专利检索 ap:("Illumina Cambridge Limited" OR "Illumina Singapore Pte. Ltd." OR "Illumina, Inc." OR "Illumina Software, Inc.") AND inv:"Madushani Dharmarwardana" 第 1 页

1.

发明公开
COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING 审中-公开

公开(公告)号：US20230383342A1

公开(公告)日：2023-11-30

申请号：US18325610

申请日：2023-05-30

申请人： Illumina Cambridge Limited , Illumina Singapore Pte. Ltd. , Illumina, Inc. , Illumina Software, Inc.

发明人： Xiaolin Wu , Patrick McCauley , Madushani Dharmarwardana , Saurabh Nirantar , Misha Golynskiy , Xiangyuan Yang , Ramesh Neelakandan , Benedict Mackworth , Carole Anastasi , Aathavan Karunakaran , Gery M. Vessere , David Bracher

IPC分类号： C12Q1/6869 , G01N21/64

CPC分类号： C12Q1/6869 , G01N2021/6439 , G01N2021/6419 , G01N21/6428

摘要： Embodiments of the present disclosure relate to kits, compositions, and methods for nucleic acid sequencing, for example, two-channel nucleic acid sequencing by synthesis using blue and green light excitation. In particular, unlabeled nucleotides for incorporation may be used in conjunction with affinity reagents containing detectable labels excitable by blue and/or green lights, for specific binding to each type of nucleotides incorporated.