公开(公告)号：US20230151083A1

公开(公告)日：2023-05-18

申请号：US17917916

申请日：2021-04-07

Applicant: Janssen Biotech, Inc.

Inventor： Kristof Van Kolen ,  Marc Mercken ,  Rupesh Nanjunda ,  Sanjaya Singh ,  Sherry La Porte ,  Jinquan Luo ,  Pharavee Jaiprasart ,  Sathya Venkataramani ,  Rajkumar Ganesan

IPC: C07K16/18 ,  G01N33/68 ,  A61P25/28 ,  C12N15/63

CPC classification number: C07K16/18 ,  G01N33/6896 ,  A61P25/28 ,  C12N15/63 ,  C07K2317/56

Abstract: Monoclonal anti-PHF-tau antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies and using the antibodies for treating or preventing conditions such as tauopathies.

公开(公告)号：US20200231686A1

公开(公告)日：2020-07-23

申请号：US16743188

申请日：2020-01-15

Applicant: Janssen Biotech, Inc.

Inventor： Ricardo Attar ,  Rajkumar Ganesan ,  Francois Gaudet ,  Bradley J. Heidrich ,  Carmen Baca Jones ,  John Lee ,  Yingzhe Li ,  Sanjaya Singh ,  Sathya Venkataramani

IPC: C07K16/28 ,  A61P35/00 ,  A61K9/00

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.

公开(公告)号：US12077592B2

公开(公告)日：2024-09-03

申请号：US16743188

申请日：2020-01-15

Applicant: Janssen Biotech, Inc.

Inventor： Ricardo Attar ,  Rajkumar Ganesan ,  Francois Gaudet ,  Bradley J. Heidrich ,  Carmen Baca Jones ,  John Lee ,  Yingzhe Li ,  Sanjaya Singh ,  Sathya Venkataramani

IPC: C07K16/28 ,  A61K9/00 ,  A61P35/00 ,  A61K39/00

CPC classification number: C07K16/2866 ,  A61K9/0019 ,  A61P35/00 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/545 ,  C07K2317/24 ,  C07K2317/53 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/74 ,  C07K2319/02 ,  C07K2319/03 ,  C07K2319/30 ,  C07K2319/33

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.

公开(公告)号：US20240262921A1

公开(公告)日：2024-08-08

申请号：US18643356

申请日：2024-04-23

Applicant: Janssen Biotech, Inc.

Inventor： Ricardo ATTAR ,  Rajkumar Ganesan ,  Francois Gaudet ,  Bradley J. Heidrich ,  Carmen Baca Jones ,  John Lee ,  Yingzhe Li ,  Sanjaya Singh ,  Sathya Venkataramani

IPC: C07K16/28 ,  A61K9/00 ,  A61K39/00 ,  A61P35/00

CPC classification number: C07K16/2866 ,  A61K9/0019 ,  A61P35/00 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/545 ,  C07K2317/24 ,  C07K2317/53 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/74 ,  C07K2319/02 ,  C07K2319/03 ,  C07K2319/30 ,  C07K2319/33

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.