公开(公告)号：US20160209363A1

公开(公告)日：2016-07-21

申请号：US15023575

申请日：2014-09-23

Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION

Inventor： David E. CLEMMER ,  Michael A. Ewing

IPC: G01N27/62

CPC classification number: G01N27/622

Abstract: A hybrid ion mobility spectrometer includes a single-pass drift tube having an ion inlet at one end and an ion outlet at an opposite end, a multiple-pass drift tube having an ion inlet and an ion outlet each coupled to the single pass drift tube between the ion inlet and the ion outlet thereof, and a set of ion gates each controllable between an open position to pass ions therethrough and a closed position to block ions from passing therethrough. The set of ion gates may be controlled to pass at least some ions traveling through the single-pass drift tube into the multiple-pass drift tube via the ion inlet of the multiple-pass drift tube and to pass at least some ions traveling through the multiple-pass drift tube into the single-pass drift tube via the ion outlet of the multiple-pass drift tube.

Abstract translation: 混合离子迁移谱仪包括一端具有离子入口和相对端的离子出口的单通漂移管，具有离子入口和离子出口的多通漂移管，每个离子入口和离子出口各自耦合到单程漂移管 在离子入口和离子出口之间，以及一组离子门，每个离子门都可以在通过离子的打开位置和闭合位置之间控制，以阻止离子通过。 可以控制该组离子浇口使至少一些通过单通漂移管传播的离子通过多通漂移管的离子入口传递到多通漂移管中，并使至少一些离子通过 多通漂移管通过多通漂移管的离子出口进入单程漂移管。

公开(公告)号：US20210078004A1

公开(公告)日：2021-03-18

申请号：US16772394

申请日：2018-12-05

Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION

Inventor： David E. CLEMMER ,  Tarik J. EL-BABA ,  Daniel R. FULLER ,  Daniel W. WOODALL ,  David H. RUSSELL ,  Evan R. WILLIAMS

IPC: B01L3/00 ,  G01N33/68

Abstract: An instrument for energizing molecules contained in a sample solution may include a droplet generator configured to generate droplets of the sample solution. The droplet generator illustratively has an elongated nozzle defining an orifice at one end thereof from which the droplets exit the droplet generator, and the orifice illustratively defines a first longitudinal axis centrally therethrough. A molecule energizing source is configured to produce a molecule energizing field, and is positioned relative to the nozzle orifice such that the molecule energizing field extends into at least some of the generated droplets along a direction non-parallel with the first longitudinal axis. The molecule energizing field illustratively carries energy which heats at least one of the generated droplets sufficiently to induce structural changes in at least one molecule contained in the at least one of the generated droplets.