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公开(公告)号：US10195311B2
公开(公告)日：2019-02-05
申请号：US14532711
申请日：2014-11-04
Applicant: Interface Biologics, Inc.
Inventor： Roseita Esfand , J. Paul Santerre , Sylvia Tjahyadi , Bernadette Ilagan
IPC: A61L29/16 , A61M25/10 , A61L29/08 , A61K31/337 , A61K31/436 , A61L31/10 , A61L31/16 , C08G65/00 , C08L71/02 , A61K47/34 , A61K47/60 , A61K47/59 , A61K47/69
Abstract: The invention relates to oligofluorinated coatings and their use in drag delivery. The oligofluorinated coatings are compositions comprising formula (XVII). These coatings are used in a method of delivering a biologically active agent to a tissue surface in a mammalian tissue. This method occurs by contacting the surface with the coating including an oligofluorinated oligomer and a biologically active agent wherein the coating resides on the tissue surface and release the biologically active agent to the tissue surface.
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公开(公告)号：US10039864B2
公开(公告)日：2018-08-07
申请号：US15373138
申请日：2016-12-08
Applicant: Interface Biologics, Inc.
Inventor： Roseita Esfand , J. Paul Santerre , Mark J. Ernsting , H. Hung Pham , Vivian Z. Wang , Meilin Yang
IPC: A61L31/10 , C09D175/16 , A61L31/04 , C09D167/07 , C08G18/10 , C08J5/18 , C08G63/06 , C08G18/28 , C08G18/48 , C08G18/67 , C08G18/77 , C08G63/91 , C09D167/04
Abstract: The invention features oligofluorinated cross-linked polymers and their use in the manufacture of articles and coating surfaces.
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公开(公告)号：US20160228632A1
公开(公告)日：2016-08-11
申请号：US15132846
申请日：2016-04-19
Applicant: Interface Biologics Inc.
Inventor： Sanjoy MULLICK , Weilun CHANG , Hanje CHEN , Mark A. STEEDMAN , Roseita ESFAND
CPC classification number: A61M1/3673 , A61L33/062 , A61M1/3672 , A61M2202/0413 , B01D63/022 , B01D63/023 , B01D67/0093 , B01D69/02 , B01D69/08 , B01D69/087 , B01D71/44 , B01D71/68 , B01D2323/30 , B01D2323/36 , B29C47/00 , B29C47/0014 , B29C47/0026 , B29L2023/00 , B29L2031/731
Abstract: The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.
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公开(公告)号：US09206283B1
公开(公告)日：2015-12-08
申请号：US14210687
申请日：2014-03-14
Applicant: Interface Biologics Inc. , AngioDynamics, Inc.
Inventor： J. Paul Santerre , Jeannette Ho , Alexandra Piotrowicz , Roseita Esfand , Raymond Lareau , Benjamin Bell
CPC classification number: A61L29/049 , A61L29/06 , C08G18/10 , C08G18/4825 , C08G18/485 , C08G18/73 , C08G18/831 , C08L75/04 , C09D175/04 , C08G18/2885
Abstract: The invention relates to admixtures of thermoplastic polyurethane base polymers that resist surface dulling and fluorinated additives and their use in the manufacture of articles, such as medical devices. For example, the admixtures of the invention are useful in the manufacture of blood dwelling medical devices, such as catheters.
Abstract translation: 本发明涉及抗表面钝化和氟化添加剂的热塑性聚氨酯基础聚合物的混合物及其在制造诸如医疗装置的制品中的用途。 例如，本发明的混合物可用于制造诸如导管的血液住院医疗装置。
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5.发明申请THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF 有权热稳定的微生物和基于异氰酸酯的表面改性大分子及其用途公开(公告)号：US20150025198A1
公开(公告)日：2015-01-22
申请号：US14188441
申请日：2014-02-24
Applicant: Interface Biologics Inc.
Inventor： Sanjoy MULLICK , Weilun CHANG , Alexandra PIOTROWICZ , Jeannette HO , Richard WITMEYER
CPC classification number: C08G18/714 , C08G18/227 , C08G18/2885 , C08G18/44 , C08G18/6208 , C08G18/755 , C08G18/7831 , C08G18/791 , C08G18/792 , C08G18/8087 , C08L27/06 , C08L75/04 , C08L77/00 , C08L81/06 , C08L83/04 , C08L2205/025 , Y10T428/139
Abstract: The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties.
Abstract translation: 本发明涉及具有高降解温度的表面改性大分子（SMM）及其在制造由需要高温处理的基础聚合物制成的制品中的用途。 表面改性剂与基础聚合物混合以赋予醇和拒水性。
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Patent Agency Ranking
公开(公告)号：US20170340781A1
公开(公告)日：2017-11-30
申请号：US15373138
申请日：2016-12-08
Applicant: Interface Biologics, Inc.
Inventor： Roseita ESFAND , J. Paul SANTERRE , Mark J. ERNSTING , H. Hung PHAM , Vivian Z. WANG , Meilin YANG
IPC: A61L31/10 , A61L31/04 , C09D167/04 , C09D167/07 , C08G18/10 , C08G18/48 , C08J5/18 , C08G63/91 , C08G63/06 , C08G18/77 , C08G18/67 , C09D175/16 , C08G18/28
CPC classification number: A61L31/10 , A61L31/04 , C08G18/10 , C08G18/2885 , C08G18/4854 , C08G18/672 , C08G18/771 , C08G63/06 , C08G63/912 , C08J5/18 , C08J2367/04 , C08J2367/07 , C08J2371/02 , C09D167/04 , C09D167/07 , C09D175/16
Abstract: The invention features oligofluorinated cross-linked polymers and their use in the manufacture of articles and coating surfaces.
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7.发明授权公开(公告)号：US09751972B2
公开(公告)日：2017-09-05
申请号：US14188441
申请日：2014-02-24
Applicant: Interface Biologics Inc.
Inventor： Sanjoy Mullick , Weilun Chang , Alexandra Piotrowicz , Jeannette Ho , Richard Witmeyer
IPC: C08G18/71 , C08G18/22 , C08G18/28 , C08G18/44 , C08G18/62 , C08G18/75 , C08G18/78 , C08G18/79 , C08G18/80 , C08L27/06 , C08L75/04 , C08L77/00 , C08L81/06 , C08L83/04
CPC classification number: C08G18/714 , C08G18/227 , C08G18/2885 , C08G18/44 , C08G18/6208 , C08G18/755 , C08G18/7831 , C08G18/791 , C08G18/792 , C08G18/8087 , C08L27/06 , C08L75/04 , C08L77/00 , C08L81/06 , C08L83/04 , C08L2205/025 , Y10T428/139
Abstract: The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties.
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公开(公告)号：US09687597B2
公开(公告)日：2017-06-27
申请号：US15132846
申请日：2016-04-19
Applicant: Interface Biologics Inc.
Inventor： Sanjoy Mullick , Weilun Chang , Hanje Chen , Mark A. Steedman , Roseita Esfand
IPC: A61M1/36 , B01D63/02 , A61L33/06 , F16L11/04 , B01D67/00 , B01D69/02 , B01D69/08 , B01D71/44 , B01D71/68 , B29C47/00 , B29L23/00 , B29L31/00
CPC classification number: A61M1/3673 , A61L33/062 , A61M1/3672 , A61M2202/0413 , B01D63/022 , B01D63/023 , B01D67/0093 , B01D69/02 , B01D69/08 , B01D69/087 , B01D71/44 , B01D71/68 , B01D2323/30 , B01D2323/36 , B29C47/00 , B29C47/0014 , B29C47/0026 , B29L2023/00 , B29L2031/731
Abstract: The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.
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公开(公告)号：US20150283304A1
公开(公告)日：2015-10-08
申请号：US14532711
申请日：2014-11-04
Applicant: Interface Biologics, Inc.
Inventor： Roseita ESFAND , J. Paul Santerre , Sylvia Tjahyadi , Bernadette Ilagan
CPC classification number: A61L29/16 , A61K31/337 , A61K31/436 , A61K47/34 , A61K47/59 , A61K47/60 , A61K47/6957 , A61L29/085 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61M25/10 , A61M2025/1045 , A61M2025/105 , C08G65/007 , C08L71/02 , C08L2203/02 , C08L27/12
Abstract: The invention relates to oligofluorinated coatings and their use in drag delivery. The oligofluorinated coatings are compositions comprising formula (XVII). These coatings are used in a method of delivering a biologically active agent to a tissue surface in a mammalian tissue. This method occurs by contacting the surface with the coating including an oligofluorinated oligomer and a biologically active agent wherein the coating resides on the tissue surface and release the biologically active agent to the tissue surface.
Abstract translation: 本发明涉及少氟涂料及其在拖曳递送中的用途。 低聚氟化涂料是包含式（XVII）的组合物。 这些涂层用于将生物活性剂递送至哺乳动物组织中的组织表面的方法。 该方法通过使表面与包含低聚氟化低聚物和生物活性剂的涂层接触而发生，其中涂层位于组织表面上并将生物活性剂释放到组织表面。
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公开(公告)号：US20150008179A1
公开(公告)日：2015-01-08
申请号：US14491324
申请日：2014-09-19
Applicant: Interface Biologics Inc.
Inventor： Sanjoy MULLICK , Weilun CHANG , Hanje CHEN , Mark A. STEEDMAN , Roseita ESFAND
CPC classification number: A61M1/3673 , A61L33/062 , A61M1/3672 , A61M2202/0413 , B01D63/022 , B01D63/023 , B01D67/0093 , B01D69/02 , B01D69/08 , B01D69/087 , B01D71/44 , B01D71/68 , B01D2323/30 , B01D2323/36 , B29C47/00 , B29C47/0014 , B29C47/0026 , B29L2023/00 , B29L2031/731
Abstract: The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.
Abstract translation: 本发明涉及体外血液回路及其组分（例如，中空纤维膜，灌封束和血液管），包括0.005％至10％（w / w）的表面改性大分子。 体外血液回路具有抗血栓形成的表面，可用于血液透析，血液透析，血液透析滤过，血液浓缩，血氧合和相关用途。
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