second reagent cartridge. The carriage is to move the first reagent cartridge from the queue and position the first reagent cartridge into the cartridge receptacle.

公开(公告)号：US20230356230A1

公开(公告)日：2023-11-09

申请号：US18002448

申请日：2022-03-02

Applicant: ILLUMINA, INC. ,  ILLUMINA CAMBRIDGE LIMITED

Inventor： Elisabet Rosas ,  Philip Balding ,  Cyril Delattre ,  Jacqueline Weir ,  Ramir Vega ,  Jennifer Foley ,  Paul Sangiorgio ,  Darren Segale ,  Pietro Gatti Lafranconi ,  Tarun Khurana ,  Jacob Ruden ,  Craig Hetherington

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/1861 ,  B01L2300/1894

Abstract: Reagent cartridges and related systems and methods for controlling reagent temperature are disclosed. In accordance with an implementation, an apparatus includes a system and a reagent cartridge. The system includes a reagent cartridge receptacle, a non-contact temperature controller, a processor operatively coupled to the temperature controller. The reagent cartridge is receivable within the reagent cartridge receptacle and includes a flow cell assembly, a plurality of reagent reservoirs, and a manifold assembly. The manifold assembly includes a common fluidic line and a plurality of reagent fluidic lines. Each of the plurality of reagent fluidic lines is adapted to be fluidically coupled to a corresponding reagent reservoir and selectively couplable to the common fluidic line. The processor is to cause the temperature controller to change a temperature of at least one of the common fluidic line or one or more of the reagent fluidic lines.