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1.发明申请Povidone Iodine, A Novel Alternative Preservative For Ophthalmic Compositions 审中-公开聚维酮碘，眼科组合物的新型替代防腐剂公开(公告)号：US20120027716A1
公开(公告)日：2012-02-02
申请号：US12997374
申请日：2009-06-10
申请人： Jason Stein , Bo Liang , C. Michael Samson , Joseph A. Capriotti , Michael Weiser , Mark B. Abelson
发明人： Jason Stein , Bo Liang , C. Michael Samson , Joseph A. Capriotti , Michael Weiser , Mark B. Abelson
CPC分类号： A01N43/36 , A61K9/0048 , A61K31/56 , A61K31/79 , A61K45/06 , A61L12/105 , A61K2300/00
摘要： The invention includes a preserved ophthalmic preparation comprising povidone-iodine (PVP-I) at a concentration sufficient to preserve the ophthalmic preparation, and at least one member selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antibacterial compound, an anti-allergy compound, and an anti-glaucoma compound. The invention also includes adding PVP-I to an ophthalmic composition in order to preserve the composition, wherein the PVP-I is added at a concentration sufficient to preserve the composition.
摘要翻译： 本发明包括含有足以保护眼用制剂的浓度的聚维酮碘（PVV-I）的保存眼用制剂，以及选自甾族抗炎化合物，非甾体抗炎药物， 炎性化合物，抗菌化合物，抗过敏化合物和抗青光眼化合物。 本发明还包括向眼用组合物中加入PVP-1以保留组合物，其中以足以保留组合物的浓度加入PVP-1。
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公开(公告)号：US20130177522A1
公开(公告)日：2013-07-11
申请号：US13515987
申请日：2010-12-15
CPC分类号： A61K47/10 , A61K9/0048 , A61K31/74 , A61K31/79 , A61K33/18 , A61K45/06 , A61K47/08 , A61K47/32 , A61K2300/00
摘要： Disclosed are compositions and methods comprising povidone-iodine and a cooling-effective amount of a chemical agent. The compositions are useful to relieve mild ocular irritation, enhance ocular comfort, and to provide a refreshing effect and improved sensation, when the povidone-iodine solution is applied to the eye.
摘要翻译： 公开了包含聚维酮碘和冷却有效量的化学试剂的组合物和方法。 当将聚维酮碘溶液施用于眼睛时，该组合物可用于缓解轻度眼睛刺激，增强眼睛舒适度，并提供清爽效果和改善的感觉。
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3.发明申请Otic compositions for the treatment of infections of the internal and external ear in mammals 审中-公开用于治疗哺乳动物内耳和外耳感染的耳用组合物公开(公告)号：US20090263345A1
公开(公告)日：2009-10-22
申请号：US12380463
申请日：2009-02-27
CPC分类号： A61K31/79 , A61K9/0031 , A61K9/0046 , A61K9/06 , A61K31/573 , A61K2300/00
摘要： Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
摘要翻译： 本文公开了包含聚维酮碘（PVP-1）的组合物，其可用于治疗哺乳动物（包括人）的内部，中部和外部的耳朵的急性和慢性细菌，病毒和真菌感染。
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4.发明申请STABLE POVIDONE-IODINE COMPOSITIONS WITH STEROIDS OR NON-STEROIDAL ANTI-INFLAMMATORIES 审中-公开稳定的POVIDONE-IODINE组合物与非甾体抗炎药物或非甾体抗炎药公开(公告)号：US20150038473A1
公开(公告)日：2015-02-05
申请号：US14117086
申请日：2012-05-11
IPC分类号： A61K31/573 , A61K9/00 , A61K31/196 , A61K31/56 , A61K47/34
CPC分类号： A61K31/573 , A61K9/0048 , A61K31/196 , A61K31/56 , A61K31/79 , A61K47/34 , A61K2300/00
摘要： Disclosed are stable compositions comprising povidone-iodine and a steroid, and methods of making and using such compositions. Also disclosed herein are stable compositions comprising povidone-iodine and an NSAID, and methods of making and using such compositions.
摘要翻译： 公开了包含聚维酮碘和类固醇的稳定组合物，以及制备和使用这些组合物的方法。 本文还公开了包含聚维酮碘和NSAID的稳定组合物，以及制备和使用这些组合物的方法。
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5.发明申请OTIC COMPOSITIONS FOR THE TREATMENT OF INFECTIONS OF THE INTERNAL AND EXTERNAL EAR IN MAMMALS 审中-公开用于治疗哺乳动物内部和外部感染的OTIC组合物公开(公告)号：US20120003174A1
公开(公告)日：2012-01-05
申请号：US13234978
申请日：2011-09-16
CPC分类号： A61K31/79 , A61K9/0031 , A61K9/0046 , A61K9/06 , A61K31/573 , A61K2300/00
摘要： Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
摘要翻译： 本文公开了包含聚维酮碘（PVP-1）的组合物，其可用于治疗哺乳动物（包括人）的内部，中部和外部的耳朵的急性和慢性细菌，病毒和真菌感染。
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6.发明申请OTIC COMPOSITIONS FOR THE TREATMENT OF INFECTIONS OF THE INTERNAL AND EXTERNAL EAR IN MAMMALS 审中-公开用于治疗哺乳动物内部和外部感染的OTIC组合物公开(公告)号：US20130089510A1
公开(公告)日：2013-04-11
申请号：US13466763
申请日：2012-05-08
IPC分类号： A61K31/79 , A61K31/573
CPC分类号： A61K31/79 , A61K9/0031 , A61K9/0046 , A61K9/06 , A61K31/573 , A61K2300/00
摘要： Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
摘要翻译： 本文公开了包含聚维酮碘（PVP-1）的组合物，其可用于治疗哺乳动物（包括人）的内部，中部和外部的耳朵的急性和慢性细菌，病毒和真菌感染。
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公开(公告)号：US07767217B2
公开(公告)日：2010-08-03
申请号：US11636293
申请日：2006-12-07
申请人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
发明人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
CPC分类号： A61K31/79 , A61K9/0048 , A61K31/192 , A61K31/196 , A61K31/24 , A61K31/245 , A61K31/407 , A61K31/4535 , A61K31/56 , A61K31/573 , A61K31/80 , A61K33/18 , A61K45/06 , A61K47/02 , A61K47/183 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.
摘要翻译： 由聚维酮碘0.01％至10.0％与类固醇或非甾体抗炎药组合的局部眼用组合物。 该溶液可用于治疗来自细菌，分枝杆菌，病毒，真菌或阿米巴病原体的至少一种眼组织（例如结膜和角膜）的活性感染，以及在适当的临床环境中预防这种感染的治疗 （例如角膜磨损，术后预防，LASIK / LASEK后期预防）。 此外，该解决方案可有效预防术后眼科患者的感染和炎症。
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公开(公告)号：US08562963B2
公开(公告)日：2013-10-22
申请号：US12814836
申请日：2010-06-14
申请人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
发明人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
IPC分类号： A61K31/74
CPC分类号： A61K31/79 , A61K9/0048 , A61K31/192 , A61K31/196 , A61K31/24 , A61K31/245 , A61K31/407 , A61K31/4535 , A61K31/56 , A61K31/573 , A61K31/80 , A61K33/18 , A61K45/06 , A61K47/02 , A61K47/183 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.
摘要翻译： 由聚维酮碘0.01％至10.0％与类固醇或非甾体抗炎药组合的局部眼用组合物。 该溶液可用于治疗来自细菌，分枝杆菌，病毒，真菌或阿米巴病原体的至少一种眼组织（例如结膜和角膜）的活性感染，以及在适当的临床环境中预防这种感染的治疗 （例如角膜磨损，术后预防，LASIK / LASEK后期预防）。 此外，该解决方案可有效预防术后眼科患者的感染和炎症。
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公开(公告)号：US08394364B2
公开(公告)日：2013-03-12
申请号：US12845544
申请日：2010-07-28
申请人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
发明人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
CPC分类号： A61K31/79 , A61K9/0048 , A61K31/192 , A61K31/196 , A61K31/24 , A61K31/245 , A61K31/407 , A61K31/4535 , A61K31/56 , A61K31/573 , A61K31/80 , A61K33/18 , A61K45/06 , A61K47/02 , A61K47/183 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.
摘要翻译： 由聚维酮碘0.01％至10.0％与类固醇或非甾体抗炎药组合的局部眼用组合物。 该溶液可用于治疗来自细菌，分枝杆菌，病毒，真菌或阿米巴病原体的至少一种眼组织（例如结膜和角膜）的活性感染，以及在适当的临床环境中预防这种感染的治疗 （例如角膜磨损，术后预防，LASIK / LASEK后期预防）。 此外，该解决方案可有效预防术后眼科患者的感染和炎症。
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公开(公告)号：US20100291019A1
公开(公告)日：2010-11-18
申请号：US12845544
申请日：2010-07-28
申请人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
发明人： C. Michael Samson , Bo Liang , Joseph A. Capriotti
CPC分类号： A61K31/79 , A61K9/0048 , A61K31/192 , A61K31/196 , A61K31/24 , A61K31/245 , A61K31/407 , A61K31/4535 , A61K31/56 , A61K31/573 , A61K31/80 , A61K33/18 , A61K45/06 , A61K47/02 , A61K47/183 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.
摘要翻译： 由聚维酮碘0.01％至10.0％与类固醇或非甾体抗炎药组合的局部眼用组合物。 该溶液可用于治疗来自细菌，分枝杆菌，病毒，真菌或阿米巴病原体的至少一种眼组织（例如结膜和角膜）的活性感染，以及在适当的临床环境中预防这种感染的治疗 （例如角膜磨损，术后预防，LASIK / LASEK后期预防）。 此外，该解决方案可有效预防术后眼科患者的感染和炎症。
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