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10 条记录 (耗时 0.03 秒)

    Method of overproduction of polyhydroxybutyrate
    1.
    发明授权
    Method of overproduction of polyhydroxybutyrate 有权
    聚羟基丁酸酯过量生产的方法

    公开(公告)号：US07771964B2

    公开(公告)日：2010-08-10

    申请号：US10998473

    申请日：2004-11-29

    申请人： In Gyu Kim ,  Il Lae Jung ,  Hyo Kook Park ,  Kug Chan Kim ,  Byung Ho Choi

    发明人： In Gyu Kim ,  Il Lae Jung ,  Hyo Kook Park ,  Kug Chan Kim ,  Byung Ho Choi

    IPC分类号： C12P1/00 ,  C12P7/00 ,  C12P7/02 ,  C12P7/18

    CPC分类号： C12P7/62

    摘要： The present invention relates to a recombinant Escherichia coli having phbCAB originated from Alcaligenes eutrophus and an overproduction method of polyhydroxyalkanoate using the same, more precisely, a recombinant Escherichia coli ‘MG1655/pTZ18U-PHB’ or ‘JIL938/pTZ18U-PHB’ having phbCAB originated from Alcaligenes eutrophus and an overproduction method of polyhydroxyalkanoate comprising the steps of preparing transformed Escherichia coli having phbCAB originated from Alcaligenes eutrophus, inoculating and culturing the cells (growth phase), inducing the production of polyhydroxyalkanoate in the recomibnant Escherichia coli (stationary phase and producing phase), and inducing the extracellular secretion of the polyhydroxyalkanoate from the recombinant Escherichia coli. The method of the present invention facilitates not only overproduction of polyhydroxyalkanoate such as polyhydroxybutyrate by a simple batch culture but also industrial use of biodegradable polyhydroxyalkanoate replacing conventional non-biodegradable plastics by its simple and easy fermentation, separation and purification process.

    摘要翻译： 本发明涉及具有源自嗜碱性杆菌的phbCAB的重组大肠杆菌，以及使用该重组大肠杆菌的具有phbCAB的重组大肠杆菌MG1655 / pTZ18U-PHB'或'JIL938 / pTZ18U-PHB'的多羟基链烷酸酯的过量产生方法 来自产碱杆菌属的富含嗜碱性细菌的产生方法和多羟基链烷酸酯的过量产生方法，包括以下步骤：制备具有源自产碱杆菌属细菌的phbCAB的转化大肠杆菌，接种和培养细胞（生长期），诱导在大肠杆菌（稳定期和生产阶段）中产生聚羟基链烷酸酯 ），并诱导来自重组大肠杆菌的聚羟基链烷酸酯的细胞外分泌。 本发明的方法不仅通过简单的分批培养而不仅过度生产聚羟基链烷酸酯如聚羟基丁酸酯，而且还通过其简单且容易的发酵，分离和纯化方法替代常规的不可生物降解的塑料来生产可降解的聚羟基链烷酸酯的工业应用。

    Method for enhancing chemical sensitivity or radiosensitivity of cancer cells by inhibiting expression of TSPYL5
    2.
    发明授权
    Method for enhancing chemical sensitivity or radiosensitivity of cancer cells by inhibiting expression of TSPYL5 有权
    通过抑制TSPYL5的表达来提高癌细胞的化学敏感性或放射敏感性的方法

    公开(公告)号：US08343940B2

    公开(公告)日：2013-01-01

    申请号：US12823035

    申请日：2010-06-24

    申请人： In Gyu Kim ,  Tae Lim Kim ,  Kug Chan Kim ,  Eun Jin Kim ,  So Yong Lee ,  Il Lae Jung

    发明人： In Gyu Kim ,  Tae Lim Kim ,  Kug Chan Kim ,  Eun Jin Kim ,  So Yong Lee ,  Il Lae Jung

    IPC分类号： C12N15/11 ,  C07H21/02 ,  C07H21/04

    CPC分类号： G01N33/5011 ,  G01N33/574

    摘要： Disclosed herein is a method for enhancing sensitivity of cancer cells to compounds or radiation by inhibiting the expression of testis-specific protein, Y-encoded like 5 (TSPYL5). More specifically, because methylation of TSPYL5 protein expressed in lung cancer cell line was inhibited to increase the expression level of the gene, resistance to stress such as radiation or anticancer agents was increased. Because the sensitivity of cancer cells to stress such as radiation or anticancer agents was increased by inhibiting the expression of the TSPYL5 gene to promote the apoptosis of the cells, an anticancer supplement agent containing an inhibitor of the expression or activity of the TSPYL5 gene of the present invention inhibits the growth of cancer cells and enhances the sensitivity to various stresses to maximize the apoptosis. Thus, when used in combination with radiotherapy or chemotherapy, the anticancer supplement agent may be used very usefully for anticancer treatment.

    摘要翻译： 本文公开了通过抑制Y编码的5（TSPYL5）的睾丸特异性蛋白质的表达来增强癌细胞对化合物或辐射的敏感性的方法。 更具体地说，由于在肺癌细胞系中表达的TSPYL5蛋白的甲基化被抑制以增加基因的表达水平，所以对抗应激性（如放射线或抗癌剂）的抗性增加。 因为通过抑制TSPYL5基因的表达以促进细胞凋亡来增加癌细胞对诸如放射线或抗癌剂之类的应激的敏感性，所以可以使用含有TSPYL5基因的表达或活性抑制剂的抗癌补充剂 本发明抑制癌细胞的生长并且增强对各种应激的敏感性以使细胞凋亡最大化。 因此，当与放射治疗或化疗组合使用时，抗癌补充剂可以非常有用地用于抗癌治疗。

    Knee bolster apparatus of vehicle
    3.
    发明申请
    Knee bolster apparatus of vehicle 审中-公开
    车辆膝盖枕式装置

    公开(公告)号：US20050067824A1

    公开(公告)日：2005-03-31

    申请号：US10750685

    申请日：2003-12-31

    申请人： In Gyu Kim

    发明人： In Gyu Kim

    IPC分类号： B62D25/08 ,  B60R21/02 ,  B60R21/045

    CPC分类号： B60R21/045

    摘要： A knee bolster apparatus comprises a knee bolster plate mounted on a instrument panel. A supporting frame transversely extends through an inner space of the instrument panel and includes a supporting bracket secured to the supporting frame and disposed to be opposite to the instrument panel. The supporting bracket is shaped as an “S” as a single body such that the supporting bracket is relatively light weight and improves the efficiency of production and the performance requirement regarding strength and buffering of an occupants knees.

    摘要翻译： 膝盖枕装置包括安装在仪表板上的膝垫板。 支撑框架横向延伸穿过仪表板的内部空间并且包括固定到支撑框架并且设置成与仪表板相对的支撑托架。 支撑托架被形成为“S”作为单个主体，使得支撑托架相对较轻，并且提高了生产效率以及关于乘员膝盖的强度和缓冲的性能要求。

    Tray apparatus
    4.
    发明申请
    Tray apparatus 有权
    托盘设备

    公开(公告)号：US20090289092A1

    公开(公告)日：2009-11-26

    申请号：US12325130

    申请日：2008-11-28

    申请人： Jong Sun LEE ,  Yang Gi Lee ,  Tae Hoon Song ,  In Gyu Kim ,  Jin Wan Park ,  Yong Gu Kang

    发明人： Jong Sun LEE ,  Yang Gi Lee ,  Tae Hoon Song ,  In Gyu Kim ,  Jin Wan Park ,  Yong Gu Kang

    IPC分类号： B60R7/06

    CPC分类号： B60R7/06 ,  B60R7/04

    摘要： A tray apparatus may include a housing, a tray slidably accommodated in the housing to be opened or closed, a rotary lock pivotally coupled to the housing at a hinge portion of the rotary lock and locking the tray to the housing when external shock is applied to the tray beyond a predetermined value, wherein a center of gravity of the rotary lock is positioned above the hinge portion, and a holding unit for holding the rotary lock in a normal state so that the rotary lock maintains an original position thereof.

    摘要翻译： 托盘装置可以包括壳体，可滑动地容纳在壳体中以被打开或关闭的托盘，在旋转锁的铰链部分处枢转地联接到壳体的旋转锁，并且当外部冲击施加到托架装置时将托盘锁定到壳体 所述托盘超过预定值，其中所述旋转锁的重心位于所述铰链部分的上方，以及保持单元，用于将所述旋转锁保持在正常状态，使得所述旋转锁保持其初始位置。

    Fan for air conditioner
    7.
    发明申请
    Fan for air conditioner 有权
    风机风机

    公开(公告)号：US20080084140A1

    公开(公告)日：2008-04-10

    申请号：US11547783

    申请日：2004-08-19

    申请人： In Gyu Kim

    发明人： In Gyu Kim

    IPC分类号： H02K9/06 ,  H02K7/00 ,  F04B17/00

    CPC分类号： H02K7/14 ,  F04D25/064 ,  F04D25/0646 ,  F04D29/668 ,  F24F1/0007 ,  F24F1/0018 ,  F24F1/0022 ,  H02K3/522

    摘要： Fan apparatus for an air conditioner including a fan (50), a shaft (68) coupled to the fan (50), a rotor (60) for transmission of driving force to the shaft (68) for rotating the fan (50), a stator (65) on an inside of the rotor (60) to form a BLDC motor together with the rotor (60), and a fan housing (40) for enclosing the fan (50), thereby reducing noise and enhancing fan (50) efficiency.

    摘要翻译： 一种用于空调的风扇装置，包括风扇（50），连接到风扇（50）的轴（68），用于将驱动力传递到用于使风扇（50）旋转的轴（68）的转子（60） 与转子（60）一起形成BLDC电动机的转子（60）内部的定子（65），以及用于封闭风扇（50）的风扇壳体（40），从而减少风扇（50 ）效率。

    Tray apparatus
    9.
    发明授权
    Tray apparatus 有权
    托盘设备

    公开(公告)号：US08109424B2

    公开(公告)日：2012-02-07

    申请号：US12325130

    申请日：2008-11-28

    申请人： Jong Sun Lee ,  Yang Gi Lee ,  Tae Hoon Song ,  In Gyu Kim ,  Jin Wan Park ,  Yong Gu Kang

    发明人： Jong Sun Lee ,  Yang Gi Lee ,  Tae Hoon Song ,  In Gyu Kim ,  Jin Wan Park ,  Yong Gu Kang

    IPC分类号： B60R7/06

    CPC分类号： B60R7/06 ,  B60R7/04

    摘要： A tray apparatus may include a housing, a tray slidably accommodated in the housing to be opened or closed, a rotary lock pivotally coupled to the housing at a hinge portion of the rotary lock and locking the tray to the housing when external shock is applied to the tray beyond a predetermined value, wherein a center of gravity of the rotary lock is positioned above the hinge portion, and a holding unit for holding the rotary lock in a normal state so that the rotary lock maintains an original position thereof.

    摘要翻译： 托盘装置可以包括壳体，可滑动地容纳在壳体中以被打开或关闭的托盘，在旋转锁的铰链部分处枢转地联接到壳体的旋转锁，并且当外部冲击施加到托架装置时将托盘锁定到壳体 所述托盘超过预定值，其中所述旋转锁的重心位于所述铰链部分的上方，以及保持单元，用于将所述旋转锁保持在正常状态，使得所述旋转锁保持其初始位置。