公开(公告)号：US4132599A

公开(公告)日：1979-01-02

申请号：US680015

申请日：1976-04-23

申请人： James C. Administrator of the National Aeronautics and Space Administration, with respect to an invention of Fletcher ,  Grace L. Picciolo ,  Emmett W. Chappelle ,  Jody W. Deming ,  Christian G. Shrock ,  Hillar Vellend ,  Michael J. Barza ,  Louis Weinstein

发明人： James C. Administrator of the National Aeronautics and Space Administration, with respect to an invention of Fletcher ,  Grace L. Picciolo ,  Emmett W. Chappelle ,  Jody W. Deming ,  Christian G. Shrock ,  Hillar Vellend ,  Michael J. Barza ,  Louis Weinstein

IPC分类号： C12Q1/18 ,  C12K1/00

CPC分类号： C12Q1/18

摘要： Method for the quick determination of the susceptibilities of various unidentified bacteria contained in an aqueous physiological fluid sample, particularly urine, to one or more antibiotics. A bacterial adenosine triphosphate (ATP) assay is carried out after the elimination of non-bacterial ATP to determine whether an infection exists. If an infection does exist, a portion of the sample is further processed, including subjecting parts of the portion to one or more antibiotics. Growth of the bacteria in the parts are determined, again by an ATP assay, to determine whether the unidentified bacteria in the sample are susceptible to the antibiotic or antibiotics under test.

摘要翻译： 用于快速测定包含在水性生理液体样品，特别是尿液中的各种不明细菌对一种或多种抗生素的敏感性的方法。 在消除非细菌ATP后进行细菌三磷酸腺苷（ATP）测定以确定是否存在感染。 如果感染确实存在，则进一步处理样品的一部分，包括将该部分的部分经受一种或多种抗生素。 通过ATP测定法再次测定部分中细菌的生长，以确定样品中未鉴定的细菌是否对被测抗生素或抗生素敏感。