-
1.发明申请AZA-Isoindolones and Their Use as Metabotropic Glutamate Receptor Potentiators - 613 审中-公开AZA-异吲哚酮及其用作代谢型谷氨酸受体电位器 - 613公开(公告)号：US20110053953A1
公开(公告)日：2011-03-03
申请号：US12526161
申请日：2008-01-31
申请人： Abdelmalik Slassi , Methvin Isaac , Joshua Clayton , Ian Egle , Babu Joseph , Fupeng Ma
发明人： Abdelmalik Slassi , Methvin Isaac , Joshua Clayton , Ian Egle , Babu Joseph , Fupeng Ma
IPC分类号： A61K31/496 , C07D401/14 , C07D471/04 , A61K31/437 , A61P25/00
CPC分类号： C07D471/04
摘要： Compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8 and n are defined in the specification, methods for using said compounds, methods for making said compounds and pharmaceutical compositions containing said compounds.
摘要翻译： 式I化合物：其中R1，R2，R3，R4，R5，R6，R7，R8和n在本说明书中定义，使用所述化合物的方法，制备所述化合物的方法和含有所述化合物的药物组合物。
-
2.发明申请SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS 失效螺旋 - 奥沙利酮化合物及其作为代谢谷氨酸受体电位的用途公开(公告)号：US20090124578A1
公开(公告)日：2009-05-14
申请号：US12353056
申请日：2009-01-13
申请人： Ian EGLE , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
发明人： Ian EGLE , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
IPC分类号： A61K31/69 , A61K31/5377 , A61P25/28 , A61K31/423
CPC分类号： C07D263/52 , C07D413/10 , C07D413/14 , C07D417/10
摘要： Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
摘要翻译： 符合式I的化合物：其中R1，L，A，B，D，E，m，n，x和y如说明书中所定义，用于制备这些化合物的方法和用于制备其的新中间体 ，含有这些化合物的药物组合物，以及这些化合物在治疗和治疗本说明书中提及的疾病中的用途。
-
3.发明授权Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators 失效螺恶唑烷酮化合物及其作为代谢型谷氨酸受体增强剂的用途公开(公告)号：US07485722B2
公开(公告)日：2009-02-03
申请号：US11898491
申请日：2007-09-12
申请人： Ian Egle , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
发明人： Ian Egle , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
IPC分类号： C07D273/04 , C07D263/52 , C07D498/00
CPC分类号： C07D263/52 , C07D413/10 , C07D413/14 , C07D417/10
摘要： Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
摘要翻译： 符合式I的化合物：其中R1，L，A，B，D，E，m，n，x和y如说明书中所定义，用于制备这些化合物的方法和用于制备其的新中间体 ，含有这些化合物的药物组合物，以及这些化合物在治疗和治疗本说明书中提及的疾病中的用途。
-
4.发明申请Oxazolidinone Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators 审中-公开恶唑烷酮化合物及其用作代谢型谷氨酸受体电位器公开(公告)号：US20090012089A1
公开(公告)日：2009-01-08
申请号：US12095906
申请日：2006-12-06
申请人： Abdelmalik Slassi , Babu Joseph , Fupeng Ma , Ian Egle , Joshua Clayton , Methvin Isaac , Krzysztof Swierczek
发明人： Abdelmalik Slassi , Babu Joseph , Fupeng Ma , Ian Egle , Joshua Clayton , Methvin Isaac , Krzysztof Swierczek
IPC分类号： A61K31/421 , A61P25/00 , C07D263/20 , C07D401/14 , A61K31/496 , A61K31/4439 , C07D401/10 , C07D413/10 , A61K31/5377
CPC分类号： C07D413/08 , C07D263/20 , C07D413/12
摘要： The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
摘要翻译： 本发明涉及式I化合物：其中R1，R2，Y，m和n在说明书中进一步定义。 本发明还涉及制备化合物的方法和用于制备中的新中间体，含有该化合物的药物组合物，以及该化合物在治疗中的用途。
-
5.发明授权Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators 失效恶唑烷酮化合物及其作为代谢型谷氨酸受体增强剂的用途公开(公告)号：US07816354B2
公开(公告)日：2010-10-19
申请号：US11634250
申请日：2006-12-06
申请人： Abdelmalik Slassi , Methvin Isaac , Ian Egle , Fupeng Ma , Babu Joseph , Joshua Clayton , Krzysztof Swierczek
发明人： Abdelmalik Slassi , Methvin Isaac , Ian Egle , Fupeng Ma , Babu Joseph , Joshua Clayton , Krzysztof Swierczek
IPC分类号： A61K31/421 , A61K31/497 , C07D239/02 , C07D413/02
CPC分类号： C07D413/08 , C07D263/20 , C07D413/12
摘要： The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
摘要翻译： 本发明涉及式I化合物：其中R1，R2，Y，m和n在说明书中进一步定义。 本发明还涉及制备化合物的方法和用于制备中的新中间体，含有该化合物的药物组合物，以及该化合物在治疗中的用途。
-
6.发明授权Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators 失效螺恶唑烷酮化合物及其作为代谢型谷氨酸受体增强剂的用途公开(公告)号：US07790717B2
公开(公告)日：2010-09-07
申请号：US12353056
申请日：2009-01-13
申请人： Ian Egle , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
发明人： Ian Egle , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
IPC分类号： A61K31/5377 , A61K31/423
CPC分类号： C07D263/52 , C07D413/10 , C07D413/14 , C07D417/10
摘要： Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
摘要翻译： 符合式I的化合物：其中R1，L，A，B，D，E，m，n，x和y如说明书中所定义，用于制备这些化合物的方法和用于制备其的新中间体 ，含有这些化合物的药物组合物，以及这些化合物在治疗和治疗本说明书中提及的疾病中的用途。
-
7.发明申请Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators 失效螺恶唑烷酮化合物及其作为代谢型谷氨酸受体增强剂的用途公开(公告)号：US20080125431A1
公开(公告)日：2008-05-29
申请号：US11898491
申请日：2007-09-12
申请人： Ian Egle , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
发明人： Ian Egle , Babu Joseph , Abdelmalik Slassi , Methvin Isaac , Fupeng Ma , Joshua Clayton
IPC分类号： A61K31/423 , A61P25/00 , C07D263/52 , C07D413/10 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/496 , C07D413/14 , A61K31/5377
CPC分类号： C07D263/52 , C07D413/10 , C07D413/14 , C07D417/10
摘要： Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
摘要翻译： 符合式I的化合物：其中R 1，L，A，B，D，E，m，n，x和y如说明书中所定义，制备这些化合物的方法和 用于制备其中的新中间体，含有这些化合物的药物组合物，以及这些化合物在治疗和治疗本说明书中提到的疾病中的用途。
-
8.发明申请Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators 失效恶唑烷酮化合物及其作为代谢型谷氨酸受体增强剂的用途公开(公告)号：US20070275966A1
公开(公告)日：2007-11-29
申请号：US11634250
申请日：2006-12-06
申请人： Abdelmalik Slassi , Methvin Isaac , Ian Egle , Fupeng Ma , Babu Joseph , Joshua Clayton , Krzysztof Swierczek
发明人： Abdelmalik Slassi , Methvin Isaac , Ian Egle , Fupeng Ma , Babu Joseph , Joshua Clayton , Krzysztof Swierczek
IPC分类号： A61K31/421 , A61K31/497 , C07D239/02 , C07D413/02
CPC分类号： C07D413/08 , C07D263/20 , C07D413/12
摘要： The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
摘要翻译： 本发明涉及式I化合物：其中R 1，R 2，Y，m和n在说明书中进一步定义。 本发明还涉及制备化合物的方法和用于制备中的新中间体，含有该化合物的药物组合物，以及该化合物在治疗中的用途。
-
9.发明授权Substituted isoindolones and their use as metabotropic glutamate receptor potentiators 失效取代的异吲哚酮及其作为代谢型谷氨酸受体增强剂的用途公开(公告)号：US07868008B2
公开(公告)日：2011-01-11
申请号：US12063018
申请日：2006-02-15
申请人： Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
发明人： Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
IPC分类号： C07D209/46 , C07D401/06 , C07D401/14 , A61K31/4035 , A61K31/454
CPC分类号： C07D209/46 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D413/04 , C07D413/14
摘要： The present invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
摘要翻译： 本发明涉及式I化合物：其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9和n如说明书中对式I所定义。 本发明还涉及制备化合物的方法和用于制备中的新中间体，含有该化合物的药物组合物，以及该化合物在治疗中的用途。
-
公开(公告)号：US08153638B2
公开(公告)日：2012-04-10
申请号：US12861336
申请日：2010-08-23
申请人： Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James R. Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
发明人： Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James R. Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
IPC分类号： A61K31/497 , A61K31/4439 , A61K31/4035 , A61K31/427 , C07D403/14 , C07D403/02 , C07D401/02 , C07D209/44 , C07D417/02
CPC分类号： C07D209/34 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D417/04
摘要： Compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined in the description, processes for the preparing the compounds, new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and uses of the compounds in therapy.
摘要翻译： 式I化合物：其中R1，R2，R3，R4，R5，R6，R7，R8，R9和n如说明书中所定义，制备化合物的方法，制备中使用的新中间体，含有 化合物和化合物在治疗中的用途。
-
-
-
-
-
-
-
-
-
搜索结果
92 条记录 (耗时 0.034 秒)
