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公开(公告)号：US20100261688A1
公开(公告)日：2010-10-14
申请号：US12739873
申请日：2008-11-12
申请人： Iris Heep , Hans-Juergen Hamann , Sabine Koelling , Gert Daube , Klaus-Juergen Steffens , Rolf Daniels
发明人： Iris Heep , Hans-Juergen Hamann , Sabine Koelling , Gert Daube , Klaus-Juergen Steffens , Rolf Daniels
IPC分类号： A61K31/573 , A61K31/496 , A61K31/437 , A61K31/5395 , A61K31/53 , A61P31/00 , A61P33/00
CPC分类号： A61K9/10 , A61K31/44 , A61K31/47 , A61K31/53 , A61K31/545 , A61K31/7034 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/44 , A61K2300/00
摘要： The invention relates to a stabilization of fluid oil-based suspensions comprising a hydrophobic silica, and medicaments based on such suspensions.
摘要翻译： 本发明涉及包含疏水性二氧化硅的流体油基悬浮液的稳定化和基于这种悬浮液的药物。
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公开(公告)号：US09095511B2
公开(公告)日：2015-08-04
申请号：US12739873
申请日：2008-11-12
申请人： Iris Heep , Hans-Juergen Hamann , Sabine Koelling , Gert Daube , Klaus-Juergen Steffens , Rolf Daniels
发明人： Iris Heep , Hans-Juergen Hamann , Sabine Koelling , Gert Daube , Klaus-Juergen Steffens , Rolf Daniels
IPC分类号： A61K9/10 , A61K31/44 , A61K31/47 , A61K31/545 , A61K31/7034 , A61K47/10 , A61K47/44 , A61K47/12 , A61K47/26 , A61K45/06 , A61K31/53 , A61K47/02 , A61K47/14
CPC分类号： A61K9/10 , A61K31/44 , A61K31/47 , A61K31/53 , A61K31/545 , A61K31/7034 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/44 , A61K2300/00
摘要： The invention relates to a stabilization of fluid oil-based suspensions comprising a hydrophobic silica, and medicaments based on such suspensions.
摘要翻译： 本发明涉及包含疏水性二氧化硅的流体油基悬浮液的稳定化和基于这种悬浮液的药物。
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公开(公告)号：US20100009979A1
公开(公告)日：2010-01-14
申请号：US12280448
申请日：2007-02-23
IPC分类号： A61K31/5365 , A61K31/437 , A61K31/497 , C07D273/04 , C07D471/04 , C07D401/04 , A61P31/00 , A61P31/04
CPC分类号： A61K9/0019 , A61K31/47 , A61K47/02 , A61K47/186
摘要： The invention relates to the use of quaternary ammonium compounds for preventing precipitations of fluoroquinolones from their solutions and to stable, tolerated pharmaceuticals which are particularly suitable for parenteral use and which contain, in dissolved form, a fluoroquinolone and a quaternary ammonium compound.
摘要翻译： 本发明涉及季铵化合物用于防止氟喹诺酮从其溶液中沉淀出来的药物，以及特别适用于肠胃外使用的稳定的，耐受的药物，并且以溶解形式含有氟喹诺酮和季铵化合物。
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公开(公告)号：US20130197006A1
公开(公告)日：2013-08-01
申请号：US13878901
申请日：2011-10-11
IPC分类号： A61K9/00
CPC分类号： A61K9/0056 , A61K9/2018 , A61K9/2022 , A61K9/2054 , A61K9/2059
摘要： The present invention generally relates to soft chewables, especially suitable for delivering active ingredients to animals and processes for the preparation thereof. In various embodiments, the soft chewable comprises a pharmaceutically effective amount of at least one active ingredient, a flavoring agent, a disintegrant a humectant, an antioxidant, a preservative, and water. In accordance with preferred embodiments, the soft chewable is essentially free of starch, oil glycols, waxes, and soy products.
摘要翻译： 本发明一般涉及软质咀嚼物，特别适用于将活性成分输送给动物及其制备方法。 在各种实施方案中，软咀嚼物包含药学上有效量的至少一种活性成分，调味剂，崩解剂，湿润剂，抗氧化剂，防腐剂和水。 根据优选实施方案，软咀嚼基本上不含淀粉，油二醇，蜡和大豆制品。
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公开(公告)号：US07763583B2
公开(公告)日：2010-07-27
申请号：US11451676
申请日：2006-06-13
申请人： Venkata-Rangarao Kanikanti , Thomas Bach , Gertraut Altreuther , Michael Traeubel , Hans-Juergen Hamann
发明人： Venkata-Rangarao Kanikanti , Thomas Bach , Gertraut Altreuther , Michael Traeubel , Hans-Juergen Hamann
IPC分类号： A61K38/12
CPC分类号： A61K9/0017 , A61K31/495 , A61K38/15
摘要： The present invention relates to transdermally applicable compositions comprising cyclic depsipeptides and/or praziquantel, and to their preparation and their use for controlling endoparasites.
摘要翻译： 本发明涉及包含环状缩肽和/或吡喹酮的透皮适用组合物及其制备及其用于控制内寄生虫的用途。
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公开(公告)号：US20100197571A1
公开(公告)日：2010-08-05
申请号：US12602002
申请日：2008-05-28
申请人： Venkata-Rangarao Kanikanti , Hans-Juergen Hamann , Peter Kleinebudde , Andrea Michalk , Claudia Reitz
发明人： Venkata-Rangarao Kanikanti , Hans-Juergen Hamann , Peter Kleinebudde , Andrea Michalk , Claudia Reitz
IPC分类号： A61K38/12 , A61K31/66 , A61K31/4985
CPC分类号： A61K9/0053 , A61K9/1617
摘要： The invention relates to extrudates comprising one or more pharmaceutically active substances, where the extrudates have a strand diameter of 0.5 mm or less, and to the use of these extrudates for the manufacture of medicaments.
摘要翻译： 本发明涉及包含一种或多种药物活性物质的挤出物，其中挤出物具有0.5mm或更小的股线直径，以及这些挤出物用于制造药物的用途。
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公开(公告)号：US09744127B2
公开(公告)日：2017-08-29
申请号：US13878901
申请日：2011-10-11
CPC分类号： A61K9/0056 , A61K9/2018 , A61K9/2022 , A61K9/2054 , A61K9/2059
摘要： The present invention generally relates to soft chewables, especially suitable for delivering active ingredients to animals and processes for the preparation thereof. In various embodiments, the soft chewable comprises a pharmaceutically effective amount of at least one active ingredient, a flavoring agent, a disintegrant, a humectant, an antioxidant, a preservative, and water. In accordance with preferred embodiments, the soft chewable is essentially free of starch, oil, glycols, waxes, and soy products.
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8.发明申请ANTIBODIES WHICH BIND SELECTIVELY TO HAIR OF ANIMALS AND AN ANTIBODY BASED DRUG DELIVERY SYSTEM FOR ANIMALS 审中-公开选择动物头发的抗体和基于抗体的动物药物递送系统公开(公告)号：US20110263826A1
公开(公告)日：2011-10-27
申请号：US12741036
申请日：2008-10-29
申请人： Stefan Hofmann , Hans-Juergen Hamann , Rainer Fischer , Stefan Schillberg , Simon Oliver Vogel , Helga Schinkel
发明人： Stefan Hofmann , Hans-Juergen Hamann , Rainer Fischer , Stefan Schillberg , Simon Oliver Vogel , Helga Schinkel
IPC分类号： C07K16/18
CPC分类号： C07K16/18 , A61K47/6843 , A61K47/6927 , B82Y5/00
摘要： The present invention provides antibodies which bind selectively to hair of animals and an antibody based drug delivery system in which a particular formulation can be directed to animal hair. This is driven by the need of increasing the effective period of therapeutics for animal ectoparasites treatment, reducing the toxicity of these drugs and improving their release profile
摘要翻译： 本发明提供了选择性结合动物毛发和基于抗体的药物递送系统的抗体，其中特定的制剂可以被引导到动物毛发上。 这是由于需要增加用于动物体外寄生虫治疗的治疗的有效期，降低这些药物的毒性并改善其释放曲线
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公开(公告)号：US20120034273A1
公开(公告)日：2012-02-09
申请号：US13132872
申请日：2009-11-24
CPC分类号： A61K31/196 , A61K9/145 , A61K9/146 , Y10T428/2982
摘要： The invention relates to extrudates containing at least one pharmaceutically active substance in the form of needles, wherein the ratio of the particle size of the needle-shaped pharmaceutically active substance to the strand diameter is at least 1:15, and the use of these extrudates for the production of medicaments.
摘要翻译： 本发明涉及含有至少一种针状药物活性物质的挤出物，其中针状药物活性物质的粒径与丝束直径之比至少为1:15，并且使用这些挤出物 用于生产药物。
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