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公开(公告)号：US11835602B1
公开(公告)日：2023-12-05
申请号：US18144256
申请日：2023-05-08
Inventor： Yang Du , Jie Tian , Zhengyao Peng , Lin Yin , Qian Liang
CPC classification number: G01R33/1276 , G06N3/091 , G06T11/003
Abstract: An MPI reconstruction method, device, and system based on a RecNet model include obtaining a one-dimensional (1D) MPI signal on which imaging reconstruction is to be performed, taking the 1D MPI signal as an input signal, and inputting the input signal and a velocity signal of an FFP corresponding to the input signal into a trained magnetic particle reconstruction model RecNet for image reconstruction to obtain a two-dimensional (2D) MPI image, where the magnetic particle reconstruction model RecNet is constructed based on a domain conversion network and an improved UNet network. The MPI reconstruction method, device, and system obtain a high-quality and clear magnetic particle distribution image without obtaining the system matrix.
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公开(公告)号：US11243166B2
公开(公告)日：2022-02-08
申请号：US16545023
申请日：2019-08-20
Inventor： Jie Tian , Zhenhua Hu , Caiguang Cao , Zeyu Zhang , Meishan Cai
Abstract: An intraoperative near-infrared-I and near-infrared-II multi-spectral fluorescent navigation system and method of using same includes a light source module for emitting white light and excitation light for illuminating tissue to be tested to generate an emission light. An optical information collection module includes a white light camera for collecting the white light image, and near infrared-I and near infrared-II fluorescence cameras for collecting the near infrared-I and near infrared-II fluorescence images. A central control module is coupled to the light source and the optical information collection modules. An image processing unit pre-processes the white light image, and the near infrared-I and near infrared-II fluorescence images, for de-noising and enhancement. The image processing unit performs a pseudo-color mapping on the images to obtain pseudo-color superimposed images of the near infrared-I and near infrared-II for a surgical region, and completes imaging of the intraoperative near-infrared-I and near-infrared-II multi-spectral fluorescent navigation system.
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公开(公告)号：US12136146B1
公开(公告)日：2024-11-05
申请号：US18752758
申请日：2024-06-24
Inventor： Jie Tian , Zechen Wei , Hui Hui , Xin Yang
IPC: G06T11/00 , A61B5/0515 , G06T3/4046
Abstract: A system for reconstructing a magnetic particle image based on a pre-trained model aims to address the influence by point spread function and reduce the computational and time costs, which results in low reconstruction accuracy, or high acquisition time and computational costs for high-precision images. The system is implemented by: generating a simulation system matrix; pre-training a pre-constructed neural network model, and fine-tuning a pre-trained neural network model by performing a downstream task; and inputting real data corresponding to the downstream task into the pre-trained neural network model after fine-tuning, thereby playing an auxiliary role to acquire a high-quality reconstructed MPI image. The system fits the relationship between different harmonics, which helps enhance frequency-domain information. The system has certain universality and can be generalized to a plurality of downstream tasks related to MPI image reconstruction, thereby acquiring high-quality reconstructed images through simple model fine-tuning.
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公开(公告)号：US12004886B2
公开(公告)日：2024-06-11
申请号：US16845267
申请日：2020-04-10
Inventor： Jie Tian , Zhenhua Hu , Meishan Cai , Caiguang Cao
CPC classification number: A61B6/032 , A61B5/0035 , A61B5/0071 , A61B5/0073 , A61B6/508 , A61B6/5247 , A61B6/54 , A61B6/56 , G06T7/0012 , G06T11/001 , G06V10/141 , A61B2503/40 , A61B2562/0233 , G06T2207/10064 , G06T2207/10081 , G06T2207/10116 , G06T2207/30004
Abstract: A second near-infrared window/first near-infrared window dual-mode fluorescence tomography system having a lighting module, an excitation module, a second near-infrared window collection module, a first near-infrared window collection module, a CT imaging module and a central control module. The central control module is configured to reconstruct second near-infrared window three-dimensional and tomographic images and first near-infrared window three-dimensional and tomographic images based on the white light images, the second near-infrared window fluorescent images, the first near-infrared window fluorescent images, and the CT images. The reconstructed three-dimensional space tumor signal has depth characteristics, which is closer to the real distribution of tumors, such that the reconstruction position is more accurate. The three-dimensional shape of the tumor is displayed intuitively and clearly at any angle with the usage of image display unit.
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公开(公告)号：US12117508B1
公开(公告)日：2024-10-15
申请号：US18744685
申请日：2024-06-16
Inventor： Jie Tian , Zechen Wei , Hui Hui , Liwen Zhang , Xin Yang , Tao Zhu
IPC: G01R33/12 , A61B5/0515 , G06T11/00
CPC classification number: G01R33/1276 , A61B5/0515 , G06T11/006 , G06T2211/441
Abstract: A system for reconstructing a magnetic particle image based on adaptive optimization of regularization terms includes: a MPI device for scanning an imaging object to acquire a voltage response signal; a signal processor for constructing a system matrix; and a control processor for reconstructing the magnetic particle image based on an arbitrarily selected regularization term, inputting the reconstructed magnetic particle image to a regularization-term adaptive optimization neural network model for enhancement processing, taking the enhanced magnetic particle image as a first image, and calculating a loss value between the first image and an initial image to acquire a final reconstructed magnetic particle image. The system adopts a neural network model-based automatic learning approach, instead of the approach of manually selecting regularization terms and adjusting parameters, to improve the reconstruction efficiency and quality of the magnetic particle image.
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Patent Agency Ranking
6.发明授权公开(公告)号：US10939845B2
公开(公告)日：2021-03-09
申请号：US16907334
申请日：2020-06-22
Inventor： Jie Tian , Peng Zhang , Hui Hui , Kun Wang , Xin Yang
IPC: A61B5/0515 , A61B5/00
Abstract: A FFL-based magnetic particle imaging three-dimensional reconstruction method includes: acquiring current signal data of an induction coil during FFL-based three-dimensional scanning process of a scanned object; based on the current signal data, performing deconvolution through a preset kernel function to acquire a two-dimensional image data set, wherein the kernel function is a step function with L2 regularized constraint; based on the two-dimensional image data set, acquiring an initial three-dimensional image by using a Wiener filtering deconvolution algorithm; and based on the initial three-dimensional image, performing deconvolution through a Langevin function, and acquiring a final three-dimensional image by Radon transformation. A FFL-based magnetic particle imaging three-dimensional reconstruction system includes a magnet group, an induction coil, an imaging bed, and a control and imaging device, wherein, a magnetic particle imaging method in the control and imaging device is the FFL-based magnetic particle imaging three-dimensional reconstruction method.
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公开(公告)号：US10026202B2
公开(公告)日：2018-07-17
申请号：US15289535
申请日：2016-10-10
Inventor： Jie Tian , Kunshan He , Chongwei Chi , Xin Yang
CPC classification number: G06T11/003 , A61B5/0075 , A61B5/6803 , G01B11/00 , G01B11/24 , H04N5/2256 , H04N5/2258 , H04N5/332
Abstract: The invention discloses a wearable molecular imaging navigation system comprising: a multi-spectral light transceiver configured to transmit a multi-spectral light to a detected subject in a detection region and acquire an emitting light regarding the detected subject and acquire a reflecting light regarding the detected subject; an image processor configured to receive the reflecting light and the emitting light from the multi-spectral light transceiver, execute a three-dimensional reconstruction and fusion process on the reflecting light and the emitting light to obtain a fusion image; a wireless signal processor configured to enable a wireless communication; and a wearable device, configured to receive the fusion image from the image processor via the wireless signal processor, display the fusion image and control the multi-spectral light transceiver and the image processor based on instructions received.
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公开(公告)号：US20180042481A1
公开(公告)日：2018-02-15
申请号：US15520928
申请日：2014-10-22
Inventor： Jie Tian , Chongwei Chi , Xin Yang
Abstract: A handheld molecular imaging navigation system comprises a multi-spectral light source module configured to provide light in a plurality of different spectrum bands in a time division control manner according to a control signal sequence to irradiate an inspected object; a time division control module configured to generate the control signal sequence; an optical signal acquisition module configured to acquire a near-infrared fluorescence image and a visible light image of the inspected object in a time division control manner according to the control signal sequence provided by the time division control module; and a processing module configured to perform image processing on the acquired near-infrared fluorescence image and visible light image according to the control signal sequence to fuse the visible light image and the fluorescence image and output the fused image, and output a feedback signal according to the acquired near-infrared fluorescence image and visible light image.
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9.发明授权公开(公告)号：US12136145B2
公开(公告)日：2024-11-05
申请号：US17811738
申请日：2022-07-11
IPC: G06T11/00 , A61B5/00 , A61B5/0515
Abstract: The present disclosure includes: transforming a time-domain voltage signal collected by an MPI system device to a frequency domain; calculating a square root of a square sum of a real part and an imaginary part at each frequency point of a frequency domain signal; arranging acquired amplitudes in a descending order, and acquiring a screening threshold by an amplitude ratio method; screening an amplitude through the screening threshold and constructing frequency domain signal data; acquiring a row vector of a system matrix corresponding to each frequency point of the data, so as to construct an update system matrix; and solving, based on the frequency domain signal array and the update system matrix, an inverse problem in a form of a least square based on an L2 constraint to obtain a three-dimensional magnetic particle concentration distribution result, so as to achieve a fast reconstruction of the MPI system.
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10.发明授权公开(公告)号：US11771336B2
公开(公告)日：2023-10-03
申请号：US17811235
申请日：2022-07-07
Inventor： Jie Tian , Yanjun Liu , Hui Hui , Lin Yin , Xin Feng
IPC: A61B5/0515 , G01R33/54
CPC classification number: A61B5/0515 , G01R33/54
Abstract: The present disclosure belongs to a field of biomedical imaging technology, and in particularly to a non-uniform excitation field-based method and system for performing a magnetic nanoparticle imaging. The present disclosure includes: separating the non-uniform excitation field into independent space and current time functions by a spatialtemporal separation method; calculating a normalized signal peak through the current time function; constructing a reconstruction mathematical model based on the normalized signal peak and an imaging subunit volume; and quantitatively reconstructing a spatial distribution of a nanoparticle by combining the normalized signal peak, a non-uniform spatial function of the excitation field and the reconstruction mathematical model, so as to achieve the magnetic nanoparticle imaging of a to-be-reconstructed object.
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