公开(公告)号：US10188671B2

公开(公告)日：2019-01-29

申请号：US15555721

申请日：2016-03-04

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Motomu Kanai ,  Yohei Soma ,  Yusuke Shimizu ,  Atsuhiko Taniguchi ,  Kounosuke Oisaki ,  Yoichiro Kuninobu

IPC: A61K31/69 ,  C07F5/02 ,  A61P25/28 ,  A61P3/10 ,  A61P25/16 ,  C07D401/14 ,  C07D455/04 ,  C07D207/44 ,  C07D207/456 ,  A61K31/4025 ,  A61K31/4725 ,  C07D207/46 ,  C07D215/06 ,  A61K41/00

Abstract: Provided is a compound which is useful as an in vivo applicable, amyloid-oxygenating catalyst selective for amyloid and applicable not only to an Aβ peptide, but also to other amyloids and a drug containing the compound for preventing and/or treating amyloid-related diseases. Disclosed is a boron-dipyrrin complex represented by the following formula (1)