公开(公告)号：US10821148B2

公开(公告)日：2020-11-03

申请号：US15416391

申请日：2017-01-26

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Kuei Huang ,  I-Horng Pan ,  Ying-Fei Tsai ,  I-Huang Lu ,  Chu-Hsun Lu ,  Shu-Fang Wen ,  Zong-Keng Kuo ,  Shu-Jiau Chiou

IPC: A61K36/00 ,  A61K36/75 ,  A61K31/395 ,  A61K31/366 ,  A61K31/37 ,  A61K31/4015 ,  A61K31/404

Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).

公开(公告)号：US11510957B2

公开(公告)日：2022-11-29

申请号：US16698502

申请日：2019-11-27

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Kuei Huang ,  I-Horng Pan ,  Meng-Nan Lin ,  Jir-Mehng Lo ,  Jennline Sheu ,  Pei-Ru Liau ,  Yi-Cheng Cheng ,  Pei-Hsin Lin

IPC: A61K36/00 ,  A61K36/9064 ,  A61K31/11 ,  A61K9/00

Abstract: A method of treating or alleviating autoimmune-related diseases is provided. The method comprises administering a pharmaceutical composition to a subject in need thereof. Moreover, the pharmaceutical composition comprises an extract of Amomum tsao-ko as an effective ingredient and a pharmaceutically acceptable carrier or salt.

公开(公告)号：US09603882B2

公开(公告)日：2017-03-28

申请号：US14323719

申请日：2014-07-03

Applicant: Industrial Technology Research Institute

Inventor： I-Horng Pan ,  Shu-Fang Wen ,  Ming-Han Li ,  Hsin-Jan Yao ,  Hsin-Chieh Wu ,  I-Huang Lu ,  Joung-Liang Lan ,  Der-Yuan Chen ,  Chi-Chien Lin ,  Ching Lu

IPC: A61K36/06 ,  A61K36/07

CPC classification number: A61K36/07

Abstract: The disclosure provides a method for modulating Th17 cells, including: administering an Antrodia cinnamomea (also named Antrodia camphorata or Taiwanofungus camphoratus) extract to a subject in need thereof, wherein the Antrodia cinnamomea extract has an effect of modulating Th17 cells. The Antrodia cinnamomea extract may include a fruiting body extract of Antrodia cinnamomea or a mycelium extract of Antrodia cinnamomea.

公开(公告)号：US10987394B2

公开(公告)日：2021-04-27

申请号：US15852748

申请日：2017-12-22

Applicant: Industrial Technology Research Institute

Inventor： I-Horng Pan ,  Hsin-Jan Yao ,  Chu-Hsun Lu ,  Shu-Fang Wen ,  Po-Yao Hsu ,  Ming-Han Li ,  Kai-An Chuang ,  Chih-Hsuan Chang

IPC: A61K36/28 ,  A61K36/00 ,  A61K36/287 ,  A61K9/00 ,  A61P17/06 ,  A61P17/04

Abstract: The present disclosure provides a method for preparing an extract of Chrysanthemum morifolium with an effect of treating skin diseases, including: (a) performing an extraction procedure on Chrysanthemum morifolium with an extraction solvent to obtain an extract solution; and (b) adding at least one glycoside hydrolases to the extract solution to make an enzyme reaction occur to produce a precipitate, wherein the precipitate is the extract of Chrysanthemum morifolium with an effect of treating skin diseases.

公开(公告)号：US09682062B2

公开(公告)日：2017-06-20

申请号：US14133213

申请日：2013-12-18

Applicant: Industrial Technology Research Institute

Inventor： I-Horng Pan ,  Hsin-Jan Yao ,  Mei-Wei Lin ,  I-Huang Lu ,  Hsin-Chieh Wu ,  Hsiang-Wen Tseng ,  Ching-Huai Ko ,  Chun-Chung Wang ,  Zong-Keng Kuo ,  Shyh-Horng Lin ,  Yi-Cheng Cheng ,  Tien-Soung Tong

IPC: A61K36/15 ,  A61K36/185 ,  A61K31/365 ,  A61K36/14 ,  A61K31/7048

CPC classification number: A61K31/365 ,  A61K31/7048 ,  A61K36/14 ,  A61K2300/00

Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.