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公开(公告)号：US20240132465A1
公开(公告)日：2024-04-25
申请号：US18509658
申请日：2023-11-15
发明人： Chiachun CHEN , Xiao DING , Xiaosong LIU , Feng REN , Hailong WANG
IPC分类号： C07D401/04 , C07D239/95 , C07D403/04 , C07D471/04 , C07D487/04
CPC分类号： C07D401/04 , C07D239/95 , C07D403/04 , C07D471/04 , C07D487/04
摘要： Described herein are MAT2A inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with MAT2A.
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公开(公告)号：US20230192624A1
公开(公告)日：2023-06-22
申请号：US18107127
申请日：2023-02-08
发明人： Xiao DING , Jingjing PENG , Feng REN , Xiaoyu DING , Bogdan ZAGRIBELNYY , Yan A. IVANENKOV
IPC分类号： C07D233/96 , A61P31/14
CPC分类号： C07D233/96 , A61P31/14
摘要： Provided herein are compounds, pharmaceutical compositions, and methods for treating a SARS-CoV-2 infection.
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公开(公告)号：US20240067661A1
公开(公告)日：2024-02-29
申请号：US18240886
申请日：2023-08-31
IPC分类号： C07D519/00 , C07D471/04
CPC分类号： C07D519/00 , C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of anemia.
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公开(公告)号：US20240002406A1
公开(公告)日：2024-01-04
申请号：US18339362
申请日：2023-06-22
IPC分类号： C07D519/00 , C07D471/04
CPC分类号： C07D519/00 , C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of inflammatory bowel disease.
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公开(公告)号：US20240166608A1
公开(公告)日：2024-05-23
申请号：US18529689
申请日：2023-12-05
发明人： Xiao DING , Jinxin LIU , Feng REN , Jianfei WAN , Wei ZHU
IPC分类号： C07D231/56 , A61P35/00 , C07D209/44 , C07D215/14 , C07D401/04 , C07D403/08 , C07D471/04 , C07D487/04
CPC分类号： C07D231/56 , A61P35/00 , C07D209/44 , C07D215/14 , C07D401/04 , C07D403/08 , C07D471/04 , C07D487/04
摘要： The disclosure provides for compounds and methods for modulating or inhibiting TEAD. Further provided herein are pharmaceutical compositions comprising the TEAD inhibitors and methods of treatment using the TEAD inhibitors or the pharmaceutical compositions.
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公开(公告)号：US20230192723A1
公开(公告)日：2023-06-22
申请号：US18110261
申请日：2023-02-15
IPC分类号： C07D519/00 , C07D471/04
CPC分类号： C07D519/00 , C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of anemia.
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公开(公告)号：US20230192688A1
公开(公告)日：2023-06-22
申请号：US18110259
申请日：2023-02-15
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of inflammatory bowel disease.
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公开(公告)号：US20240116935A1
公开(公告)日：2024-04-11
申请号：US18507595
申请日：2023-11-13
发明人： Hongfu LU , Huaxing YU , Xiao DING , Feng REN
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Described herein are DGKalpha inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with DGKalpha.
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公开(公告)号：US20240051958A1
公开(公告)日：2024-02-15
申请号：US18486374
申请日：2023-10-13
发明人： Hongfu LU , Huaxing YU , Xiao DING , Feng REN
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Described herein are DGKalpha inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with DGKalpha.
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公开(公告)号：US20240025860A1
公开(公告)日：2024-01-25
申请号：US18339366
申请日：2023-06-22
发明人： Xiao DING , Jingjing PENG , Feng REN , Xiaoyu DING , Bogdan ZAGRIBELNYY , Yan A. IVANENKOV
IPC分类号： C07D233/96 , A61P31/14
CPC分类号： C07D233/96 , A61P31/14
摘要： Provided herein are compounds, pharmaceutical compositions, and methods for treating a SARS-CoV-2 infection.
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