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公开(公告)号：US08188290B2
公开(公告)日：2012-05-29
申请号：US12091591
申请日：2006-10-26
IPC分类号： C07D211/06 , C07C69/76
CPC分类号： C07D211/74 , C07C269/04 , C07C271/04
摘要： The present invention relates to a new and useful process for preparing N,N-substituted carbamoyl halides from secondary amines, carbon dioxide, trialkylsilyl chloride and a halogenating agent.
摘要翻译： 本发明涉及从仲胺，二氧化碳，三烷基甲硅烷基氯和卤化剂制备N，N-取代的氨基甲酰卤的新的和有用的方法。
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公开(公告)号：US20080262234A1
公开(公告)日：2008-10-23
申请号：US12091591
申请日：2006-10-26
IPC分类号： C07D211/60 , C07C69/76
CPC分类号： C07D211/74 , C07C269/04 , C07C271/04
摘要： The present invention relates to a new and useful process for preparing N,N-substituted carbamoyl halides from secondary amines, carbon dioxide, trialkylsilyl chloride and a halogenating agent.
摘要翻译： 本发明涉及从仲胺，二氧化碳，三烷基甲硅烷基氯和卤化剂制备N，N-取代的氨基甲酰卤的新的和有用的方法。
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公开(公告)号：US20050080025A1
公开(公告)日：2005-04-14
申请号：US10495413
申请日：2002-11-13
申请人： Suleman Alihodzic , Daniele Andretoh , Andrea Berdik , Ilaria Bientinesi , Stefano Biondi , Manuela Ciraco , Federica Damiani , Marko Djerek , Miljenko Dumic , Vesna Erakovic , Antun Hutinec , Gorjana Lazarevski , Sergio Lociuro , Natasa Marsic , Zorica Marusic-Istuk , Stjepan Mutak , Alfred Paio , Drazen Pavlovic , Anna Quaglia , Wolfgang Schoenfeld , Vlado Stimac , Jessica Tibasco
发明人： Suleman Alihodzic , Daniele Andretoh , Andrea Berdik , Ilaria Bientinesi , Stefano Biondi , Manuela Ciraco , Federica Damiani , Marko Djerek , Miljenko Dumic , Vesna Erakovic , Antun Hutinec , Gorjana Lazarevski , Sergio Lociuro , Natasa Marsic , Zorica Marusic-Istuk , Stjepan Mutak , Alfred Paio , Drazen Pavlovic , Anna Quaglia , Wolfgang Schoenfeld , Vlado Stimac , Jessica Tibasco
IPC分类号： A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/7052
CPC分类号： C07H17/08
摘要： The present invention relates to 14 or 15 membered macrolides substituted at the 4th position of formula (I) and pharmaceutically acceptable salts and solvates thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.
摘要翻译： 本发明涉及在式（I）的第4位取代的14或15元大环内酯类及其药学上可接受的盐和溶剂化物，其制备方法及其在治疗或预防全身或局部细菌感染中的用途 一个人或动物的身体。
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公开(公告)号：US07202221B2
公开(公告)日：2007-04-10
申请号：US10495413
申请日：2002-11-13
申请人： Suleman Alihodzic , Daniele Andreotti , Andrea Berdik , Ilaria Bientinesi , Stefano Biondi , Manuela Ciraco , Federica Damiani , Marko Djerek , Miljenko Dumic , Vesna Erakovic , Antun Hutinec , Gorjana Lazarevski , Sergio Lociuro , Natasa Marsic , Zorica Marusic-Istuk , Stjepan Mutak , Alfredo Paio , Drazen Pavlovic , Anna Quaglia , Wolfgang Schoenfeld , Vlado Stimac , Jessica Tibasco
发明人： Suleman Alihodzic , Daniele Andreotti , Andrea Berdik , Ilaria Bientinesi , Stefano Biondi , Manuela Ciraco , Federica Damiani , Marko Djerek , Miljenko Dumic , Vesna Erakovic , Antun Hutinec , Gorjana Lazarevski , Sergio Lociuro , Natasa Marsic , Zorica Marusic-Istuk , Stjepan Mutak , Alfredo Paio , Drazen Pavlovic , Anna Quaglia , Wolfgang Schoenfeld , Vlado Stimac , Jessica Tibasco
CPC分类号： C07H17/08
摘要： The present invention relates to 14 or 15 membered macrolides substituted at the 4′ position of formula (I) and pharmaceutically acceptable salts and solvates thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body
摘要翻译： 本发明涉及在式（I）的4'位取代的14或15元大环内酯及其药学上可接受的盐和溶剂化物，其制备方法及其在治疗或预防人体全身或局部细菌感染中的用途 或动物体
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