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公开(公告)号：US10577416B2
公开(公告)日：2020-03-03
申请号：US14377274
申请日：2013-02-07
Applicant: INNATE PHARMA, S.A.
Inventor： Mathieu Blery , Laurent Gauthier , Ivan Perrot , Cecile Bonnafous
IPC: C07K16/28 , A61K39/00 , G01N33/569
Abstract: The present invention relates to methods for the treatment of disorders mediated by MICA-expressing cells using antibodies, antibody fragments, and derivatives thereof that specifically bind MICA. The invention also relates to antibodies; cells producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; and pharmaceutical compositions comprising the same.
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Patent Agency Ranking
公开(公告)号：US10736963B2
公开(公告)日：2020-08-11
申请号：US15747190
申请日：2016-07-04
Applicant: INNATE PHARMA
Inventor： Nadia Anceriz , Cecile Bonnafous , Arnaud Dujardin , Carine Paturel
IPC: A61K39/00 , A61K39/395 , G01N33/566 , G01N33/574 , C07K16/28 , A61P35/00
Abstract: The present invention relates to methods for detecting and monitoring NK cells in paraffin-embedded tissue samples. Also provided are antibodies, antibody fragments, and derivatives thereof that specifically bind to NKp46 present on the surface of NK cells in paraffin-embedded tissue samples.
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3.发明授权公开(公告)号：US11078275B2
公开(公告)日：2021-08-03
申请号：US16240906
申请日：2019-01-07
Applicant: INNATE PHARMA
Inventor： Cecile Bonnafous , Helene Sicard , Renaud Buffet
IPC: C07K16/28 , C07K16/30 , G01N33/574 , A61K39/00
Abstract: The present invention relates to methods for the treatment, prevention and diagnosis of peripheral T cell lymphoma using compounds that specifically bind KIR3DL2. The invention also relates to use of antibodies that specifically bind KIR3DL2 in diagnostic and theranostic assays in the detection and treatment of peripheral T cell lymphoma.
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公开(公告)号：US20150191542A1
公开(公告)日：2015-07-09
申请号：US14377274
申请日：2013-02-07
Applicant: INNATE PHARMA, S.A.
Inventor： Mathieu Blery , Laurent Gauthier , Ivan Perrot , Cecile Bonnafous
IPC: C07K16/28 , G01N33/569
CPC classification number: C07K16/28 , A61K2039/505 , C07K16/2833 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/56977 , G01N2333/70539
Abstract: The present invention relates to methods for the treatment of disorders mediated by MICA-expressing cells using antibodies, antibody fragments, and derivatives thereof that specifically bind MICA. The invention also relates to antibodies; cells producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; and pharmaceutical compositions comprising the same.
Abstract translation: 本发明涉及使用特异性结合MICA的抗体，抗体片段及其衍生物治疗由MICA表达细胞介导的病症的方法。 本发明还涉及抗体; 产生这种抗体的细胞; 制备此类抗体的方法; 抗体的片段，变体和衍生物; 和包含其的药物组合物。
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公开(公告)号：US20200299380A1
公开(公告)日：2020-09-24
申请号：US16804705
申请日：2020-02-28
Applicant: Innate Pharma
Inventor： Mathieu Blery , Laurent Gauthier , Ivan Perrot , Cecile Bonnafous
IPC: C07K16/28 , G01N33/569
Abstract: The present invention relates to methods for the treatment of disorders mediated by MICA-expressing cells using antibodies, antibody fragments, and derivatives thereof that specifically bind MICA. The invention also relates to antibodies; cells producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; and pharmaceutical compositions comprising the same.
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6.发明授权公开(公告)号：US10174112B2
公开(公告)日：2019-01-08
申请号：US15623572
申请日：2017-06-15
Applicant: INNATE PHARMA
Inventor： Cecile Bonnafous , Helene Sicard , Renaud Buffet
IPC: A61K39/00 , A61K39/395 , C07K16/28 , C07K16/30 , G01N33/574
Abstract: The present invention relates to methods for the treatment, prevention and diagnosis of peripheral T cell lymphoma using compounds that specifically bind KIR3DL2. The invention also relates to use of antibodies that specifically bind KIR3DL2 in diagnostic and theranostic assays in the detection and treatment of peripheral T cell lymphoma.
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