公开(公告)号：US11243166B2

公开(公告)日：2022-02-08

申请号：US16545023

申请日：2019-08-20

Applicant: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCES

Inventor： Jie Tian ,  Zhenhua Hu ,  Caiguang Cao ,  Zeyu Zhang ,  Meishan Cai

IPC: G01N21/47 ,  A61B6/00 ,  G01N21/64 ,  H04N5/33

Abstract: An intraoperative near-infrared-I and near-infrared-II multi-spectral fluorescent navigation system and method of using same includes a light source module for emitting white light and excitation light for illuminating tissue to be tested to generate an emission light. An optical information collection module includes a white light camera for collecting the white light image, and near infrared-I and near infrared-II fluorescence cameras for collecting the near infrared-I and near infrared-II fluorescence images. A central control module is coupled to the light source and the optical information collection modules. An image processing unit pre-processes the white light image, and the near infrared-I and near infrared-II fluorescence images, for de-noising and enhancement. The image processing unit performs a pseudo-color mapping on the images to obtain pseudo-color superimposed images of the near infrared-I and near infrared-II for a surgical region, and completes imaging of the intraoperative near-infrared-I and near-infrared-II multi-spectral fluorescent navigation system.

公开(公告)号：US12004886B2

公开(公告)日：2024-06-11

申请号：US16845267

申请日：2020-04-10

Applicant: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCES

Inventor： Jie Tian ,  Zhenhua Hu ,  Meishan Cai ,  Caiguang Cao

IPC: A61B6/03 ,  A61B5/00 ,  A61B6/00 ,  A61B6/50 ,  G06T7/00 ,  G06T11/00 ,  G06V10/141

CPC classification number: A61B6/032 ,  A61B5/0035 ,  A61B5/0071 ,  A61B5/0073 ,  A61B6/508 ,  A61B6/5247 ,  A61B6/54 ,  A61B6/56 ,  G06T7/0012 ,  G06T11/001 ,  G06V10/141 ,  A61B2503/40 ,  A61B2562/0233 ,  G06T2207/10064 ,  G06T2207/10081 ,  G06T2207/10116 ,  G06T2207/30004

Abstract: A second near-infrared window/first near-infrared window dual-mode fluorescence tomography system having a lighting module, an excitation module, a second near-infrared window collection module, a first near-infrared window collection module, a CT imaging module and a central control module. The central control module is configured to reconstruct second near-infrared window three-dimensional and tomographic images and first near-infrared window three-dimensional and tomographic images based on the white light images, the second near-infrared window fluorescent images, the first near-infrared window fluorescent images, and the CT images. The reconstructed three-dimensional space tumor signal has depth characteristics, which is closer to the real distribution of tumors, such that the reconstruction position is more accurate. The three-dimensional shape of the tumor is displayed intuitively and clearly at any angle with the usage of image display unit.