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    Epoxy resin for fiber reinforced composite materials
    1.
    发明授权
    Epoxy resin for fiber reinforced composite materials 有权
    纤维增强复合材料用环氧树脂

    公开(公告)号：US07208228B2

    公开(公告)日：2007-04-24

    申请号：US10420776

    申请日：2003-04-23

    申请人： James E. Brown ,  Norimitsu Natsume ,  Nobuyuki Odagiri ,  Jeffrey J. Hawkey ,  Brian S. Hayes

    发明人： James E. Brown ,  Norimitsu Natsume ,  Nobuyuki Odagiri ,  Jeffrey J. Hawkey ,  Brian S. Hayes

    IPC分类号： B32B27/38 ,  B32B27/04 ,  B32B27/18 ,  C08L63/00

    CPC分类号： C08J5/24 ,  C08J2363/00 ,  C08L63/00 ,  Y10T428/24994 ,  Y10T428/31511 ,  Y10T428/31525 ,  C08L2666/04

    摘要： An epoxy resin composition for a cured material, comprising (A) an epoxy resin comprising an epoxy compound X, the epoxy compound X has an epoxy equivalent weight of at least 400, (B) a curing agent, and (C) a liquid rubber that is liquid at room temperature and comprises a reactive group; wherein the epoxy compound X has a solubility parameter value of SpX, the liquid rubber has a solubility parameter value of SpY and the ratio of SpY/SpX could be in the range of 0.7 to 1.3; and wherein the liquid rubber could form no visible domains by optical microscopy or has a maximum domain size of at most 3 microns in the cured material is described. The epoxy resin composition provides a fiber-reinforced material with higher compressive modulus and strength, toughness and better handling ability over standard epoxy resin systems. This invention is excellent for small thin walled tube structures like fishing rods or applications that require good compressive strength.

    摘要翻译： 一种用于固化材料的环氧树脂组合物，其包含（A）环氧树脂，其包含环氧化合物X，环氧化合物X的环氧当量为至少400，（B）固化剂，和（C）液体橡胶 在室温下为液体，包含反应性基团; 其中环氧化合物X具有SpX的溶解度参数值，液体橡胶具有SpY的溶解度参数值，SpY / SpX的比例可以在0.7至1.3的范围内; 并且其中液体橡胶可以通过光学显微镜不形成可见结构域，或者在固化材料中具有至多3微米的最大结构域尺寸。 环氧树脂组合物提供了比标准环氧树脂体系更高的压缩模量和强度，韧性和更好的处理能力的纤维增强材料。 本发明对于诸如钓鱼杆或需要良好抗压强度的应用的小型薄壁管结构来说是非常好的。

    ICE THERAPY METHOD AND APPARATUS
    2.
    发明申请
    ICE THERAPY METHOD AND APPARATUS 审中-公开

    公开(公告)号：US20190388268A1

    公开(公告)日：2019-12-26

    申请号：US16018850

    申请日：2018-06-26

    申请人： James E. Brown

    发明人： James E. Brown

    IPC分类号： A61F7/02 ,  A61F7/00 ,  A61F7/10

    摘要： A method of using an ice therapy machine involves replacing water with windshield washer fluid containing ethanol or ethylene glycol, and placing the main unit of the ice therapy machine, including the ice chest and pump, in a freezer to prevent the ice in the ice chest from melting. The freezer has been modified to include openings for passage of the fluid-circulating tubes of the ice therapy machine, and an opening for the power cord of the ice therapy machine, which supplies power to the pump. Alternatively, the door of the freezer may be replaced by an insulated panel having openings for the coolant circulating tubes and power cord. An on/off switch may be installed in the power cord so that the pump can be turned on and off without having to open the freezer door.

    Controlled release compositions
    6.
    发明申请
    Controlled release compositions 审中-公开
    控制释放组合物

    公开(公告)号：US20080176785A1

    公开(公告)日：2008-07-24

    申请号：US11888664

    申请日：2007-07-31

    申请人： James E. Brown ,  John W. Gibson

    发明人： James E. Brown ,  John W. Gibson

    IPC分类号： A61K47/30 ,  A61K38/22

    CPC分类号： A61K38/09 ,  A61K9/0024

    摘要： Controlled release compositions for controlling release of a GnRH molecule or a GnRH analog are provided. The compositions include a GnRH molecule or GnRH analog as an active agent, and a controlled release component for controlling release of the GnRH molecule or GnRH analog from the composition. The compositions provide a sustained mean steady state plasma concentration (Css) of the active agent of at least about 1.5 ng/mL for a period of at least about 48 hours when the composition is administered to a subject. In addition, the use of a controlled release component in the manufacture of a composition for the controlled release of a GnRH molecule or GnRH analog is provided. The controlled release component is capable of providing a sustained mean steady state plasma concentration (Css) of the active agent of at least about 1.5 ng/mL for a period of at least about 48 hours when the manufactured composition is administered to a subject. The controlled release component can include a polymeric material and/or a non-polymeric material. When the compositions are administered to a subject, for example when implanted, the compositions release the active agent in a controlled fashion. Methods for producing the compositions are also provided, as are methods of using the compositions to provide for controlled release of the GnRH molecule or GnRH analog in a subject.

    摘要翻译： 提供了用于控制GnRH分子或GnRH类似物释放的控制释放组合物。 组合物包括GnRH分子或GnRH类似物作为活性剂，以及用于控制组合物中GnRH分子或GnRH类似物释放的控释组分。 当将组合物施用于受试者时，组合物提供至少约1.5ng / mL的持续的平均稳态血浆浓度至少约48小时的持续平均稳态血浆浓度（C ss） 。 此外，提供了控制释放组分在制备用于控制释放GnRH分子或GnRH类似物的组合物中的用途。 控制释放组分能够在至少约48ng / mL的时间内提供至少约1.5ng / mL活性剂的持续平均稳态血浆浓度（C ss） 将组合物施用于受试者。 控制释放组分可以包括聚合物材料和/或非聚合材料。 当将组合物施用于受试者时，例如当植入时，组合物以受控的方式释放活性剂。 还提供了用于制备组合物的方法，以及使用该组合物提供受试者中GnRH分子或GnRH类似物的受控释放的方法。