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公开(公告)号:US08912229B2
公开(公告)日:2014-12-16
申请号:US14110423
申请日:2012-04-06
IPC分类号: A61K31/35 , A61K31/335 , C07D309/00 , C07D407/00 , A61K31/357 , C07D493/06 , C07D493/04 , A61K45/06
CPC分类号: C07D493/06 , A61K31/357 , A61K45/06 , C07D493/04
摘要: The present application discloses new taxane analogs, intermediates and methods for producing them. The present application is also directed to pharmaceutical formulations comprising abeo-taxanes and methods of treating cancer with the abeo-taxanes.
摘要翻译: 本申请公开了新的紫杉烷类似物,中间体及其生产方法。 本申请还涉及包含抗紫杉烷类的药物制剂和用抗紫杉烷类药物治疗癌症的方法。
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公开(公告)号:US20140093503A1
公开(公告)日:2014-04-03
申请号:US14110423
申请日:2012-04-06
IPC分类号: C07D493/06 , A61K45/06 , A61K31/357
CPC分类号: C07D493/06 , A61K31/357 , A61K45/06 , C07D493/04
摘要: The present application discloses new taxane analogs, intermediates and methods for producing them. The present application is also directed to pharmaceutical formulations comprising abeo-taxanes and methods of treating cancer with the abeo-taxanes.
摘要翻译: 本申请公开了新的紫杉烷类似物,中间体及其生产方法。 本申请还涉及包含抗紫杉烷类的药物制剂和用抗紫杉烷类药物治疗癌症的方法。
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公开(公告)号:US4362435A
公开(公告)日:1982-12-07
申请号:US56456
申请日:1979-07-10
申请人: John T. Henry
发明人: John T. Henry
CPC分类号: F16L1/036
摘要: Apparatus lays pipe in a trench and joins successive sections thereof. An elongated carriage is of a length sufficient to straddle the trench and includes propelling means for engaging the surface outward from the respective upper sides of the trench and moving the carriage therealong. The propelling means is steerably driven. A crane arises from the carriage and includes an adjustably articulated arm of adjustable length and which has an outer end portion controllably movable both laterally with respect to the trench and between respective positions above and within the trench. The crane is mounted upon the carriage so as to permit tilting relative thereto and, thus, relative to the sidewalls of the trench. A controllable grapple is mounted on the outer end of the arm and is controlled to engage and disengage the pipe.
摘要翻译: 设备将管道放置在沟槽中并连接其连续的部分。 细长的滑架具有足以跨越沟槽的长度,并且包括推进装置,用于从沟槽的相应上侧向外接合表面并沿其移动托架。 推进手段是可驾驶的。 起重机由滑架产生,并且包括可调节长度的可调节铰接臂,并且具有可相对于沟槽在横向上以及在沟槽内上方和内部的相应位置之间可控地移动的外端部分。 起重机安装在滑架上,以便允许相对于其移动并因此相对于沟槽的侧壁倾斜。 可控抓斗安装在臂的外端,并被控制以使管接合和脱开。
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公开(公告)号:US4682912A
公开(公告)日:1987-07-28
申请号:US214500
申请日:1980-12-09
申请人: John T. Henry
发明人: John T. Henry
CPC分类号: F16L1/036 , B66C1/30 , B66C23/44 , Y10S29/046 , Y10T29/49945
摘要: For laying and joining successive sections of pipe, a vehicle is movable over a course along which the pipe is to be laid. Carried on the vehicle is a crane, the outer end portion of which is movable both vertically and horizontally relative to the course of the pipeline. A controllable grapple mounted on that outer end of the crane is engageable with a section of the pipe, so that operation of the grapple together with the crane enables each section of the pipe to be picked up, moved into position over and deposited along the course. A vibrator is attached to the grapple and serves to induce vibration thereinto and from the grapple into the section of pipe being carried. The vibration is induced as an end of the section carried by the grapple is slidably mated with another section of the pipe which lies along the course. The vibration also is used to assist in bedding the pipe section being laid.
摘要翻译: 为了铺设和连接管道的连续部分,车辆可以在要铺设管道的道路上移动。 在车辆上携带的是起重机,其外端部相对于管道的过程垂直和水平地移动。 安装在起重机的外端上的可控抓斗可与管道的一部分接合,使得抓斗与起重机一起的操作使得管道的每个部分能够被拾起,移动到位置并沿着该路线沉积 。 振动器附接到抓钩并用于引起振动,并且从抓斗进入被承载的管的部分。 当抓斗所承载的部分的一端与沿着管道的另一部分滑动配合时,引起振动。 振动也用于帮助铺设的管段。
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公开(公告)号:US4325432A
公开(公告)日:1982-04-20
申请号:US138098
申请日:1980-04-07
申请人: John T. Henry
发明人: John T. Henry
CPC分类号: B01J19/14 , E21B43/168 , E21B43/18 , E21B43/24 , E21B43/30
摘要: This invention relates to a method of recovering petroleum from a subterranean petroleum-containing formation comprising the steps of providing an injection well containing a flow path in fluid communication with at least a portion of the petroleum-containing formation, providing at least one production well in fluid communication with at least a portion of the petroleum-containing formation, providing heated and pressurized combustion byproducts, rendering the combustion byproducts relatively inert by contacting same with manganese and/or manganese dioxide, heating the combustion byproducts to a predetermined temperature, and injecting the heated combustion byproducts into the injection well for heating the petroleum in the petroleum-containing formation to render it less viscous and for pressurizing the petroleum to help force it to the production well for receiving it from the petroleum-containing formation.
摘要翻译: 本发明涉及一种从地下含石油地层中回收石油的方法,包括以下步骤:提供含有与含石油地层的至少一部分流体连通的流动路径的注入井,提供至少一个生产井 与含石油的地层的至少一部分流体连通,提供加热和加压的燃烧副产物,通过使其与锰和/或二氧化锰接触使燃烧副产物相对惰性,将燃烧副产物加热至预定温度,并将 加热的燃烧副产物进入注入井,用于加热含石油地层中的石油,使其粘度较小,并对石油进行加压,以帮助其强制生产,以便从含石油的地层接收石油。
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