-
公开(公告)号：US06299930B1
公开(公告)日：2001-10-09
申请号：US09400657
申请日：1999-09-20
IPC分类号： B05D300
CPC分类号： A61M39/0247 , A61B17/00491 , A61F2310/00796 , A61F2310/00928 , A61L29/106 , A61L31/088 , A61M2039/0261
摘要： Percutaneous implants are disclosed including a portion implantable into a patient, a dermal bonding region capable of forming a bond between the implant and a dermal layer of the patient after the implantable portion is implanted into the patient, and the dermal bonding region including a substrate with a discontinuous coating of particulate bioactive glass wherein the average spacing between the particles of bioactive glass is predetermined and at least about 20 microns prior to implantation into the patient. Also disclosed are bioactive coatings including a substrate and fibers and/or particles of bioactive glass distributed on the substrate with a predetermined average interfiber distance of at least about 20 microns.
摘要翻译： 公开了经皮植入物，其包括可植入患者体内的部分，在将可植入部分植入患者体内后能够在植入物和患者真皮层之间形成结合的真皮粘合区域，并且真皮粘合区域包括具有 颗粒生物活性玻璃的不连续涂层，其中生物活性玻璃颗粒之间的平均间距是预定的，并且在植入患者体内之前至少约20微米。 还公开了生物活性涂层，其包括基底和分布在基底上的纤维和/或生物活性玻璃颗粒，其预定平均纤维间距离为至少约20微米。
-
公开(公告)号：US5990380A
公开(公告)日：1999-11-23
申请号：US948836
申请日：1997-10-10
CPC分类号： A61M39/0247 , A61L29/106 , A61L31/088 , A61B17/00491 , A61F2310/00796 , A61F2310/00928 , A61M2039/0261
摘要： Percutaneous implants are disclosed including a portion implantable into a patient, a dermal bonding region capable of forming a bond between the implant and a dermal layer of the patient after the implantable portion is implanted into the patient, and the dermal bonding region including a substrate with a discontinuous coating of particulate bioactive glass wherein the average spacing between the particles of bioactive glass is predetermined and at least about 20 microns prior to implantation into the patient. Also disclosed are bioactive coatings including a substrate and fibers and/or particles of bioactive glass distributed on the substrate with a predetermined average interfiber distance of at least about 20 microns.
摘要翻译： 公开了经皮植入物，其包括可植入患者体内的部分，在将可植入部分植入患者体内后能够在植入物和患者真皮层之间形成结合的真皮粘合区域，并且真皮粘合区域包括具有 颗粒生物活性玻璃的不连续涂层，其中生物活性玻璃颗粒之间的平均间距是预定的，并且在植入患者体内之前至少约20微米。 还公开了生物活性涂层，其包括基底和分布在基底上的纤维和/或生物活性玻璃颗粒，其预定平均纤维间距离为至少约20微米。
-
公开(公告)号：US08758793B2
公开(公告)日：2014-06-24
申请号：US11431475
申请日：2006-05-10
IPC分类号： A61F2/00
CPC分类号： A61B17/15 , A61B17/06166 , A61B17/68 , A61B17/72 , A61B50/30 , A61B2017/00464 , A61B2017/564 , A61B2050/005 , A61B2050/006 , A61B2090/061 , A61F2/0095 , A61F2/28 , A61F2002/2817 , A61F2002/2825 , A61F2002/30062 , A61F2002/30115 , A61F2002/30116 , A61F2002/30131 , A61F2002/30138 , A61F2002/30159 , A61F2002/30235 , A61F2002/30237 , A61F2002/30238 , A61F2002/30551 , A61F2002/30593 , A61F2002/30616 , A61F2002/30617 , A61F2002/30677 , A61F2002/30714 , A61F2002/30822 , A61F2002/30827 , A61F2002/30828 , A61F2002/30831 , A61F2002/3096 , A61F2002/4658 , A61F2210/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0017 , A61F2230/0028 , A61F2230/0069 , A61F2250/0089 , A61F2250/0097 , A61F2310/00179 , A61F2310/00365 , A61L27/54 , A61L2300/222 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/432 , A61L2300/802
摘要： A therapeutic agent carrier for treating a defect in a bone is disclosed and can include a body that can be configured to approximate a portion of the bone. Further, the therapeutic agent carrier can include a plurality of grooves formed along the body. Each groove can correspond to an incremental length of the body. The therapeutic agent carrier can also include a plurality of dosage stamps along the body and each of the plurality of dosage stamps is adjacent to a corresponding to groove.
摘要翻译： 公开了一种用于治疗骨缺损的治疗剂载体，并且可以包括可构造为近似骨的一部分的主体。 此外，治疗剂载体可以包括沿着身体形成的多个凹槽。 每个凹槽可以对应于身体的增量长度。 治疗剂载体还可以包括沿着身体的多个剂量标记，并且多个剂量标记中的每一个与对应的凹槽相邻。
-
公开(公告)号：US08617585B2
公开(公告)日：2013-12-31
申请号：US11388250
申请日：2006-03-23
IPC分类号： A61F2/00
CPC分类号： A61M25/1011 , A61B17/7061 , A61B17/7098 , A61B17/72 , A61B17/7258 , A61B17/8808 , A61M25/007 , A61M25/0108 , A61M2025/1052
摘要： An intramedullary drug delivery device is disclosed and can be inserted within a bone canal of a bone. The intramedullary drug delivery device can include a housing. A drug delivery region can be established along the housing. Also, the drug delivery region can be configured to substantially span a fracture within the bone.
摘要翻译： 公开了一种髓内药物输送装置，并且可以将其插入到骨的骨管内。 髓内药物递送装置可以包括壳体。 可以沿着房屋建立药物递送区域。 而且，药物递送区域可以构造成基本上跨越骨骼内的骨折。
-
5.发明授权Percutaneous delivery system for treatment of osteonecrosis of the hip and methods of use thereof 有权用于治疗髋关节骨坏死的经皮递送系统及其使用方法公开(公告)号：US08092452B2
公开(公告)日：2012-01-10
申请号：US11751321
申请日：2007-05-21
IPC分类号： A61B17/56
CPC分类号： A61M31/002
摘要： Systems, methods, and carriers for percutaneous delivery of growth factors to treat osteonecrosis in the hip and other locations are disclosed. A rolled carrier comprising a biphasic ceramic rolled by a collagen sponge, and carrying a growth factor, are inserted via a delivery tube or cannula into a pre-formed hole in bone without overstuffing of the carrier or growth factor.
摘要翻译： 公开了用于经皮递送生长因子以治疗髋部和其他位置的骨坏死的系统，方法和载体。 包括由胶原海绵滚动并携带生长因子的双相陶瓷的滚动载体通过输送管或插管插入到骨中的预先形成的孔中，而不会过载载体或生长因子。
-
6.发明申请PERCUTANEOUS DELIVERY SYSTEM FOR TREATMENT OF OSTEONECROSIS OF THE HIP AND METHODS OF USE THEREOF 有权用于治疗呕吐的骨质疏松症的PERCUTANEOUS递送系统及其使用方法公开(公告)号：US20080294085A1
公开(公告)日：2008-11-27
申请号：US11751321
申请日：2007-05-21
IPC分类号： A61M31/00
CPC分类号： A61M31/002
摘要： Systems, methods, and carriers for percutaneous delivery of growth factors to treat osteonecrosis in the hip and other locations are disclosed. A rolled carrier comprising a biphasic ceramic rolled by a collagen sponge, and carrying a growth factor, are inserted via a delivery tube or cannula into a pre-formed hole in bone without overstuffing of the carrier or growth factor.
摘要翻译： 公开了用于经皮递送生长因子以治疗髋部和其他位置的骨坏死的系统，方法和载体。 包括由胶原海绵滚动并携带生长因子的双相陶瓷的滚动载体通过输送管或插管插入到骨中的预先形成的孔中，而不会过载载体或生长因子。
-
公开(公告)号：US08469964B2
公开(公告)日：2013-06-25
申请号：US11431693
申请日：2006-05-10
CPC分类号： A61B17/15 , A61B17/06166 , A61B17/68 , A61B17/72 , A61B50/30 , A61B2017/00464 , A61B2017/564 , A61B2050/005 , A61B2050/006 , A61B2090/061 , A61F2/0095 , A61F2/28 , A61F2002/2817 , A61F2002/2825 , A61F2002/30062 , A61F2002/30115 , A61F2002/30116 , A61F2002/30131 , A61F2002/30138 , A61F2002/30159 , A61F2002/30235 , A61F2002/30237 , A61F2002/30238 , A61F2002/30551 , A61F2002/30593 , A61F2002/30616 , A61F2002/30617 , A61F2002/30677 , A61F2002/30714 , A61F2002/30822 , A61F2002/30827 , A61F2002/30828 , A61F2002/30831 , A61F2002/3096 , A61F2002/4658 , A61F2210/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0017 , A61F2230/0028 , A61F2230/0069 , A61F2250/0089 , A61F2250/0097 , A61F2310/00179 , A61F2310/00365 , A61L27/54 , A61L2300/222 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/432 , A61L2300/802
摘要： A bone cutting template is disclosed and can include a body. A plurality of grooves can be formed along the body and each groove can correspond to an incremental length of the body. The bone cutting template can include a plurality of length stamps along the body. Each of the plurality of length stamps can be adjacent to a corresponding groove.
摘要翻译： 骨切割模板被公开并且可以包括身体。 可以沿着主体形成多个槽，并且每个槽可对应于主体的增量长度。 骨切割模板可以包括沿着身体的多个长度邮票。 多个长度标记中的每一个可以与相应的凹槽相邻。
-
公开(公告)号：US06274159B1
公开(公告)日：2001-08-14
申请号：US09429396
申请日：1999-10-28
IPC分类号： A61F202
CPC分类号： A61K9/0024 , A61K9/0039 , C03C3/097 , C03C10/0009
摘要： An improved implantable pharmaceutical depot for the prolonged release of at least one biologically active substance, the depot comprising a polymeric carrier and the biologically active substance, the improvement wherein the depot is coated or surface modified with a biologically active and biocompatible glass, glass-ceramic or ceramic material, the coating or modified surface being capable of forming a bond to soft tissue upon implantation. Methods for forming the biologically active and biocompatible glass, glass-ceramic or ceramic coating or modified surface on the silicone based depot are also disclosed.
摘要翻译： 用于延长释放至少一种生物活性物质的改进的可植入药物贮库，所述贮存库包含聚合物载体和所述生物活性物质，其改进在于使用生物活性和生物相容性玻璃，玻璃陶瓷 或陶瓷材料，所述涂层或改性表面能够在植入时与软组织形成结合。 还公开了在硅氧烷基储存库上形成生物活性和生物相容性玻璃，玻璃陶瓷或陶瓷涂层或改性表面的方法。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.025 秒)
