公开(公告)号：US20250145624A1

公开(公告)日：2025-05-08

申请号：US18837843

申请日：2023-02-17

Applicant: Insilico Medicine IP Limited

Inventor： Xiao DING ,  Fanye MENG ,  Feng REN ,  Yazhou WANG ,  Min ZHENG

IPC: C07D471/16 ,  A61K31/55 ,  C07D487/16

Abstract: Described herein are PKMYT1 (Myt1) inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with PKMYT1.

公开(公告)号：US20250136596A1

公开(公告)日：2025-05-01

申请号：US18837846

申请日：2023-02-17

Applicant: Insilico Medicine IP Limited

Inventor： Xiao DING ,  Yangguang LI ,  Yingtao LIU ,  Fanye MENG ,  Feng REN ,  Yazhou WANG ,  Min ZHENG

IPC: C07D471/04 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/497 ,  A61K31/4985 ,  A61K31/501 ,  A61K31/506 ,  A61K31/53 ,  A61K31/541 ,  C07D487/04 ,  C07D519/00

Abstract: Described herein are PKMYT1 (Myt1) inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with PKMYT1.