-
公开(公告)号：US20180263902A1
公开(公告)日：2018-09-20
申请号：US15463609
申请日：2017-03-20
IPC分类号： A61K9/00 , A61K9/20 , A61K31/167
CPC分类号： A61K9/0056 , A61K9/2081 , A61K9/2095 , A61K9/5036 , A61K31/167
摘要： In one aspect the present invention features a process for making a tablet comprising the step of applying radiofrequency energy to a powder blend comprising lossy coated particles and at least one pharmaceutically active agent to sinter said powder blend into a tablet, said lossy coated particles comprising a substrate having a Q value of greater than 100 that is at least partially coated with a lossy coating comprising Hydrogenated Starch Hydrolysate.
-
公开(公告)号：US20170354606A1
公开(公告)日：2017-12-14
申请号：US15689076
申请日：2017-08-29
发明人： Christopher E. Szymczak , Vipul Dave , Gerard P. McNally , David B. Cochran , Gregory Koll , Stephen Ulrich
IPC分类号： A61K9/20 , B01J2/00 , A61K9/50 , A61K31/137 , B01J2/18 , A61K31/138 , A61K31/167
CPC分类号： A61K9/2095 , A61K9/2081 , A61K9/50 , A61K31/137 , A61K31/138 , A61K31/167 , B01J2/006 , B01J2/18
摘要： In one aspect the present invention features process for making a tablet comprising at least one pharmaceutically active agent, said method comprising the step of applying radiofrequency energy to a powder blend to sinter said powder blend into said tablet, wherein said powder blend comprises lossy coated particles and said at least one pharmaceutically active agent, wherein said lossy coated particles comprises a substrate that is at least partially coated with a lossy coating comprising at least one activator, wherein said substrate has a Q value of greater than 100 and said activator has a Q value of less than 75.
-
公开(公告)号：US09511028B2
公开(公告)日：2016-12-06
申请号：US13803527
申请日：2013-03-14
IPC分类号： A61K9/00 , A61K9/20 , A61K31/167 , A61K31/426 , A61K31/7004
CPC分类号： A61K9/2081 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K31/167 , A61K31/426 , A61K31/7004 , A61K2300/00
摘要： The present invention features a tablet containing at least one first material, at least one second material, and at least one pharmaceutically active agent, wherein: (a) the first material is a dielectric water-containing material (i) containing from about 1 to about 5 percent, by weight, of bound water and (ii) having a dielectric loss, when measured at a density of between 0.15 and 0.5 g/cc, of from about 0.05 to about 0.7; and (b) the second material (i) having a water solubility from about 20 to about 400 g per 100 g of water at 25° C., (ii) having a dielectric loss, when measured at a density between 0.5 and 1 g/cc, of less than about 0.05.
-
公开(公告)号：US20170035656A1
公开(公告)日：2017-02-09
申请号：US15296368
申请日：2016-10-18
发明人： Joseph R. Luber , Frank J. Bunick , Harry S. Sowden , Leo B. Kriksunov , Christopher E. Szymczak
IPC分类号： A61J3/10 , A61K9/20 , B29C43/14 , A61K31/138 , A61K31/167 , A61K9/00 , A61K31/4545
CPC分类号： A61J3/10 , A61K9/0056 , A61K9/145 , A61K9/146 , A61K9/2018 , A61K9/2031 , A61K9/2036 , A61K9/205 , A61K9/2086 , A61K9/2095 , A61K31/138 , A61K31/167 , A61K31/4545 , B29C43/006 , B29C43/146 , B29C2043/3628 , B30B11/027 , B30B11/085 , B30B11/10 , B30B15/34
摘要： The present invention features a tablet containing a first layer and a second layer, wherein: (i) the first layer includes a pharmaceutically active agent and the composition of the first layer is different from the composition of the second layer; (ii) the tablet has a density less than about 0.8 g/cc; and (iii) the tablet disintegrates in the mouth when placed on the tongue in less than about 30 seconds.
摘要翻译： 本发明的特征在于含有第一层和第二层的片剂，其中：（i）第一层包含药物活性剂，第一层的组合物不同于第二层的组成; （ii）片剂的密度小于约0.8g / cc; 和（iii）片剂在短时间内放置在舌头上时在口中崩解。
-
公开(公告)号：US09789066B2
公开(公告)日：2017-10-17
申请号：US14592176
申请日：2015-01-08
发明人： Christopher E. Szymczak , Vipul Dave , Gerard P. McNally , David B. Cochran , Gregory Koll , Stephen Ulrich
IPC分类号： B01J2/00 , B01J2/18 , A61K9/20 , A61K31/137 , A61K31/138 , A61K31/167 , A61K9/50
CPC分类号： A61K9/2095 , A61K9/2081 , A61K9/50 , A61K31/137 , A61K31/138 , A61K31/167 , B01J2/006 , B01J2/18
摘要： In one aspect the present invention features process for making a tablet comprising at least one pharmaceutically active agent, said method comprising the step of applying radiofrequency energy to a powder blend to sinter said powder blend into said tablet, wherein said powder blend comprises lossy coated particles and said at least one pharmaceutically active agent, wherein said lossy coated particles comprises a substrate that is at least partially coated with a lossy coating comprising at least one activator, wherein said substrate has a Q value of greater than 100 and said activator has a Q value of less than 75.
-
-
-
-
搜索结果
5 条记录 (耗时 0.018 秒)
