公开(公告)号：US4288367A

公开(公告)日：1981-09-08

申请号：US201106

申请日：1980-10-28

Applicant: Janet A. Day ,  Robert J. G. Searle

Inventor： Janet A. Day ,  Robert J. G. Searle

IPC: A01H3/04 ,  A01N43/38 ,  C07D209/52

CPC classification number: C07D209/52 ,  A01N43/38

Abstract: 2-cyano-2-carboxy-3-azabicyclo[3.1.0]hexane, hydrates, esters, and salts thereof, useful as pollen-suppressants.

Abstract translation: 2-氰基-2-羧基-3-氮杂双环[3.1.0]己烷，其水合物，酯和盐，可用作花粉抑制剂。

公开(公告)号：US4372776A

公开(公告)日：1983-02-08

申请号：US312039

申请日：1981-10-16

Applicant: Janet A. Day ,  Robert J. G. Searle

Inventor： Janet A. Day ,  Robert J. G. Searle

IPC: A01N53/00 ,  A01N53/10 ,  A01N53/12 ,  A01N55/10 ,  C07C67/00 ,  C07C227/00 ,  C07C227/06 ,  C07C229/48 ,  C07C231/00 ,  C07C231/12 ,  C07C237/24 ,  C07C241/00 ,  C07C243/06 ,  C07C243/36 ,  C07C253/00 ,  C07C255/29 ,  C07C325/00 ,  C07C327/14 ,  C07C327/24 ,  C07D203/14 ,  C07D307/52 ,  C07D333/20 ,  C07D333/24 ,  C07F7/10 ,  A01N43/10 ,  C07C69/74 ,  C07C121/78

CPC classification number: C07D333/20 ,  A01N53/00 ,  C07D333/24

Abstract: Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.3 each is hydrogen or R.sup.1 and R.sup.3 together form a second carbon-to-nitrogen bond, R.sup.2 is hydrogen or cyano, R.sup.4 is alkyl and Ar is one of certain aromatic moieties.The compounds can be used as abscission agents for the loosening of fruit and/or leaves on plants.

Abstract translation: 式（I）的化合物其中R 1和R 3各自为氢或R 1和R 3一起形成第二碳 - 氮键，R 2为氢或氰基，R 4为烷基，Ar为某些芳族部分之一。 该化合物可用作植物上水果和/或叶子松动的脱落剂。

公开(公告)号：US4254057A

公开(公告)日：1981-03-03

申请号：US114790

申请日：1980-01-24

Applicant: Janet A. Day ,  Barry R. J. Devlin ,  Robert J. G. Searle

Inventor： Janet A. Day ,  Barry R. J. Devlin ,  Robert J. G. Searle

IPC: C07D209/52 ,  C07C87/34

CPC classification number: C07C255/00 ,  C07D209/52

Abstract: 3-azabicyclo(3.1.0)hexane-2-carboxylic acid, a plant gametocide, is prepared by effecting reaction between cis 2-aminomethylcyclopropyl-1,1-dimethyl acetal and a cyanide in the presence of a liquid lower-alkanecarboxylic acid; treating the resulting N-alkanoyl-3-azabicyclo(2.1.0)hexane-2-carbonitrile with a strong acid; treating the resulting 3-alkanoyl-3-azabicyclo(3.1.0)hexane-2-carboxylic acid with strong acid to form the desired 3-azabicyclo(3.1.0)hexane-2-carboxylic acid.

Abstract translation: 通过在液体低级链烷羧酸的存在下进行顺式2-氨基甲基环丙基-1,1-二甲基缩醛与氰化物之间的反应制备3-氨基二氮杂双环（3.1.0）己烷-2-羧酸， 用强酸处理得到的N-烷酰基-3-氮杂双环（2.1.0）己烷-2-腈; 用强酸处理所得的3-链烷酰基-3-氮杂双环（3.1.0）己烷-2-羧酸，形成所需的3-氮杂双环（3.1.0）己烷-2-羧酸。

公开(公告)号：US4249936A

公开(公告)日：1981-02-10

申请号：US101992

申请日：1979-12-07

Applicant: Robert J. G. Searle ,  Janet A. Day

Inventor： Robert J. G. Searle ,  Janet A. Day

IPC: A01N43/38 ,  C07D209/52

CPC classification number: C07D209/52 ,  A01N43/38

Abstract: Esters of 2-carboxy-3-azabicyclo(3.1.0)hex-2-ene, useful as intermediates to the cis-racemate of methanoproline, and as inhibitors of pollen formation in cereal grains.

Abstract translation: 2-羧基-3-氮杂双环（3.1.0）己-2-烯的酯可用作甲基蓖麻的顺式外消旋物的中间体，并且作为谷物中花粉形成的抑制剂。

公开(公告)号：US4279821A

公开(公告)日：1981-07-21

申请号：US165996

申请日：1980-07-07

Applicant: Janet A. Day ,  Barry R. J. Devlin ,  Robert J. G. Searle

Inventor： Janet A. Day ,  Barry R. J. Devlin ,  Robert J. G. Searle

IPC: C07D209/52

CPC classification number: C07C255/00 ,  C07D209/52

Abstract: 3-Azabicyclo(3.1.0)hexane-2-carboxylic acid, a plant gametocide, is prepared by effecting reaction between cis 2-aminomethylcyclopropyl-1,1-dimethyl acetal and a cyanide in the presence of a liquid lower-alkanecarboxylic acid; treating the resulting N-alkanoyl-3-azabicyclo(2.1.0)hexane-2-carbonitrile with a strong acid; treating the resulting 3-alkanoyl-3-azabicyclo(3.1.0)hexane-2-carboxylic acid with strong acid to form the desired 3-azabicyclo(3.1.0)hexane-2-carboxylic acid.

公开(公告)号：US4255334A

公开(公告)日：1981-03-10

申请号：US49374

申请日：1979-06-18

Applicant: Janet A. Day ,  Barry R. J. Devlin ,  Robert J. G. Searle

Inventor： Janet A. Day ,  Barry R. J. Devlin ,  Robert J. G. Searle

IPC: C07D209/52 ,  C07D207/20 ,  C07D207/22

CPC classification number: C07C255/00 ,  C07D209/52

Abstract: 3-Azabicyclo(3.1.0)hexane-2-carboxylic acid, a plant gametocide, is prepared by effecting reaction between cis 2-aminomethylcyclopropyl-1,1-dimethyl acetal and a cyanide in the presence of a liquid lower-alkanecarboxylic acid; treating the resulting N-alkanoyl-3-azabicyclo(2.1.0)hexane-2-carbonitrile with a strong acid; treating the resulting 3-alkanoyl-3-azabicyclo(3.1.0)hexane-2-carboxylic acid with strong acid to form the desired 3-azabicyclo(3.1.0)hexane-2-carboxylic acid.

公开(公告)号：US4012522A

公开(公告)日：1977-03-15

申请号：US611758

申请日：1975-09-09

Applicant: Robert J. G. Searle ,  Roger E. Woodall

Inventor： Robert J. G. Searle ,  Roger E. Woodall

IPC: A01N53/08 ,  C07C69/74 ,  A01N9/24

CPC classification number: C07C69/74

Abstract: Cyclopropane derivatives of the formula: ##STR1## wherein each R, R.sub.1, and R.sub.2 is alkyl, R.sub.3 is optionally substituted hydrocarbyl, and Z is optionally substituted phenyl are useful as pesticides.

Abstract translation: 下式的环丙烷衍生物：其中每个R 1，R 2和R 2是烷基，R 3是任选取代的烃基，Z是任选取代的苯基，可用作农药。

公开(公告)号：US3973035A

公开(公告)日：1976-08-03

申请号：US589284

申请日：1975-06-23

Applicant: Robert J. G. Searle ,  Roger E. Woodall ,  Michael J. Bull

Inventor： Robert J. G. Searle ,  Roger E. Woodall ,  Michael J. Bull

IPC: A01N9/06 ,  A01N9/20

Abstract: New cyanobenzyl cyclopropane carboxylates of the formula: ##EQU1## where Hal represents a halogen atom; R.sub.1 and R.sub.2 each represent an alkyl group; and X represent an optionally substituted phenyl group are useful as pesticides.

Abstract translation: 新的氰基苄基环丙烷羧酸盐，其分子式如下：HalHal ANGLE ANGLE R1 ------H R2COOCH-X | CN其中Hal表示卤素原子; R1和R2各自表示烷基; 和X代表任选取代的苯基可用作杀虫剂。

公开(公告)号：US4042710A

公开(公告)日：1977-08-16

申请号：US687483

申请日：1976-05-18

Applicant: Michael J. Bull ,  Robert J. G. Searle

Inventor： Michael J. Bull ,  Robert J. G. Searle

IPC: C07C69/533 ,  A01N37/00 ,  A01N37/02 ,  A01N37/30 ,  A01N37/32 ,  A01N37/34 ,  A01N37/36 ,  A01N37/46 ,  A01N43/08 ,  A61K38/095 ,  C07C51/08 ,  C07C51/38 ,  C07C67/00 ,  C07C69/00 ,  C07C69/24 ,  C07C69/612 ,  C07C253/00 ,  C07C255/38 ,  C07C255/53 ,  C07C325/00 ,  C07C327/44 ,  C07D209/49 ,  C07D307/42 ,  A01N9/20 ,  C07C121/66

CPC classification number: C07C255/00 ,  C07C51/08 ,  C07C51/38 ,  C07C69/24 ,  C07C69/612 ,  C07C69/708

Abstract: Compounds of the formula ##STR1## wherein R is alkenyl, aralkyl or alkyl; X is H, CN, thioamide, or alkynyl; and Y is phenoxyphenyl or phthalimido, are useful as pesticides.

Abstract translation: 其中R为烯基，芳烷基或烷基的式IMA化合物; X是H，CN，硫代酰胺或炔基; Y是苯氧基苯基或邻苯二甲酰亚氨基，可用作农药。

公开(公告)号：US4175134A

公开(公告)日：1979-11-20

申请号：US898367

申请日：1978-04-17

Applicant: Royston H. Davis ,  Robert J. G. Searle

Inventor： Royston H. Davis ,  Robert J. G. Searle

IPC: A01N37/38 ,  A01N53/00 ,  A01N9/12 ,  C07C153/11

CPC classification number: A01N53/00 ,  A01N37/38

Abstract: Certain esters of alpha-substituted-phenoxybenzyl alcohols of the formula ##STR1## wherein A represents certain optionally substituted aralkyl, alkyl or cyclopropyl groups at least one of X and Y is sulfur and the other independently represents oxygen or sulfur and R represents certain alkyl, alkenyl, alkynyl, aralkyl, alkaryl or aryl groups, hydrogen or a salt-forming cation, are useful as pesticides.

Abstract translation: 其中A代表某些任选取代的芳烷基，烷基或环丙基，X和Y中的至少一个是硫，另一个独立地表示氧或硫，R表示某些烷基， 烯基，炔基，芳烷基，烷芳基或芳基，氢或成盐阳离子可用作杀虫剂。