METHOD FOR CONTROLLING PROLIFERATION OF CORD BLOOD HEMATOPOIETIC STEM CELLS AND USE THEREOF
    1.
    发明申请
    METHOD FOR CONTROLLING PROLIFERATION OF CORD BLOOD HEMATOPOIETIC STEM CELLS AND USE THEREOF 审中-公开
    用于控制牙髓血细胞增生干细胞增殖的方法及其用途

    公开(公告)号:US20130143322A1

    公开(公告)日:2013-06-06

    申请号:US13754336

    申请日:2013-01-30

    申请人: JMS CO., LTD.

    IPC分类号: C12N5/0789

    摘要: The present invention provides a method for controlling the proliferation and differentiation of cord blood-derived hematopoietic stem cells with excellent safety when proliferating them by culturing. The hematopoietic stem cells are inoculated into a medium containing a sonicated liquid component of cord blood. The proliferation and differentiation of the cord blood hematopoietic stem cells can be inhibited in the presence of the sonicated liquid component of cord blood. On the contrary, the proliferation of cord blood hematopoietic stem cells can be accelerated by inoculating the hematopoietic stem cells into a medium containing a non-sonicated liquid component of cord blood. Thus, according to the present invention, by using serum derived from cord blood, it is possible to regulate the inhibition of the proliferation and differentiation of cord blood hematopoietic stem cells and the acceleration of the proliferation of the same as desired.

    摘要翻译: 本发明提供了一种通过培养来增强脐带血衍生的造血干细胞增殖和分化的方法,其具有极好的安全性。 将造血干细胞接种到含有超声处理的脐带血液成分的培养基中。 脐带血造血干细胞的增殖和分化可以在脐带血的超声液化成分的存在下被抑制。 相反,脐带血造血干细胞的增殖可以通过将造血干细胞接种到含有非超声处理的脐带血液成分的培养基中来加速。 因此,根据本发明,通过使用来自脐带血的血清,可以调节对脐血造血干细胞的增殖和分化的抑制以及根据需要加速其增殖。

    BLOOD COMPONENT SEPARATION DEVICE
    2.
    发明申请
    BLOOD COMPONENT SEPARATION DEVICE 审中-公开
    血液成分分离装置

    公开(公告)号:US20160235906A1

    公开(公告)日:2016-08-18

    申请号:US15024570

    申请日:2014-08-21

    IPC分类号: A61M1/36 A61J1/22

    摘要: A blood reservoir (20) for storing blood includes a first storage section (21), a second storage section (22), and a third storage section (23) that is provided between the first storage section and the second storage section, and communicates with the first storage section and the second storage section. A volume of the blood reservoir (20) can be adjusted by changing the amount of expansion or contraction of a bellows structure (28) using a bellows adjustment mechanism (83, 93).

    摘要翻译: 用于存储血液的血液储存器(20)包括设置在第一存储部分和第二存储部分之间的第一存储部分(21),第二存储部分(22)和第三存储部分(23),并且连通 与第一存储部分和第二存储部分。 可以通过使用波纹管调节机构(83,93)改变波纹管结构(28)的膨胀或收缩量来调节血液容积(20)的体积。