公开(公告)号：US20200173925A1

公开(公告)日：2020-06-04

申请号：US16496197

申请日：2018-03-28

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroyuki NOJI ,  Kazuhito TABATA

IPC: G01N21/64 ,  G01N21/31 ,  G01N1/36

Abstract: Provided is a method of enclosing a microscopic body in at least some of a plurality of cavities formed in the surface of a substrate, including the step of arranging an insertion member above the cavity-formed surface of the substrate, determining relative positions of the insertion member and the substrate by a support section provided on the insertion member such that the bottom surface of the insertion member and the cavity-formed surface of the substrate face each other, thereby providing a solution introduction space between the bottom surface of the insertion member and the cavity-formed surface of the substrate, and providing a solution discharge space that is in communication with the solution introduction space, the solution discharge space being located above the bottom surface of the insertion member, and between the substrate and the insertion member, within the substrate and/or within the insertion member.

公开(公告)号：US20190194717A1

公开(公告)日：2019-06-27

申请号：US16329829

申请日：2017-09-04

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroyuki NOJI ,  Kazuhito TABATA

IPC: C12Q1/34

CPC classification number: C12Q1/34 ,  C12M1/34 ,  C12Q1/04 ,  C12Q1/70 ,  C12Q2334/22 ,  G01N33/483 ,  G01N2333/924 ,  Y02A50/451 ,  Y02A50/53 ,  Y02A50/60

Abstract: Provided is a method for detecting pathogenic microorganisms in a biological sample, which is a technique that can be used to perform high-sensitivity detection of pathogenic microorganisms, such as influenza virus, etc.

公开(公告)号：US20220145407A1

公开(公告)日：2022-05-12

申请号：US17435629

申请日：2020-03-05

Applicant: Japan Science and Technology Agency

Inventor： Kazuhito TABATA ,  Hiroyuki NOJI ,  Yasuteru URANO ,  Mako KAMIYA

IPC: C12Q1/70 ,  C12Q1/40 ,  G01N21/64

Abstract: As a technique for detecting an influenza virus with an improved accuracy, there is provided a method for detecting an influenza virus in a biological sample by using a first probe, which is decomposed by an influenza virus-derived neuraminidase and a bacterium-derived neuraminidase to generate an optically detectable signal, and a second probe, which is decomposed by the bacterium-derived neuraminidase to generate an optically detectable signal and not decomposed by the influenza virus-derived neuraminidase.