公开(公告)号：US20230190677A1

公开(公告)日：2023-06-22

申请号：US17858233

申请日：2022-07-06

Applicant: INDUSTRY ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

Inventor： Gwang Won CHO ,  Nagarajan MAHARAJAN

IPC: A61K31/12 ,  A61P39/06 ,  A23L33/105 ,  A61K8/35 ,  A61Q19/08

CPC classification number: A61K31/12 ,  A61P39/06 ,  A23L33/105 ,  A61K8/35 ,  A61Q19/08 ,  A61K2800/522

Abstract: A method for treatment of aging-related disease includes administering a composition including a compound represented by Formula 1 or a pharmaceutically, sitologically or cosmetically acceptable salt thereof to a subject in need thereof. The composition has excellent AMP-activated protein kinase (AMPK) and autophagy activation effects, thereby being helpful to prevent aging.

公开(公告)号：US20230190682A1

公开(公告)日：2023-06-22

申请号：US17967273

申请日：2022-10-17

Applicant: Industry Academic Cooperation Foundation Chosun University

Inventor： Gwang Won CHO ,  Nagarajan MAHARAJAN

IPC: A61K31/125 ,  A61P3/10 ,  A61P3/04 ,  A61P1/16 ,  A61P3/06 ,  A23L33/10 ,  A23L33/00

CPC classification number: A61K31/125 ,  A23L33/10 ,  A23L33/40 ,  A61P1/16 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10

Abstract: A method for preventing or treating metabolic diseases includes administering a composition including a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof to a subject in need thereof. Thereby, it is possible to inhibit increases in body weight and liver fat weight due to a high-calorie diet, and decrease an accumulation of fat in the liver tissue, as well as modulate gene expression related to fat metabolism, and ultimately exhibit excellent preventive and therapeutic effects on metabolic diseases.