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公开(公告)号:US07713996B2
公开(公告)日:2010-05-11
申请号:US11519485
申请日:2006-09-12
申请人: Jean Ackermann , Konrad Bleicher , Simona M Ceccarelli Grenz , Odile Chomienne , Patrizio Mattei , Tanja Schulz-Gasch
发明人: Jean Ackermann , Konrad Bleicher , Simona M Ceccarelli Grenz , Odile Chomienne , Patrizio Mattei , Tanja Schulz-Gasch
IPC分类号: A61K31/404 , A61K31/47 , C07D209/04 , C07D215/00
CPC分类号: C07D223/16 , C07D209/10 , C07D215/58 , C07D403/12 , C07D413/12
摘要: The invention is concerned with novel heterobicyclic derivatives of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, A, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
摘要翻译: 本发明涉及式(I)的新型杂双环衍生物:其中R1,R2,R3,R4,R5,R6,R7,A,X和Y如说明书和权利要求书中所定义,以及生理上可接受的 其盐和酯。 这些化合物抑制L-CPT1,可用作药物。