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    Sealant forming apparatus, sealant forming method, and method of manufacturing liquid crystal display device using the same
    3.
    发明授权
    Sealant forming apparatus, sealant forming method, and method of manufacturing liquid crystal display device using the same 有权
    密封剂形成装置，密封剂形成方法以及使用其的液晶显示装置的制造方法

    公开(公告)号：US09433965B2

    公开(公告)日：2016-09-06

    申请号：US12793166

    申请日：2010-06-03

    Applicant: Hae Joon Son ,  In Kyu Lee

    Inventor： Hae Joon Son ,  In Kyu Lee

    IPC: B05C11/10 ,  B05C5/02 ,  G02F1/1339

    CPC classification number: B05C11/1002 ,  B05C5/02 ,  G02F1/1339

    Abstract: A sealant forming device, a sealant forming method and a method for manufacturing a liquid crystal display device using the same are disclosed. According to the present invention, a sealant coagulated in a nozzle can be minimized or prevented by performing an instantaneous suction process. A sealant forming device includes a dispenser including a syringe, and a nozzle connected to a lower end of the syringe to discharge a sealant therethrough; a dispensing tube connected to the syringe to apply a pressure to the syringe; and an instantaneous suction tube connected to the syringe to extract the sealant remaining in the nozzle after discharging the sealant.

    Abstract translation: 公开了一种密封剂形成装置，密封剂形成方法和使用其的液晶显示装置的制造方法。 根据本发明，通过进行瞬时抽吸处理，可以使在喷嘴中凝结的密封剂最小化或防止。 密封剂形成装置包括：分配器，其包括注射器;以及喷嘴，其连接到所述注射器的下端，以通过其排出密封剂; 连接到注射器以向注射器施加压力的分配管; 以及连接到注射器的瞬时吸入管，以在排出密封剂之后提取残留在喷嘴中的密封剂。

    Sealant forming apparatus, sealant forming method, and method of manufacturing liquid crystal display device using the same
    4.
    发明申请
    Sealant forming apparatus, sealant forming method, and method of manufacturing liquid crystal display device using the same 有权
    密封剂形成装置，密封剂形成方法以及使用其的液晶显示装置的制造方法

    公开(公告)号：US20070151512A1

    公开(公告)日：2007-07-05

    申请号：US11478346

    申请日：2006-06-30

    Applicant: Hae Joon Son ,  In Kyu Lee

    Inventor： Hae Joon Son ,  In Kyu Lee

    IPC: B05C5/00 ,  B05B15/02

    CPC classification number: B05C11/1002 ,  B05C5/02 ,  G02F1/1339

    Abstract: A sealant forming device, a sealant forming method and a method for manufacturing a liquid crystal display device using the same are disclosed. According to the present invention, a sealant coagulated in a nozzle can be minimized or prevented by performing an instantaneous suction process. A sealant forming device includes a dispenser including a syringe, and a nozzle connected to a lower end of the syringe to discharge a sealant therethrough; a dispensing tube connected to the syringe to apply a pressure to the syringe; and an instantaneous suction tube connected to the syringe to extract the sealant remaining in the nozzle after discharging the sealant.

    Abstract translation: 公开了一种密封剂形成装置，密封剂形成方法和使用其的液晶显示装置的制造方法。 根据本发明，通过进行瞬时抽吸处理，可以使在喷嘴中凝结的密封剂最小化或防止。 密封剂形成装置包括：分配器，其包括注射器;以及喷嘴，其连接到所述注射器的下端，以通过其排出密封剂; 连接到注射器以向注射器施加压力的分配管; 以及连接到注射器的瞬时吸入管，以在排出密封剂之后提取残留在喷嘴中的密封剂。

    Processes for the preparation of cephalosporin derivatives
    5.
    发明申请
    Processes for the preparation of cephalosporin derivatives 有权
    制备头孢菌素衍生物的方法

    公开(公告)号：US20070083042A1

    公开(公告)日：2007-04-12

    申请号：US10577551

    申请日：2004-10-30

    Applicant: Dae Seo ,  In Hwa Chung ,  Ki Bong Lee ,  In Kyu Lee

    Inventor： Dae Seo ,  In Hwa Chung ,  Ki Bong Lee ,  In Kyu Lee

    IPC: C07D501/00

    CPC classification number: C07D501/00 ,  Y02P20/55

    Abstract: Provided is a process for preparing a compound of formula 1 or its salt. The process includes reacting a compound of formula 4 with acetaldehyde in a mixed solvent including water, isopropanol, and methylenechloride in a volume ratio of 1:3-6:11-14 in the presence of a first base to stereospecifically prepare a compound of formula 3 and reacting the compound of the formula 3 with an anhydrous compound of formula 2 in the presence of a second base.

    Abstract translation: 提供制备式1化合物或其盐的方法。 该方法包括在第一碱存在下，使体积比为1:3-6:11〜14的式4化合物与乙醛在包括水，异丙醇和二氯甲烷的混合溶剂中反应，以立体选择性地制备式 3并在第二碱的存在下使式3的化合物与式2的无水化合物反应。

    Sealant forming apparatus, sealant forming method, and method of manufacturing liquid crystal display device using the same
    6.
    发明授权
    Sealant forming apparatus, sealant forming method, and method of manufacturing liquid crystal display device using the same 有权
    密封剂形成装置，密封剂形成方法以及使用其的液晶显示装置的制造方法

    公开(公告)号：US07748342B2

    公开(公告)日：2010-07-06

    申请号：US11478346

    申请日：2006-06-30

    Applicant: Hae Joon Son ,  In Kyu Lee

    Inventor： Hae Joon Son ,  In Kyu Lee

    IPC: B05C5/00 ,  B05C11/00

    CPC classification number: B05C11/1002 ,  B05C5/02 ,  G02F1/1339

    Abstract: A sealant forming device, a sealant forming method and a method for manufacturing a liquid crystal display device using the same are disclosed. According to the present invention, a sealant coagulated in a nozzle can be minimized or prevented by performing an instantaneous suction process. A sealant forming device includes a dispenser including a syringe, and a nozzle connected to a lower end of the syringe to discharge a sealant therethrough; a dispensing tube connected to the syringe to apply a pressure to the syringe; and an instantaneous suction tube connected to the syringe to extract the sealant remaining in the nozzle after discharging the sealant.

    Abstract translation: 公开了一种密封剂形成装置，密封剂形成方法和使用其的液晶显示装置的制造方法。 根据本发明，通过进行瞬时抽吸处理，可以使在喷嘴中凝结的密封剂最小化或防止。 密封剂形成装置包括：分配器，其包括注射器;以及喷嘴，其连接到所述注射器的下端，以通过其排出密封剂; 连接到注射器以向注射器施加压力的分配管; 以及连接到注射器的瞬时吸入管，以在排出密封剂之后提取残留在喷嘴中的密封剂。

    NOVEL USE OF DIMETHYLFUMARATE
    7.
    发明申请
    NOVEL USE OF DIMETHYLFUMARATE 审中-公开
    二甲基丙酸的新用途

    公开(公告)号：US20100324327A1

    公开(公告)日：2010-12-23

    申请号：US12677089

    申请日：2008-09-10

    Applicant: In Kyu Lee

    Inventor： In Kyu Lee

    IPC: C07C69/60

    CPC classification number: A61K31/225

    Abstract: Disclosed are a pharmaceutical composition for inhibiting vascular smooth muscle cell proliferation comprising dimethyl fumarate as an effective ingredient, use of dimethyl fumarate for inhibiting vascular smooth muscle cell proliferation, and a method of inhibiting vascular smooth muscle cell proliferation employing the same. Through the present invention, it was found that dimethyl fumarate could inhibit vascular smooth muscle cell proliferation by increasing the activity of AMPK. Accordingly, dimethyl fumarate can be usefully used as an effective ingredient of a medicine for inhibiting vascular smooth muscle cell proliferation.

    Abstract translation: 公开了一种用于抑制血管平滑肌细胞增殖的药物组合物，其包含富马酸二甲酯作为有效成分，使用富马酸二甲酯抑制血管平滑肌细胞增殖，以及使用该药物组合物抑制血管平滑肌细胞增殖的方法。 通过本发明，通过增加AMPK的活性，发现富马酸二甲酯可以抑制血管平滑肌细胞增殖。 因此，富马酸二甲酯可有效地用作抑制血管平滑肌细胞增殖的药物的有效成分。

    Processes for the preparation of cephalosporin derivatives
    8.
    发明授权
    Processes for the preparation of cephalosporin derivatives 有权
    制备头孢菌素衍生物的方法

    公开(公告)号：US07622577B2

    公开(公告)日：2009-11-24

    申请号：US10577551

    申请日：2004-10-30

    Applicant: Dae Won Seo ,  In Hwa Chung ,  Ki Bong Lee ,  In Kyu Lee

    Inventor： Dae Won Seo ,  In Hwa Chung ,  Ki Bong Lee ,  In Kyu Lee

    IPC: C07D501/22

    CPC classification number: C07D501/00 ,  Y02P20/55

    Abstract: Provided is a process for preparing a compound of formula 1 or its salt, which comprises reacting a compound represented by the following formula 4 with acetaldehyde in a mixed solvent comprising water, isopropanol, and methylenechloride in a volume ratio of 1:3-6:11-14 in the presence of a first base to stereospecifically prepare a compound represented by the following formula 3′; and reacting the compound of the formula 3′ with an anhydrous compound represented by the following formula 2 in the presence of a second base: wherein R1 is a hydrogen or an amino protecting group, R2 is a hydrogen or a carboxyl protecting group, and R3 is a hydrogen or an amino protecting group consisting of phenylacetyl group, wherein when R3 is a phenylacetyl group, R2 is not a hydrogen in formula 3′; and wherein, when at least one of R2 and R3 is a protecting group, all such protecting groups are removed from formula 3′, thereby producing a compound represented by formula 6 prior to reacting it with the compound of formula 2.

    Abstract translation: 本发明提供制备式1化合物或其盐的方法，该方法包括使下式4表示的化合物与乙醛在含有水，异丙醇和二氯甲烷的混合溶剂中以体积比为1:3-6:3的比例反应， 11-14在第一碱的存在下，立体选择性地制备由下式3'表示的化合物; 并使式3'化合物与下式2表示的无水化合物在第二碱存在下反应：其中R1是氢或氨基保护基，R2是氢或羧基保护基，R3是 是由苯乙酰基组成的氢或氨基保护基，其中当R3是苯乙酰基时，R2不是式3'中的氢; 并且其中当R 2和R 3中的至少一个是保护基时，从式3'中除去所有这些保护基，从而在与式2化合物反应之前制备由式6表示的化合物。

    NOVEL USE OF SCOPARONE
    10.
    发明申请
    NOVEL USE OF SCOPARONE 审中-公开
    SCOPARONE的新用途

    公开(公告)号：US20110015410A1

    公开(公告)日：2011-01-20

    申请号：US12677092

    申请日：2008-09-10

    Applicant: In Kyu Lee

    Inventor： In Kyu Lee

    IPC: C07D311/16

    CPC classification number: A61K31/37

    Abstract: Disclosed herein are a pharmaceutical composition for inhibiting the proliferation of vascular smooth muscle cells, which contains scoparone as an active ingredient, the use of scoparone for inhibiting the proliferation of vascular smooth muscle cells and a method for inhibiting the proliferation of vascular smooth muscle cells using scoparone. According to the disclosed invention, it has been found that scoparone can inhibit the proliferation of vascular smooth muscle cells by increasing the activity of AMPK. Accordingly, scoparone can be advantageously used as an active ingredient' in drugs for inhibiting the proliferation of vascular smooth muscle cells, particularly preventing or treating blood vessel restenosis.

    Abstract translation: 本文公开了一种用于抑制血管平滑肌细胞增殖的药物组合物，其含有作为活性成分的角叉菜酮，使用角叉菜胶抑制血管平滑肌细胞的增殖，以及抑制血管平滑肌细胞增殖的方法 角叉菜胶 根据所公开的发明，已经发现，通过增加AMPK的活性，角叉菜胶可以抑制血管平滑肌细胞的增殖。 因此，作为抑制血管平滑肌细胞增殖的药物，特别是预防或治疗血管再狭窄，可以有利地使用角叉菜胶作为活性成分。

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