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公开(公告)号：US07803790B2
公开(公告)日：2010-09-28
申请号：US11431942
申请日：2006-05-09
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Anu Mahadevan , Peter Meltzer , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Anu Mahadevan , Peter Meltzer , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
IPC分类号： A61K31/33 , A61K31/425 , C07D277/60
CPC分类号： A61K31/4709 , A61K9/0014 , A61K9/0053 , A61K31/427 , A61K31/47 , A61K31/498 , A61K31/506 , A61K31/538 , A61K31/55 , C07D215/54 , C07D409/04 , C07D495/04
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。
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公开(公告)号：US20100152209A1
公开(公告)日：2010-06-17
申请号：US12084610
申请日：2006-11-03
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Anu Mahadevan , Peter Meltzer , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Anu Mahadevan , Peter Meltzer , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
IPC分类号： A61K31/517 , A61K31/519 , C07D239/72 , A61P25/00 , A61P17/02 , A61P29/00 , A61P17/06 , A61P25/06 , A61P19/10 , A61P1/00
CPC分类号： C07D487/04 , A61K31/517 , C07D239/91 , C07D401/06 , C07D471/04
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。
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公开(公告)号：US20150299225A1
公开(公告)日：2015-10-22
申请号：US14542089
申请日：2014-11-14
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen , Anu Mahadevan , Peter Meltzer
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen , Anu Mahadevan , Peter Meltzer
IPC分类号： C07D513/04 , A61K8/49 , A61K31/428 , A61K31/4709 , A61K31/55 , A61K31/498 , A61K31/538 , C07D215/08 , C07D223/16 , C07D277/70 , C07D417/12 , C07D401/12 , C07D413/12 , C07D409/14 , A61Q7/02 , A61K31/47
CPC分类号： C07D513/04 , A61K8/49 , A61K8/4906 , A61K8/4926 , A61K31/428 , A61K31/47 , A61K31/4709 , A61K31/498 , A61K31/538 , A61K31/55 , A61Q7/02 , C07D215/08 , C07D223/16 , C07D277/70 , C07D401/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。
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公开(公告)号：US08916550B2
公开(公告)日：2014-12-23
申请号：US11600514
申请日：2006-11-15
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen , Anu Mahadevan , Peter Meltzer
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen , Anu Mahadevan , Peter Meltzer
IPC分类号： A61K31/55 , A61K31/47 , A61K31/40 , A61K31/165 , A61K31/428 , C07D417/12 , C07D513/04 , C07D401/12 , A61K31/4709
CPC分类号： C07D513/04 , A61K8/49 , A61K8/4906 , A61K8/4926 , A61K31/428 , A61K31/47 , A61K31/4709 , A61K31/498 , A61K31/538 , A61K31/55 , A61Q7/02 , C07D215/08 , C07D223/16 , C07D277/70 , C07D401/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。
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公开(公告)号：US20110144135A1
公开(公告)日：2011-06-16
申请号：US13022107
申请日：2011-02-07
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Anu Mahadevan , Peter Meltzer , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Anu Mahadevan , Peter Meltzer , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
IPC分类号： A61K31/519 , C07D487/04 , A61P43/00
CPC分类号： C07D487/04 , A61K31/517 , C07D239/91 , C07D401/06 , C07D471/04
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。
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6.发明授权Substituted pyrimido 4.5-d pyrimidin-4-one compounds for modulating TRPV3 function 有权用于调节TRPV3功能的取代的嘧啶基4.5-d嘧啶-4-酮化合物公开(公告)号：US08552009B2
公开(公告)日：2013-10-08
申请号：US13022107
申请日：2011-02-07
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Magdalene M. Moran , Amy S. Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen , Anu Mahadevan , Peter Meltzer
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Magdalene M. Moran , Amy S. Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen , Anu Mahadevan , Peter Meltzer
IPC分类号： A61K31/519
CPC分类号： C07D487/04 , A61K31/517 , C07D239/91 , C07D401/06 , C07D471/04
摘要： The present application relates to compounds of Formula I as defined herein, and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及本文定义的式I化合物，以及用于治疗与TRPV3有关的疼痛和其它病症的方法。
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7.发明授权公开(公告)号：US07893260B2
公开(公告)日：2011-02-22
申请号：US11592783
申请日：2006-11-03
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, Jr. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
IPC分类号： C07D239/72
CPC分类号： C07D487/04 , A61K31/517 , C07D239/91 , C07D401/06 , C07D471/04
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3. Suitable compounds include but are not limited to, for example, substituted quinazolin-4-ones of formula I.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。 合适的化合物包括但不限于例如式I的取代喹唑啉-4-酮。
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公开(公告)号：US20100273777A1
公开(公告)日：2010-10-28
申请号：US12755118
申请日：2010-04-06
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , William C. Lumma, JR. , Magdalene M. Moran , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
IPC分类号： A61K31/55 , A61K31/47 , A61K31/428 , A61K31/4709 , A61K31/538 , A61K31/498 , A61P29/00 , C12N5/02
CPC分类号： A61K31/4709 , A61K9/0014 , A61K9/0053 , A61K31/427 , A61K31/47 , A61K31/498 , A61K31/506 , A61K31/538 , A61K31/55 , C07D215/54 , C07D409/04 , C07D495/04
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
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公开(公告)号：US20120015979A1
公开(公告)日：2012-01-19
申请号：US13175366
申请日：2011-07-01
申请人： Magdalene M. Moran , Jayhong A. Chong , Christopher Fanger , Amy Ripka , Glenn R. Larsen , Xiaoguang Zhen , Dennis John Underwood , Manfred Weigele
发明人： Magdalene M. Moran , Jayhong A. Chong , Christopher Fanger , Amy Ripka , Glenn R. Larsen , Xiaoguang Zhen , Dennis John Underwood , Manfred Weigele
IPC分类号： A61K31/4709 , A61P17/02 , A61P29/00 , A61P3/10 , A61P17/06 , A61P17/00 , A61P25/06 , A61P1/00 , A61P37/00 , A61P19/02 , A61P11/14 , A61Q7/02 , A61P17/10 , A61Q19/08 , A61P35/00 , A61P31/10 , A61P31/12 , A61P31/00 , A61P17/12 , A61P25/00
CPC分类号： A61K31/4709 , C07D401/12
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
摘要翻译： 本申请涉及用于治疗与TRPV3相关的疼痛和其它病症的化合物和方法。
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公开(公告)号：US09486455B2
公开(公告)日：2016-11-08
申请号：US13040859
申请日：2011-03-04
申请人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , Magdalene M. Moran , Howard Ng , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
发明人： Jayhong A. Chong , Christopher Fanger , Glenn R. Larsen , Magdalene M. Moran , Howard Ng , Amy Ripka , Dennis John Underwood , Manfred Weigele , Xiaoguang Zhen
IPC分类号： A01N43/58 , A01N43/60 , A61K31/517 , A61K31/519
CPC分类号： A61K31/519 , A61K31/517
摘要： The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
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