专利检索 ap:("Infinity Pharmaceuticals, Inc.") AND inv:"Charles W. Johannes" 第 1 页

1.

发明申请
ENZYMATIC TRANSAMINATION OF CYCLOPAMINE ANALOGS 有权
标题翻译：环糊精类似物的酶促转移

公开(公告)号：US20160177354A1

公开(公告)日：2016-06-23

申请号：US15054011

申请日：2016-02-25

申请人： Infinity Pharmaceuticals, Inc.

发明人： Brian C. Austad , Adilah Bahadoor , Jitendra D. Belani , Somarajannair Janardanannair , Sheldon L. Wallerstein , Gregg F. Keaney , Priscilla L. White , Charles W. Johannes

IPC分类号： C12P17/18

CPC分类号： C12P17/18 , C07D491/10 , C07D491/107

摘要： Provided are processes for the synthesis of amino analogues from ketone starting materials.

摘要翻译： 提供了从酮起始原料合成氨基类似物的方法。

2.

发明授权
Enzymatic transamination of cyclopamine analogs 有权

公开(公告)号：US09879293B2

公开(公告)日：2018-01-30

申请号：US15054011

申请日：2016-02-25

申请人： Infinity Pharmaceuticals, Inc.

发明人： Brian C. Austad , Adilah Bahadoor , Jitendra D. Belani , Somarajannair Janardanannair , Sheldon L. Wallerstein , Gregg F. Keaney , Priscilla L. White , Charles W. Johannes

IPC分类号： C12P17/18 , C07D491/10 , C07D491/107

CPC分类号： C12P17/18 , C07D491/10 , C07D491/107

摘要： The invention relates to the preparation of amino-cyclopamines by the enzymatic transamination of a corresponding keto-cyclopamines in the presence of a cofactor and an amino donor.