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公开(公告)号:US20070036742A1
公开(公告)日:2007-02-15
申请号:US11500704
申请日:2006-08-08
申请人: James Roufs , Lane Duvel , David Fast , Kelly Glynn
发明人: James Roufs , Lane Duvel , David Fast , Kelly Glynn
IPC分类号: A61K8/97 , A61K38/43 , A61K36/889 , A61K36/82 , A61K36/31 , A61K36/537 , A61K36/48 , A61K36/73 , A61K36/28
CPC分类号: A61K8/96 , A61K8/342 , A61K8/355 , A61K8/4973 , A61K8/498 , A61K8/678 , A61K8/97 , A61K8/9706 , A61K36/03 , A61K36/31 , A61K36/324 , A61K36/48 , A61K36/537 , A61K36/73 , A61K36/82 , A61K36/889 , A61Q7/00 , A61K2300/00
摘要: The present invention relates to compositions and methods for modulating hair growth or regrowth. The compositions of the present invention comprise extracts of one or more of the following: Boswellia serrata, Undaria pinnatifida, green tea (e.g., Camellia sinensis), shiso, Pureraria mirifica, luteolin (e.g. Perilla ocymoides leaf extract), astilbin, vitamin E, amentoflavone, tetrahydropiperine, licochalcone, astaxanthin, red clover, Brassica juncea, unfermented green rooibos, enzyme CoQ10, salvia, ximenynic acid, hops oleoresin, apple, soy, saw palmetto, or ellagic extract, or any derivative thereof. In particular, the compositions and methods of the present invention can be used to stimulate or increase hair growth and/or prevent or slow the loss of hair by having one or more of the following functions: (a) inhibiting synthesis of DHT; (b) inhibiting proteasomal activity; (c) inhibiting IL-1 activity; (d) increasing vascularization; (e) increasing expression of vascular endothelial growth factor; (f) increasing expression of keratinocyte growth factor; (g) inhibiting inflammation; or (h) acting as an antibacterial.
摘要翻译: 本发明涉及用于调节毛发生长或再生长的组合物和方法。 本发明的组合物包括以下中的一种或多种的提取物:浆果乳杆菌(Boswellia serrata),无花果(Undaria pinnatifida),绿茶(例如,山茶花),紫苏,纯天竺葵,木犀草素(例如紫苏叶提取物),青霉素,维生素E, 黄曲霉酮,四氢哌啶,丽科查酮,虾青素,红三叶草,芥菜,未发酵绿色果酱,酶CoQ10,丹参,西门子酸,啤酒花油树脂,苹果,大豆,锯棕榈或鞣花提取物或其任何衍生物。 特别地,本发明的组合物和方法可用于刺激或增加毛发生长和/或通过具有以下一个或多个功能来防止或减缓头发的损失:(a)抑制DHT的合成; (b)抑制蛋白酶体活性; (c)抑制IL-1活性; (d)增加血管化; (e)增加血管内皮生长因子的表达; (f)增加角化细胞生长因子的表达; (g)抑制炎症; 或(h)作为抗菌剂。