公开(公告)号：US20240349732A1

公开(公告)日：2024-10-24

申请号：US18637092

申请日：2024-04-16

申请人： IMPETUS AGRICULTURE, INC.

发明人： Heba Mohamed Yassen ABDELGAFFAR ,  Constanze HAHNFELD ,  Juan Luis JURAT-FUENTES ,  Erik JONGEDIJK ,  JEFFREY M. STAUB ,  Stefan MELDAU

IPC分类号： A01N63/50 ,  A01P7/04 ,  C07K14/325 ,  C07K16/12 ,  C07K16/18 ,  C07K16/28

CPC分类号： A01N63/50 ,  A01P7/04 ,  C07K14/325 ,  C07K16/1278 ,  C07K16/18 ,  C07K16/28 ,  C07K2317/22 ,  C07K2317/31 ,  C07K2317/569 ,  C07K2317/92 ,  C07K2319/55

摘要： Affinity constructs and affinity molecules to direct insecticidal toxins to insect specific structures of target insects are presented herein. The affinity constructs comprise of at least one affinity molecule that is capable of recognizing, or capable of binding to, or binding to, or being directed to, or being designed to bind to an insect-specific structure in and/or on a target insect, and at least one other affinity molecule capable of binding to, or binding to, or being directed to, or being designed to bind to an insecticidal protein (toxin) wherein the at least two affinity molecules are operably coupled. Presented herein are also methods of making and using these affinity constructs and affinity molecules.

公开(公告)号：US20240262872A1

公开(公告)日：2024-08-08

申请号：US18595330

申请日：2024-03-04

申请人： Monsanto Technology LLC

发明人： James A. Baum ,  Artem G. Evdokimov ,  Stanislaw Flasinski ,  Farhad Moshiri ,  Timothy J. Rydel ,  Eric J. Sturman ,  Moritz von Rechenberg ,  Halong Vu ,  Andrew M. Wollacott ,  Meiying Zheng

IPC分类号： C07K14/325 ,  A01N37/46 ,  C07K14/00 ,  C07K14/32 ,  C07K14/435 ,  C12N15/82

CPC分类号： C07K14/325 ,  A01N37/46 ,  C07K14/001 ,  C07K14/32 ,  C07K14/43577 ,  C12N15/8286 ,  Y02A40/146

摘要： The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.

公开(公告)号：US20240196906A1

公开(公告)日：2024-06-20

申请号：US18555429

申请日：2022-04-14

申请人： Invaio Sciences, Inc.

发明人： Maier Steve AVENDAÑO AMADO ,  Rama Krishna SIMHADRI ,  Duane Lee KRISTENSEN ,  James Aaron KRAEMER

IPC分类号： A01N63/22 ,  A01N25/02 ,  C07K14/325 ,  C12N1/20 ,  C12R1/125 ,  C12R1/19

CPC分类号： A01N63/22 ,  A01N25/02 ,  C07K14/325 ,  C12N1/20 ,  C12R2001/125 ,  C12R2001/19

摘要： This disclosure provides pesticidal minicells, compositions including pesticidal minicells, and methods of making pesticidal minicells.

公开(公告)号：US11987800B2

公开(公告)日：2024-05-21

申请号：US17934287

申请日：2022-09-22

申请人： Monsanto Technology LLC

发明人： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe

IPC分类号： C12N15/82 ,  A01N63/50 ,  C07K14/24 ,  C07K14/325

CPC分类号： C12N15/8286 ,  A01N63/50 ,  C07K14/24 ,  C07K14/325

摘要： A pesticidal protein class of PirA, PirB, and PirAB fusion proteins exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the PirA, PirB, and PirAB fusion proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran, Lepidopteran, and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the PirA, PirB, and PirAB fusion proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the PirA, PirB, and PirAB fusion proteins are also provided.

公开(公告)号：US20240117374A1

公开(公告)日：2024-04-11

申请号：US18497825

申请日：2023-10-30

申请人： Monsanto Technology LLC

发明人： Timothy K. Ball ,  Artem G. Evdokimov ,  Larry A. Gilbertson ,  Victor M. Guzov ,  Jeffrey A. Haas ,  Qing Huai ,  Sergey Ivashuta ,  Melissa M. Kemp ,  Yifei Kong ,  Thomas M. Malvar ,  Byron V. Olsen ,  Parthasarathy Ramaseshadri ,  Brian E. Weiner

IPC分类号： C12N15/82 ,  A01N37/44 ,  A01N37/46 ,  C07K14/325

CPC分类号： C12N15/8286 ,  A01N37/44 ,  A01N37/46 ,  C07K14/325 ,  Y02A40/146

摘要： Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.

公开(公告)号：US20240052364A1

公开(公告)日：2024-02-15

申请号：US18479472

申请日：2023-10-02

申请人： AGBIOME, INC.

发明人： JESSICA PARKS ,  KIRA BULAZEL ROBERTS ,  REBECCA E. THAYER

IPC分类号： C12N15/82 ,  C07K14/325 ,  C07K14/00

CPC分类号： C12N15/8286 ,  C07K14/325 ,  C07K14/001

摘要： Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptide sequences having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the pesticidal polypeptides, DNA constructs comprising the nucleic acid molecules, vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the pesticidal polypeptides. Nucleotide sequences encoding the polypeptides provided herein can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest, including microorganisms and plants. The compositions and methods provided herein are useful for production of organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests. Methods are provided for producing the various polypeptides disclosed herein, and for using those polypeptides for controlling or killing a pest.

公开(公告)号：US11845949B2

公开(公告)日：2023-12-19

申请号：US17459303

申请日：2021-08-27

申请人： Monsanto Technology LLC

发明人： Heather M. Anderson ,  Sarah L. Brown ,  Renato A. Carvalho ,  Ancideriton A. Castro ,  Katherine M. Dunkmann ,  Adam J. Evans ,  Stanislaw Flasinski ,  Cara L. Griffith ,  Tianxiang Shen ,  Todd R. Smith ,  Heidi M. Windler

IPC分类号： C12N15/82 ,  C07K14/325 ,  C12Q1/6895 ,  C12N15/10

CPC分类号： C12N15/8286 ,  C07K14/325 ,  C12N15/102 ,  C12N15/8274 ,  C12Q1/6895 ,  C12Q2600/13 ,  Y02A40/146

摘要： The invention provides a transgenic corn event MON 95379, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379. The invention also provides polynucleotides specific for event MON 95379 and methods for using and detecting event MON 95379 as well as plants, plant cells, seeds, plant pails, progeny plants, and commodity products comprising event MON 95379.

公开(公告)号：US11825850B2

公开(公告)日：2023-11-28

申请号：US17556428

申请日：2021-12-20

申请人： Monsanto Technology LLC

发明人： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Matthew S. Marengo ,  Jason Meyer ,  Jason S Milligan ,  Brian E. Weiner

IPC分类号： A01N63/50 ,  C07K14/32 ,  C12N15/82 ,  C12Q1/68 ,  C07K14/325 ,  C12Q1/6895

CPC分类号： A01N63/50 ,  C07K14/325 ,  C12N15/8286 ,  C12Q1/6895

摘要： Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4029, TIC4029_1, and TIC4029_8. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding pesticidal proteins of the TIC4029 class. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the TIC4029 class in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4029, TIC4029_1, and TIC4029_8 pesticidal proteins are also provided.

公开(公告)号：US20230348543A1

公开(公告)日：2023-11-02

申请号：US18319022

申请日：2023-05-17

申请人： Monsanto Technology LLC

发明人： James A. BAUM ,  David J. BOWEN ,  Catherine A. CHAY ,  David J. CHI ,  William P. CLINTON ,  Crystal L. DART ,  Leigh ENGLISH ,  Stanislaw FLASINSKI ,  Victor M. GUZOV ,  Kevin A. JARRELL ,  Uma R. KESANAPALLI ,  Thomas M. MALVAR ,  Robert M. MCCARROLL ,  Jason S. MILLIGAN ,  Jay P. MORGENSTERN ,  Deborah G. RUCKER ,  Sara A. SALVADOR ,  Temple F. SMITH ,  Carlos E. SOTO ,  Collin M. STULTZ ,  Brian M. TURCZYK ,  Ty T. VAUGHN ,  Moritz W.F. VON RECHENBERG

IPC分类号： C07K14/325 ,  A01N63/50 ,  C12N15/82

CPC分类号： C07K14/325 ,  A01N63/50 ,  C12N15/8286 ,  Y02A40/146

摘要： Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.

公开(公告)号：US11795471B2

公开(公告)日：2023-10-24

申请号：US17936908

申请日：2022-09-30

申请人： AGRIGENETICS, INC.

发明人： Sek Yee Tan ,  Joel J Sheets ,  Todd P Glancy ,  Aaron Todd Woosley ,  Sarah E Worden ,  Diaa Alabed ,  Stephanie Love Burton ,  Karen C Mclaughlin ,  Kenneth Narva ,  Thomas Meade

IPC分类号： C12N15/82 ,  A01N63/23 ,  A01N63/50 ,  C07K14/325

CPC分类号： C12N15/8286 ,  A01N63/23 ,  A01N63/50 ,  C07K14/325 ,  Y02A40/146 ,  A01N63/50 ,  A01N63/23

摘要： The subject invention relates in part to the surprising discovery that Cry1Da is active against corn earworm (CEW), Helicoverpa zea (Boddie). Methods for using Cry1Da in transgenic plants to prevent serious crop damage is described. Leaf and silk bioassays using transgenic maize expressing full length, core toxin region or chimeric Cry1Da demonstrated good insect protection against CEW larvae damage.