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公开(公告)号:US20240262921A1
公开(公告)日:2024-08-08
申请号:US18643356
申请日:2024-04-23
发明人: Ricardo ATTAR , Rajkumar Ganesan , Francois Gaudet , Bradley J. Heidrich , Carmen Baca Jones , John Lee , Yingzhe Li , Sanjaya Singh , Sathya Venkataramani
CPC分类号: C07K16/2866 , A61K9/0019 , A61P35/00 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/24 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/74 , C07K2319/02 , C07K2319/03 , C07K2319/30 , C07K2319/33
摘要: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
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公开(公告)号:US12077592B2
公开(公告)日:2024-09-03
申请号:US16743188
申请日:2020-01-15
发明人: Ricardo Attar , Rajkumar Ganesan , Francois Gaudet , Bradley J. Heidrich , Carmen Baca Jones , John Lee , Yingzhe Li , Sanjaya Singh , Sathya Venkataramani
CPC分类号: C07K16/2866 , A61K9/0019 , A61P35/00 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/24 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/74 , C07K2319/02 , C07K2319/03 , C07K2319/30 , C07K2319/33
摘要: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
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公开(公告)号:US20240228618A1
公开(公告)日:2024-07-11
申请号:US18561512
申请日:2022-05-16
CPC分类号: C07K16/2809 , A61P35/02 , C07K16/2842 , C07K16/2866 , C07K16/2884 , A61K2039/507 , A61K2039/545 , C07K2317/31 , C07K2317/56 , C07K2317/76
摘要: Disclosed herein is a pharmaceutical composition comprising a T cell redirect therapeutic and an anti-CD44 therapeutic, and uses thereof for killing cancer cells.
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公开(公告)号:US20200231686A1
公开(公告)日:2020-07-23
申请号:US16743188
申请日:2020-01-15
发明人: Ricardo Attar , Rajkumar Ganesan , Francois Gaudet , Bradley J. Heidrich , Carmen Baca Jones , John Lee , Yingzhe Li , Sanjaya Singh , Sathya Venkataramani
摘要: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
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