公开(公告)号：US20220064254A1

公开(公告)日：2022-03-03

申请号：US16936719

申请日：2020-07-23

Applicant: Janssen Biotech, Inc.

Inventor： Raymond BRITTINGHAM ,  Rajkumar GANESAN ,  Sherry LA PORTE ,  John T. LEE ,  Jinquan LUO ,  Theresa MCDEVITT ,  Fei SHEN ,  Sanjaya SINGH ,  Degang SONG ,  Sathyadevi VENKATARAMANI ,  Fang YI ,  Yonghong ZHAO

IPC: C07K14/725 ,  A61K35/17 ,  C07K16/40 ,  C07K14/705

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for the treatment of cancer.