公开(公告)号：US20250101019A1

公开(公告)日：2025-03-27

申请号：US18832564

申请日：2023-01-28

Applicant: Insilico Medicine IP Limited

Inventor： Xin CHENG ,  Yingtao LIU ,  Luoheng QIN ,  Feng REN ,  Huaxing YU

IPC: C07D471/04 ,  A61K31/437 ,  A61K31/444

Abstract: Described herein are ENPP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with ENPP1.

公开(公告)号：US20240116935A1

公开(公告)日：2024-04-11

申请号：US18507595

申请日：2023-11-13

Applicant: Insilico Medicine IP Limited

Inventor： Hongfu LU ,  Huaxing YU ,  Xiao DING ,  Feng REN

IPC: C07D471/04

CPC classification number: C07D471/04

Abstract: Described herein are DGKalpha inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with DGKalpha.

公开(公告)号：US20240051958A1

公开(公告)日：2024-02-15

申请号：US18486374

申请日：2023-10-13

Applicant: Insilico Medicine IP Limited

Inventor： Hongfu LU ,  Huaxing YU ,  Xiao DING ,  Feng REN

IPC: C07D471/04

CPC classification number: C07D471/04

Abstract: Described herein are DGKalpha inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with DGKalpha.