公开(公告)号：US12011000B2

公开(公告)日：2024-06-18

申请号：US18346437

申请日：2023-07-03

申请人： IMPETUS AGRICULTURE, INC.

发明人： Heba Mohamed Yassen Abdelgaffar ,  Constanze Hahnfeld ,  Juan Luis Jurat-Fuentes ,  Erik Jongedijk ,  Jeffrey M. Staub ,  Stefan Meldau

IPC分类号： A01N63/50 ,  A01P7/04 ,  C07K14/325 ,  C07K16/12 ,  C07K16/28

CPC分类号： A01N63/50 ,  A01P7/04 ,  C07K14/325 ,  C07K16/1278 ,  C07K16/28 ,  C07K2317/31 ,  C07K2317/569 ,  C07K2317/92 ,  C07K2319/55

摘要： Affinity constructs and affinity molecules to direct insecticidal toxins to insect specific structures of target insects are presented herein. The affinity constructs comprise of at least one affinity molecule that is capable of recognizing, or capable of binding to, or binding to, or being directed to, or being designed to bind to an insect-specific structure in and/or on a target insect, and at least one other affinity molecule capable of binding to, or binding to, or being directed to, or being designed to bind to an insecticidal protein (toxin) wherein the at least two affinity molecules are operably coupled. Presented herein are also methods of making and using these affinity constructs and affinity molecules.