公开(公告)号：US20240409634A1

公开(公告)日：2024-12-12

申请号：US18691254

申请日：2022-09-12

Applicant: Janssen Biotech, Inc.

Inventor： Patrick John DOONAN ,  Sherry Lynn LA PORTE ,  Sanjaya SINGH ,  Paul Willem Henri lda PARREN ,  Sabrina Julia Louisa MERAT ,  Robertus Cornelis ROOVERS ,  Sara Mohamed A ELASHKAR ,  Ulrike PHILIPPAR

IPC: C07K16/28 ,  A61P35/02

Abstract: The invention relates to multispecific antibodies and pharmaceutical compositions comprising said antibodies, to processes for the preparation of said antibodies and to the use of said antibodies targeting CD33 and to their use in the treatment of diseases, e.g., cancer.

公开(公告)号：US20210145878A1

公开(公告)日：2021-05-20

申请号：US16950296

申请日：2020-11-17

Applicant: JANSSEN BIOTECH, INC.

Inventor： Rajkumar GANESAN ,  Elena LASORSA ,  Ulrike PHILIPPAR

IPC: A61K35/17 ,  A61P35/00 ,  C07K16/28

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a Cluster of Differentiation 79b protein (CD79b), and immunoresponsive cells comprising such CARs, for the treatment of cancer.