HIGH PRESSURE ION OPTICAL DEVICES
    2.
    发明公开

    公开(公告)号:US20240186132A1

    公开(公告)日:2024-06-06

    申请号:US18546931

    申请日:2022-02-18

    申请人: Philip MARRIOTT

    发明人: Philip MARRIOTT

    摘要: A multipole ion optical device comprises a first plurality of electrodes distributed along a first axis; and a second plurality of electrodes distributed along a second axis, generally parallel to the first axis, to define an ion channel between the first and second pluralities of electrodes. Each of the first plurality of electrodes and the second plurality of electrodes is configured to receive a respective RF voltage having an asymmetric waveform and such that adjacent electrodes of the first and second pluralities of electrodes receive RF voltages having different phases. The first and second plurality of electrodes and the plurality of RF voltages are configured such that a strength of an electric field in the ion channel is sufficient for ions to experience mobility variation.

    Systems and methods for two-dimensional mobility based filtering of ions

    公开(公告)号:US11662333B2

    公开(公告)日:2023-05-30

    申请号:US17223852

    申请日:2021-04-06

    IPC分类号: G01N27/622 H01J49/42

    CPC分类号: G01N27/622 H01J49/4215

    摘要: A system for filtering ions includes first and second surfaces extending along first and second perpendicularly arranged directions, an ion channel between the surfaces configured to receive an ion stream, and first and second electrode arrays associated with the first and second surfaces, respectively. The first and second electrode arrays include a first plurality of electrodes arranged along the first direction and a second plurality of electrodes arranged along the second direction. A controller is configured to apply a first voltage signal to the first plurality of electrodes, which are configured to generate a drive potential traveling along the first direction, and a second voltage signal to the electrode arrays, which are configured to generate an electric potential. The drive and electric potentials are configured to direct ions having mobilities in a first range along a first path and ions having mobilities in a second range along a second path.

    ION MOBILITY MASS SPECTROMETER AND METHOD OF PERFORMING ION MOBILITY MASS SPECTROMETRY

    公开(公告)号:US20190212297A1

    公开(公告)日:2019-07-11

    申请号:US16335128

    申请日:2017-09-19

    IPC分类号: G01N27/62 H01J49/40

    CPC分类号: G01N27/622 H01J49/40

    摘要: A method of ion mobility spectrometry is disclosed comprising: transmitting a plurality of ions to an ion mobility separator 6; modulating the introduction of the ions into the ion mobility separator 6 at a first modulation frequency; separating the ions that enter the ion mobility separator 6 according to ion mobility; detecting ions that have exited the ion mobility separator with a detector of a time of flight mass analyser 8; varying the first modulation frequency with time; recording the intensity of the ion signal output from the detector to produce recorded data; modulating the recorded data as a function of the time that the data was recorded and at a second modulation frequency, wherein the second modulation frequency is varied as a function of the time that the data was recorded; and determining, from the variation in intensity of the ion signal in the modulated data as a function of the second modulation frequency, the ion mobilities of the ions that have been detected.

    MASS SPECTROMETER WITH TANDEM ION MOBILITY ANALYZERS

    公开(公告)号:US20180340910A1

    公开(公告)日:2018-11-29

    申请号:US15603600

    申请日:2017-05-24

    IPC分类号: G01N27/62

    摘要: The invention proposes a mass spectrometer comprising two ion mobility analyzers in tandem arrangement, of which at least one is a trapped ion mobility spectrometer (TIMS), and an ion gate which is located between the two ion mobility analyzers, and use thereof wherein ions are selectively transferred between the two ion mobility analyzers by adjusting the transmission of the ion gate while ions are separated in time according to ion mobility in the first ion mobility analyzer.