公开(公告)号：US09689842B2

公开(公告)日：2017-06-27

申请号：US14072336

申请日：2013-11-05

Applicant: INTEL CORPORATION

Inventor： Xing Su ,  Kai Wu ,  David J Liu

IPC: G01N33/543 ,  G01N27/74 ,  B01L3/00 ,  B03C1/032 ,  B03C1/033 ,  G01R33/12 ,  B03C1/28

CPC classification number: G01N27/74 ,  B01J2219/00576 ,  B01J2219/00648 ,  B01J2219/00655 ,  B01J2219/00725 ,  B01J2219/0074 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/043 ,  B01L2400/0439 ,  B03C1/032 ,  B03C1/0335 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N27/745 ,  G01R33/1269

Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises multiple zones such as a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.