专利检索 ap:("Jack A. Elias" OR "Chirag R. Parikh" OR "Lloyd G. Cantley") AND inv:"Lloyd G. Cantley" 第 1 页

1.

发明申请
Chitinase-3-Like Protein 1 as a Biomarker of Recovery from Kidney Injury 审中-公开
标题翻译：几丁质酶-3样蛋白1作为从肾损伤中恢复的生物标志物

公开(公告)号：US20130035290A1

公开(公告)日：2013-02-07

申请号：US13474011

申请日：2012-05-17

申请人： Jack A. Elias , Chirag R. Parikh , Lloyd G. Cantley

发明人： Jack A. Elias , Chirag R. Parikh , Lloyd G. Cantley

IPC分类号： G01N33/566 , A61P13/12 , A61K38/17 , C12Q1/68 , C40B30/04

CPC分类号： A61K38/47 , C12Q1/6883 , C12Q2600/158 , G01N33/6887 , G01N33/6893 , G01N2333/924 , G01N2800/347 , G01N2800/52 , G01N2800/54 , G01N2800/56

摘要： The present invention provides compositions and methods for the detection, treatment, and prevention of a kidney injury. The invention relates to the discovery that chitinase 3-like 1/Brp-39/YKL-40 serves as both a biomarker for the degree of kidney injury and a critical mediator of a reparative response in the kidney.

摘要翻译： 本发明提供了用于检测，治疗和预防肾损伤的组合物和方法。本发明涉及几丁质酶3样1 / Brp-39 / YKL-40用作肾损伤程度的生物标志物和肾脏修复反应的关键介质的发现。