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    Polymorph of 4-[3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6- quinolinecarboxamide and a process for the preparation of the same
    2.
    发明申请
    Polymorph of 4-[3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6- quinolinecarboxamide and a process for the preparation of the same 审中-公开
    4- [3-氯-4-（环丙基氨基羰基）氨基苯氧基] -7-甲氧基-6-喹啉甲酰胺的多晶型物及其制备方法

    公开(公告)号：US20070117842A1

    公开(公告)日：2007-05-24

    申请号：US10553927

    申请日：2004-04-22

    申请人： Itaru Arimoto ,  Kazuhiro Yoshizawa ,  Atsushi Kamada

    发明人： Itaru Arimoto ,  Kazuhiro Yoshizawa ,  Atsushi Kamada

    IPC分类号： A61K31/4704

    CPC分类号： C07D215/48

    摘要： A polymorph (A) of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide, having a diffraction peak at a diffraction angle (2θ±0.2°) of 15.75° in a powder X-ray diffraction; and a polymorph (B) of 4-[3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide, having a diffraction peak at a diffraction angle (2θ±0.2°) of 21.75° in a powder X-ray diffraction.

    摘要翻译： 在粉末X中具有衍射角（2θ±0.2°）为15.75°的衍射峰的4-（3-氯-4-（环丙基氨基羰基）氨基苯氧基）-7-甲氧基-6-喹啉甲酰胺的多晶型物（A） 射线衍射; 和具有衍射角（2θ±0.2°）为21.75°的衍射峰的4- [3-氯-4-（环丙基氨基羰基）氨基苯氧基] -7-甲氧基-6-喹啉甲酰胺的多晶型物（B） X射线衍射。

    Methods for producing isoindole derivatives
    3.
    发明授权
    Methods for producing isoindole derivatives 失效
    异吲哚衍生物的制备方法

    公开(公告)号：US07585982B2

    公开(公告)日：2009-09-08

    申请号：US11573814

    申请日：2005-07-27

    申请人： Kazuhiro Yoshizawa ,  Taiju Nakamura ,  Shigeto Negi

    发明人： Kazuhiro Yoshizawa ,  Taiju Nakamura ,  Shigeto Negi

    IPC分类号： C07D209/44

    CPC分类号： C07C255/59 ,  C07D209/44

    摘要： The present invention relates to a method for producing an isoindole derivative (compound (II)) with the following general formula (II): (wherein R1 and R2 each independently represents a C1-6 alkyl group) or a salt thereof, comprising the step of cyclizing, in a solvent, compound (I) with the following general formula (I): (wherein R1 and R2 have the same meanings as R1 and R2 in formula (II) above) or a salt thereof, or their hydrate or solvate in the presence of a base (Step 1).

    摘要翻译： 本发明涉及具有下列通式（II）的异吲哚衍生物（化合物（II））的制备方法：（其中R1和R2各自独立地表示C1-6烷基）或其盐，其包含步骤 在溶剂中使具有以下通式（I）的化合物（I）：其中R 1和R 2具有与上述式（II）中的R 1和R 2相同的含义）或其盐或其水合物或溶剂合物 在碱的存在下（步骤1）。

    Methods For Producing Isoindole Derivatives
    6.
    发明申请
    Methods For Producing Isoindole Derivatives 失效
    生产异吲哚衍生物的方法

    公开(公告)号：US20080214834A1

    公开(公告)日：2008-09-04

    申请号：US11573814

    申请日：2005-07-27

    申请人： Kazuhiro Yoshizawa ,  Taiju Nakamura ,  Shigeto Negi

    发明人： Kazuhiro Yoshizawa ,  Taiju Nakamura ,  Shigeto Negi

    IPC分类号： C07D209/44 ,  C07C255/59

    CPC分类号： C07C255/59 ,  C07D209/44

    摘要： The present invention relates to a method for producing an isoindole derivative (compound (II)) with the following general formula (II): (wherein R1 and R2 each independently represents a C1-6 alkyl group) or a salt thereof, comprising the step of cyclizing, in a solvent, compound (I) with the following general formula (I): (wherein R1 and R2 have the same meanings as R1 and R2 in formula (II) above) or a salt thereof, or their hydrate or solvate in the presence of a base (Step 1).

    摘要翻译： 本发明涉及以下通式（II）制备异吲哚衍生物（化合物（II））的方法：其中R 1和R 2各自独立地 代表C 1-6烷基）或其盐，包括在溶剂中使具有以下通式（I）的化合物（I）环化的步骤：（其中R“ 1和R 2具有与上述式（II）中的R 1和R 2相同的含义）或其盐 ，或其水合物或溶剂化物在碱的存在下（步骤1）。

    Control method and appartus for a radio telephone system
    7.
    发明授权
    Control method and appartus for a radio telephone system 失效
    无线电话系统的控制方法和附件

    公开(公告)号：US4897864A

    公开(公告)日：1990-01-30

    申请号：US178844

    申请日：1988-04-07

    申请人： Yoshitoshi Murata ,  Kazuhiro Yoshizawa ,  Akio Yotsutani ,  Koichi Ito

    发明人： Yoshitoshi Murata ,  Kazuhiro Yoshizawa ,  Akio Yotsutani ,  Koichi Ito

    IPC分类号： H04Q7/38 ,  H04B7/26 ,  H04M1/00 ,  H04M1/725 ,  H04M1/73 ,  H04M9/00 ,  H04Q7/20 ,  H04Q7/28

    CPC分类号： H04M9/00 ,  H04M1/72508

    摘要： A method and apparatus for controlling a radio telephone system wherein a speech channel is established between one radio telephone handset out of a plurality of radio telephone handsets and a base unit. An interphone switch for selecting intercom communication is provided for respective radio telephone handsets. The transmitters of the radio telephone handsets are turned OFF when the intercom switch is OFF, and transmitters of the radio telephone handsets are turned ON when the intercom switch is ON. Consequently the connection between a wired telephone channel and the plurality of radio telephone handsets can be controlled with a single base unit connected to the wired telephone channel.

    摘要翻译： 一种用于控制无线电话系统的方法和装置，其中在多个无线电话机中的一个无线电话手机与基本单元之间建立语音信道。 为各个无线电话机提供用于选择对讲通信的对讲机交换机。 当对讲机开关关闭时，无线电话机的发射机关闭，无线电话机的发射机在对讲机开关接通时变为ON。 因此，有线电话信道和多个无线电话机之间的连接可以用连接到有线电话信道的单个基本单元进行控制。

    UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME
    9.
    发明申请
    UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME 有权
    尿素衍生物及其制备方法

    公开(公告)号：US20090171112A1

    公开(公告)日：2009-07-02

    申请号：US12400562

    申请日：2009-03-09

    申请人： Toshihiko Naito ,  Kazuhiro Yoshizawa

    发明人： Toshihiko Naito ,  Kazuhiro Yoshizawa

    IPC分类号： C07C271/58 ,  C07C275/34

    CPC分类号： C07D215/233 ,  C07C275/34

    摘要： A process for preparing a compound (C) represented by the following formula: wherein R1 represents hydrogen, C1-6 alkyl or C3-8 cycloalkyl, and R2 represents hydrogen or methoxy, characterized by reacting a compound (A-1) represented by the following formula: wherein R1 has the same definition as above, with a compound (B) represented by the following formula: wherein R2 has the same definition as above, and L represents a leaving group, is provided. Compound (C) is effective for prevention or treatment of various diseases associated with angiogenesis neoplasia.

    摘要翻译： 一种制备由下式表示的化合物（C）的方法：其中R1表示氢，C1-6烷基或C3-8环烷基，R2表示氢或甲氧基，其特征在于使由 下式：其中R 1具有与上述相同的定义，与下式表示的化合物（B）：其中R2具有与上述相同的定义，L表示离去基团。 化合物（C）对于预防或治疗与血管生成瘤形成相关的各种疾病是有效的。

    Radio telephone system control method
    10.
    发明授权
    Radio telephone system control method 失效
    无线电话系统控制方法

    公开(公告)号：US5140628A

    公开(公告)日：1992-08-18

    申请号：US443334

    申请日：1989-11-30

    申请人： Yoshitoshi Murata ,  Kazuhiro Yoshizawa ,  Akio Yotsutani ,  Koichi Ito

    发明人： Yoshitoshi Murata ,  Kazuhiro Yoshizawa ,  Akio Yotsutani ,  Koichi Ito

    IPC分类号： H04M1/725 ,  H04M9/00

    CPC分类号： H04M1/72508 ,  H04M9/00

    摘要： In a method and apparatus for controlling a radio telephone system, a speech channel is established between the slave radio set of a plurality of radio telephone sets and a radio set of a base unit. An intercom switch for selecting intercom performances is provided for respective radio telephone sets. The slave radio sets of the radio telephone sets are turned OFF when the intercom switch is OFF, and transmitters of the slave radio sets of the radio telephone sets are turned ON. Consequently the connection between a wired telephone channel and the plurality of radio telephone sets can be controlled with a single base unit connected to the wired telephone channel.

    摘要翻译： 在用于控制无线电话系统的方法和装置中，在多个无线电话机的从无线电设备和基站单元的无线电设备之间建立语音信道。 为各个无线电话机提供用于选择对讲性能的内部通信交换机。 无线电话机的从属无线电设备在内部通信开关关闭时关闭，无线电话机的从无线电设备的发射机接通。 因此，有线电话信道与多个无线电话机之间的连接可以用连接到有线电话信道的单个基本单元进行控制。