-
公开(公告)号：US20130210797A1
公开(公告)日：2013-08-15
申请号：US13819790
申请日：2011-08-29
申请人： Jürgen Klar , Georges Von Degenfeld , Hans-Georg Lerchen , Barbara Albrecht-Küpper , Andreas Knorr , Peter Sandner , Daniel Meiibom
发明人： Jürgen Klar , Georges Von Degenfeld , Hans-Georg Lerchen , Barbara Albrecht-Küpper , Andreas Knorr , Peter Sandner , Daniel Meiibom
IPC分类号： C07D417/12 , A61K45/06 , C07D417/14 , A61K31/4439 , C07D413/12
CPC分类号： A61K31/4439 , A61K9/0048 , A61K9/08 , A61K38/05 , A61K45/06 , C07D413/12 , C07D417/12 , C07D417/14
摘要： The present invention relates to the use of selective adenosine A1 agonists, in particular the dicyanopyridines of formula (I), for the treatment and/or prophylaxis of glaucoma and ocular hypertension as well as the their use for the production of a medicament for the treatment and/or prophylaxis of glaucoma and ocular hypertension.
-
2.发明申请公开(公告)号：US20120058983A1
公开(公告)日：2012-03-08
申请号：US13210889
申请日：2011-08-16
申请人： Jürgen Klar , Georges VON DEGENFELD , Hans-Georg LERCHEN , Barbara Albrecht-Küpper , Andreas KNORR , Peter SANDNER , Daniel MEIBOM
发明人： Jürgen Klar , Georges VON DEGENFELD , Hans-Georg LERCHEN , Barbara Albrecht-Küpper , Andreas KNORR , Peter SANDNER , Daniel MEIBOM
IPC分类号： A61K31/4439 , A61P27/06 , A61P27/02 , C07D417/12
CPC分类号： A61K31/4439 , A61K9/0048 , A61K9/08 , A61K38/05 , A61K45/06 , C07D413/12 , C07D417/12 , C07D417/14
摘要： The present invention relates to the use of selective adenosine A1 agonists, in particular the dicyanopyridines of formula (I), for the treatment and/or prophylaxis of glaucoma and ocular hypertension as well as the their use for the production of a medicament for the treatment and/or prophylaxis of glaucoma and ocular hypertension.
摘要翻译： 本发明涉及选择性腺苷A1激动剂，特别是式（I）的二氰基吡啶用于治疗和/或预防青光眼和高眼压症及其用于生产治疗药物的用途的用途 和/或预防青光眼和高眼压症。
-
3.发明授权公开(公告)号：US09040566B2
公开(公告)日：2015-05-26
申请号：US13819790
申请日：2011-08-29
申请人： Jürgen Klar , Georges Von Degenfeld , Hans-Georg Lerchen , Barbara Albrecht-Küpper , Andreas Knorr , Peter Sandner , Daniel Meibom
发明人： Jürgen Klar , Georges Von Degenfeld , Hans-Georg Lerchen , Barbara Albrecht-Küpper , Andreas Knorr , Peter Sandner , Daniel Meibom
IPC分类号： A01N43/40 , A61K31/44 , C07D409/00 , C07D411/00 , C07D405/00 , C07D417/12 , A61K9/00 , A61K9/08 , A61K31/4439 , A61K45/06 , C07D413/12 , C07D417/14
CPC分类号： A61K31/4439 , A61K9/0048 , A61K9/08 , A61K38/05 , A61K45/06 , C07D413/12 , C07D417/12 , C07D417/14
摘要： The present invention relates to the use of selective adenosine A1 agonists, in particular the dicyanopyridines of formula (I), for the treatment and/or prophylaxis of glaucoma and ocular hypertension as well as the their use for the production of a medicament for the treatment and/or prophylaxis of glaucoma and ocular hypertension.
摘要翻译： 本发明涉及选择性腺苷A1激动剂，特别是式（I）的二氰基吡啶用于治疗和/或预防青光眼和高眼压症及其用于生产治疗药物的用途的用途 和/或预防青光眼和高眼压症。
-
公开(公告)号：US09040691B2
公开(公告)日：2015-05-26
申请号：US14130586
申请日：2012-06-26
申请人： Jürgen Klar , Verena Vöhringer , Joachim Telser , Mario Lobell , Frank Süβmeier , Volkhart Min-Jian Li , Michael Böttger , Stefan Golz , Dieter Lang , Karl-Heinz Schlemmer , Thomas Schlange , Andreas Schall , Wenlang Fu
发明人： Jürgen Klar , Verena Vöhringer , Joachim Telser , Mario Lobell , Frank Süβmeier , Volkhart Min-Jian Li , Michael Böttger , Stefan Golz , Dieter Lang , Karl-Heinz Schlemmer , Thomas Schlange , Andreas Schall , Wenlang Fu
IPC分类号： C07D487/04 , C07D401/04 , A61K31/53 , A61K31/4427 , A61P25/02 , A61P27/02 , A61K31/5377
CPC分类号： A61K31/5377 , A61K31/4427 , A61K31/53 , C07D401/04 , C07D487/04
摘要： This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.
摘要翻译： 本发明涉及式（I）的新的5 - [（羟甲基）芳基] - 取代的吡咯并[2,1-f] [1,2,4]三嗪-4-胺，用于制备这些化合物， 含有这些化合物的药物组合物，以及这些化合物或组合物用于治疗血管生成相关病症，特别是血管发生相关性眼部疾病的用途。
-
公开(公告)号：US20140256718A1
公开(公告)日：2014-09-11
申请号：US14130586
申请日：2012-06-26
申请人： Jürgen Klar , Verena Vöhringer , Joachim Telser , Mario Lobell , Frank Süssmeier , Volkhart Min-Jian Li , Michael Böttger , Stefan Golz , Dieter Lang , Karl-Heinz Schlemmer , Thomas Schlange , Andreas Schall , Wenlang Fu
发明人： Jürgen Klar , Verena Vöhringer , Joachim Telser , Mario Lobell , Frank Süssmeier , Volkhart Min-Jian Li , Michael Böttger , Stefan Golz , Dieter Lang , Karl-Heinz Schlemmer , Thomas Schlange , Andreas Schall , Wenlang Fu
IPC分类号： A61K31/5377 , C07D487/04 , A61K31/53
CPC分类号： A61K31/5377 , A61K31/4427 , A61K31/53 , C07D401/04 , C07D487/04
摘要： This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.
摘要翻译： 本发明涉及式（I）的新的5 - [（羟甲基）芳基] - 取代的吡咯并[2,1-f] [1,2,4]三嗪-4-胺，用于制备这些化合物， 含有这些化合物的药物组合物，以及这些化合物或组合物用于治疗血管生成相关病症，特别是血管发生相关性眼部疾病的用途。
-
6.发明申请公开(公告)号：US20140235678A1
公开(公告)日：2014-08-21
申请号：US14129557
申请日：2012-06-26
申请人： Michael Böttger , Julia Freundlieb , Claudia Hirth-Dietrich , Jürgen Klar , Uwe Muenster , Andreas Ohm , Bernd Riedl
发明人： Michael Böttger , Julia Freundlieb , Claudia Hirth-Dietrich , Jürgen Klar , Uwe Muenster , Andreas Ohm , Bernd Riedl
IPC分类号： A61K9/00 , A61K31/255 , A61K31/44
CPC分类号： A61K9/0048 , A61K31/255 , A61K31/44 , A61K47/06 , A61K47/14 , A61K47/26 , A61K47/38
摘要： The present invention relates to topical ophthalmological pharmaceutical compositions containing sorafenib or a pharmaceutically acceptable salt thereof or a polymorph, hydrate or solvate thereof and its process of preparation and its use for treating ophthalmological disorders.
摘要翻译： 本发明涉及含有索拉非尼或其药学上可接受的盐或其多晶型物，水合物或溶剂合物及其制备方法及其用于治疗眼科疾病的用途的局部眼科药物组合物。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.031 秒)
