公开(公告)号：US20160096936A1

公开(公告)日：2016-04-07

申请号：US14875818

申请日：2015-10-06

申请人： Interface Biologics Inc.

发明人： Jamie Robert SWENOR ,  Mark A. STEEDMAN ,  Sanjoy MULLICK

IPC分类号： C08J5/18 ,  B32B27/32 ,  B65D65/38 ,  B32B27/18 ,  B65B55/04 ,  B32B27/08 ,  B32B27/40

CPC分类号： B65D65/38 ,  B32B27/08 ,  B32B27/18 ,  B32B27/302 ,  B32B27/304 ,  B32B27/306 ,  B32B27/32 ,  B32B27/325 ,  B32B27/34 ,  B32B27/36 ,  B32B27/40 ,  B32B2250/24 ,  B32B2270/00 ,  B32B2307/7246 ,  B32B2323/046 ,  B32B2439/00 ,  B32B2439/70 ,  B32B2439/80 ,  B65B55/04 ,  B65D65/40 ,  B65D2565/387 ,  C08J7/047 ,  C08J2323/06 ,  C08J2475/04 ,  Y02W30/806

摘要： The invention features a packaging material including a film having a barrier layer formed from an admixture containing a base polymer and a surface-modifying macromolecule. The invention also features containers made from the packaging materials and methods of storing a good.

摘要翻译： 本发明的特征在于一种包装材料，其包括具有由含有基础聚合物和表面改性大分子的混合物形成的阻隔层的膜。 本发明还具有由包装材料制成的容器和储存良好的方法。

公开(公告)号：US20190142317A1

公开(公告)日：2019-05-16

申请号：US16300404

申请日：2017-05-10

申请人： Interface Biologics, Inc.

发明人： Mark A. STEEDMAN ,  Jeannette HO ,  Jamie Robert SWENOR ,  Sanjoy MULLICK

IPC分类号： A61B5/1486 ,  A61B5/145 ,  A61L31/16 ,  A61L31/12 ,  A61L31/14 ,  C08G18/48 ,  C08G18/62 ,  C08G18/44 ,  C08G18/42 ,  C08G18/73 ,  C08G18/75 ,  C08G18/76 ,  C08G18/24 ,  C08G18/22

摘要： Disclosed are implantable glucose sensors having a biostable surface. The implantable glucose sensor includes a glucose detector and an enclosure defining a boundary between an internal space and an external space. The enclosure includes a semipermeable biointerface film containing a base polymer and a biostabilizing additive. The semipermeable biointerface film has a biostable surface and is permeable to glucose. The working electrode is disposed inside the internal space, and the biostable surface faces the external space or faces both the internal and the external spaces. Also disclosed are methods of preparation of the semipermeable biointerface films adapted for use in the implantable glucose sensors. Further, disclosed are methods of monitoring glucose levels in a subject through the use of an implantable glucose sensor. The implantable glucose sensor may be an implantable electrochemical glucose sensor, in which the glucose detector is a working electrode. Alternatively, the implantable glucose sensor may be an implantable optical glucose sensor, in which the glucose detector is a glucose recognition element including a glucose-binding fluorophore.