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公开(公告)号:US12112935B2
公开(公告)日:2024-10-08
申请号:US17613796
申请日:2020-05-29
申请人: Micromass UK Limited
发明人: Kevin Giles , Jakub Ujma , James Harrison , Bharat Chande , Graham Scambler
IPC分类号: H01J49/06 , G01N27/622 , H01J49/02
CPC分类号: H01J49/065 , G01N27/622 , H01J49/022 , H01J49/025
摘要: An ion guide or ion trap that comprises a plurality of electrodes (102) is disclosed. The ion guide or ion trap includes a detector (205) that can detect light or particles (114) emitted from the ion guide or ion trap due to electrical breakdown, and a control circuit (111) that can control the ion guide or ion trap in response to the detector (205) detecting light or particles (114) emitted from the ion guide or ion trap.
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公开(公告)号:US20240186132A1
公开(公告)日:2024-06-06
申请号:US18546931
申请日:2022-02-18
申请人: Philip MARRIOTT
发明人: Philip MARRIOTT
IPC分类号: H01J49/06 , G01N27/622 , H01J49/04
CPC分类号: H01J49/061 , G01N27/622 , H01J49/0422
摘要: A multipole ion optical device comprises a first plurality of electrodes distributed along a first axis; and a second plurality of electrodes distributed along a second axis, generally parallel to the first axis, to define an ion channel between the first and second pluralities of electrodes. Each of the first plurality of electrodes and the second plurality of electrodes is configured to receive a respective RF voltage having an asymmetric waveform and such that adjacent electrodes of the first and second pluralities of electrodes receive RF voltages having different phases. The first and second plurality of electrodes and the plurality of RF voltages are configured such that a strength of an electric field in the ion channel is sufficient for ions to experience mobility variation.
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公开(公告)号:US20240125736A1
公开(公告)日:2024-04-18
申请号:US18090950
申请日:2022-12-29
IPC分类号: G01N27/622 , G01N33/18 , H01L21/02
CPC分类号: G01N27/622 , G01N33/1813 , H01L21/02186 , H01L21/02381
摘要: The present invention relates to a Cu ion sensor, which greatly improves the sensitivity to Cu by a nitrogen-rich surface of a copper nitride thin film doped with a metal material. The present invention also relates to a Cu ion sensing method, in which Cu2+ is detected by contacting the Cu ion sensor of the present invention with the solution to be tested, and using the change in electrical conductivity of a copper nitride film doped with a metal material in the presence of Cu2+ in the solution.
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公开(公告)号:US11837455B2
公开(公告)日:2023-12-05
申请号:US17831951
申请日:2022-06-03
发明人: Robert Graham Cooks , Zane Baird , Pu Wei
IPC分类号: H01J49/00 , H01J49/24 , H01J49/06 , G01N27/623 , G01N27/622 , H01J49/14
CPC分类号: H01J49/24 , G01N27/622 , G01N27/623 , H01J49/0013 , H01J49/061 , H01J49/142
摘要: The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.
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公开(公告)号:US11788987B2
公开(公告)日:2023-10-17
申请号:US17412997
申请日:2021-08-26
发明人: Qunzhou Bian , John J. Carroll
CPC分类号: G01N27/622 , B08B6/00 , G01N23/00 , H01J49/0031 , H01J49/025 , H01J49/04 , H01J49/06 , H01J49/061 , G06F2218/10
摘要: Method and systems for managing clear-down are provided. The method can include generating a clear-down trigger associated with an ion mobility spectrometer and operating the ion mobility spectrometer in fast clear-down mode in response to the clear-down trigger. Methods and systems can further provide that where the ion mobility spectrometer operates in fast-switching mode, the ion mobility spectrometer alternating a plurality of times between operation according to a positive ion mode and operation according to a negative ion mode, and further operating according to the positive ion mode for less than about 1 second before switching to the operation according to the negative ion mode, and operating according to the negative ion mode for less than about 1 second before switching to the operation according to the positive ion mode.
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公开(公告)号:US11662333B2
公开(公告)日:2023-05-30
申请号:US17223852
申请日:2021-04-06
IPC分类号: G01N27/622 , H01J49/42
CPC分类号: G01N27/622 , H01J49/4215
摘要: A system for filtering ions includes first and second surfaces extending along first and second perpendicularly arranged directions, an ion channel between the surfaces configured to receive an ion stream, and first and second electrode arrays associated with the first and second surfaces, respectively. The first and second electrode arrays include a first plurality of electrodes arranged along the first direction and a second plurality of electrodes arranged along the second direction. A controller is configured to apply a first voltage signal to the first plurality of electrodes, which are configured to generate a drive potential traveling along the first direction, and a second voltage signal to the electrode arrays, which are configured to generate an electric potential. The drive and electric potentials are configured to direct ions having mobilities in a first range along a first path and ions having mobilities in a second range along a second path.
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公开(公告)号:US20190237314A1
公开(公告)日:2019-08-01
申请号:US15753621
申请日:2016-08-19
CPC分类号: H01J49/0009 , G01N27/622 , G01R19/0061 , H01J49/027 , H01J49/10 , H01J49/165 , H01J49/168 , H01J49/30
摘要: The present invention comprises novel methods of continuously monitoring the performance of an atmospheric pressure ionization (API) system. The methods of the invention allow for improved quality monitoring of the processes that leads to the formation of ions at atmospheric pressure. The methods of the invention further allow for continuously monitoring for the quality of the ion formation process in API without the addition of extraneous material (such as labelled compounds or control known compounds) to the system being monitored.
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公开(公告)号:US20190234905A1
公开(公告)日:2019-08-01
申请号:US16376986
申请日:2019-04-05
发明人: Qingjun Zhang , Yuanjing Li , Zhiqiang Chen , Ziran Zhao , Yinong Liu , Yaohong Liu , Huishao He , Qiufeng Ma , Weiping Zhu , Xiang Zou , Jianping Chang , Song Liang
CPC分类号: G01N27/622 , G01N1/02 , G01N1/2211 , G01N1/405 , G01N1/42 , G01N30/60 , G01N30/722 , G01N2001/028 , H01J49/0422 , H01J49/0459 , H01J49/0468 , G01N30/6043 , G01N30/6078
摘要: A detection apparatus and a detection method are disclosed. In one aspect, the detection apparatus includes a sampling device for collecting samples to be checked. It further includes a sample pre-processing device configured to pre-process the sample from the sampling device. It further includes a sample analyzing device for separating samples from the pre-processing device and for analyzing the separated samples. The detection apparatus is miniaturized and highly precise, and is capable of quickly and accurately detecting gaseous phase or particulate substances, and it has applications for safety inspections at airports, ports, and subway stations.
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9.
公开(公告)号:US20190212297A1
公开(公告)日:2019-07-11
申请号:US16335128
申请日:2017-09-19
申请人: MICROMASS UK LIMITED
CPC分类号: G01N27/622 , H01J49/40
摘要: A method of ion mobility spectrometry is disclosed comprising: transmitting a plurality of ions to an ion mobility separator 6; modulating the introduction of the ions into the ion mobility separator 6 at a first modulation frequency; separating the ions that enter the ion mobility separator 6 according to ion mobility; detecting ions that have exited the ion mobility separator with a detector of a time of flight mass analyser 8; varying the first modulation frequency with time; recording the intensity of the ion signal output from the detector to produce recorded data; modulating the recorded data as a function of the time that the data was recorded and at a second modulation frequency, wherein the second modulation frequency is varied as a function of the time that the data was recorded; and determining, from the variation in intensity of the ion signal in the modulated data as a function of the second modulation frequency, the ion mobilities of the ions that have been detected.
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公开(公告)号:US20180340910A1
公开(公告)日:2018-11-29
申请号:US15603600
申请日:2017-05-24
申请人: Bruker Daltonik GmbH
发明人: Thomas BETZ , Melvin Andrew PARK , Mark RIDGEWAY
IPC分类号: G01N27/62
CPC分类号: G01N27/622 , H01J49/0031 , H01J49/004
摘要: The invention proposes a mass spectrometer comprising two ion mobility analyzers in tandem arrangement, of which at least one is a trapped ion mobility spectrometer (TIMS), and an ion gate which is located between the two ion mobility analyzers, and use thereof wherein ions are selectively transferred between the two ion mobility analyzers by adjusting the transmission of the ion gate while ions are separated in time according to ion mobility in the first ion mobility analyzer.
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