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9 条记录 (耗时 0.035 秒)

    Method and system for propelling and controlling displacement of a microrobot in a blood vessel
    6.
    发明授权
    Method and system for propelling and controlling displacement of a microrobot in a blood vessel 有权
    用于推动和控制血管中微型机器人的位移的方法和系统

    公开(公告)号：US07962194B2

    公开(公告)日：2011-06-14

    申请号：US10417475

    申请日：2003-04-15

    申请人： Sylvain Martel ,  Jean-Baptiste Mathieu ,  L'Hocine Yahia ,  Gilles Soulez ,  Gilles Beaudoin

    发明人： Sylvain Martel ,  Jean-Baptiste Mathieu ,  L'Hocine Yahia ,  Gilles Soulez ,  Gilles Beaudoin

    IPC分类号： A61B5/05

    CPC分类号： A61B1/00156 ,  A61B34/70 ,  A61B34/72 ,  A61B34/73

    摘要： A magnetic resonance imager (MRI) controllably propels at least one magnetic field responsive body within a subject. The MRI comprises a bore magnet producing an intense magnetic field sufficient to magnetically saturate the magnetic field responsive body. A magnetic field gradient generator is configured to apply variable magnetic gradients to at least a portion of the subject containing the magnetically-saturated body. A controller instructs the magnetic field gradient generator to acquire image data of the magnetically-saturated body within the subject and to apply a calculated magnetic gradient that will propel the magnetically-saturated body towards a target location in the subject. A tracking unit of the MRI provides position feedback information of the magnetically-saturated body within the subject.

    摘要翻译： 磁共振成像仪（MRI）可控制地推进受试者内的至少一个磁场响应体。 该MRI包括产生强磁场的孔磁体，其足以使磁场响应体磁化饱和。 磁场梯度发生器被配置为将可变磁梯度应用于包含磁饱和体的受试者的至少一部分。 控制器指示磁场梯度发生器获取被摄体内的磁饱和体的图像数据，并施加计算出的磁梯度，该磁梯度将磁饱和体推向受试者的目标位置。 MRI的跟踪单元提供受试者内的磁饱和体的位置反馈信息。

    System and method for converting adiabatic RF pulses into pseudo adiabatic RF pulses
    7.
    发明授权
    System and method for converting adiabatic RF pulses into pseudo adiabatic RF pulses 失效
    将绝热RF脉冲转换成伪绝热RF脉冲的系统和方法

    公开(公告)号：US06809518B2

    公开(公告)日：2004-10-26

    申请号：US10441563

    申请日：2003-05-20

    申请人： Gilles Beaudoin ,  Jean-Charles Côte

    发明人： Gilles Beaudoin ,  Jean-Charles Côte

    IPC分类号： G01V300

    CPC分类号： G01R33/446

    摘要： Adiabatic RF pulses are very useful in MRI when precise flip angles are needed. Unfortunately, adiabatic pulses suffer from a long application time and a high SAR. A new concept to modify the usual adiabatic pulse into a “pseudo-adiabatic” pulse having a shorter application time and lower SAR is introduced. For example, a BIR-4 of 32 ms of application time and a relative SAR of 20 will be transformed into a BIR-4-S1 of 1 ms and relative SAR of 1. The new pulse obtained stays insensitive for a large B1 range but loses its slice selectivity to become a 3D pulse. Experimental results are presented to illustrate the sensitivity to B1 and B0.

    摘要翻译： 当需要精确翻转角时，绝热RF脉冲在MRI中非常有用。 不幸的是，绝热脉冲具有长的施加时间和高的SAR。 引入了将常规绝热脉冲修改为具有较短施加时间和较低SAR的“假绝热”脉冲的新概念。 例如，32毫秒应用时间的BIR-4和20的相对SAR将被转换成1毫秒的BIR-4-S1和1的相对SAR。所获得的新脉冲对于大的B1范围而言不敏感，但是 失去其切片选择性，成为3D脉冲。 提出了实验结果，以说明对B1和B0的敏感性。

    Process and installation for continuously fractionating plant, animal or human proteins
    9.
    发明授权
    Process and installation for continuously fractionating plant, animal or human proteins 失效
    连续分选植物，动物或人类蛋白质的过程和安装

    公开(公告)号：US5043427A

    公开(公告)日：1991-08-27

    申请号：US359859

    申请日：1989-05-31

    申请人： Catherine Leberre ,  Alain Faure ,  Gilles Beaudoin ,  Brigitte Roche ,  Pierre Colinart ,  Henri Renon

    发明人： Catherine Leberre ,  Alain Faure ,  Gilles Beaudoin ,  Brigitte Roche ,  Pierre Colinart ,  Henri Renon

    IPC分类号： C07K1/30 ,  A23J1/00 ,  C07K1/14 ,  C07K14/415 ,  C07K14/435 ,  C07K14/76

    CPC分类号： A23J1/00

    摘要： This invention relates to a process for continuously fractionating plant, animal or human proteins by selective precipitation of the proteins resulting from placing a solution of proteins in contact with a precipitating agent constituted by a fatty acid of 6 to 14 carbon atoms, such as caprylic acid, is characterized in that respective deliveries of fatty acid and of the protein solution are continuously placed in contact in a mixing chamber of small volume with respect to the deliveries, creating a strong stirring in this mixing chamber; the individual deliveries of fatty acid and of protein solution are adjusted to controlled pH and temperature so as to maintain their ratio equal to a predetermined value; the mixture is then allowed to evolve during a phase of maturation so as to form a suspension; this suspension is separated into a liquid part from which are extracted the proteins having remained soluble, and a solid part containing proteins of different nature; and the parameters intervening in the process, such as delivery, pressure, temperature, pH, resistivity, are permanently monitored. The invention also relates to an installation for carrying out said process.

    摘要翻译： 本发明涉及通过将蛋白质溶液与由6〜14个碳原子的脂肪酸构成的沉淀剂接触的蛋白质的选择性沉淀来选择性沉淀植物，动物或人类蛋白质的方法，例如辛酸 其特征在于，脂肪酸和蛋白质溶液的相应输送在相对于输送的小体积的混合室中连续地接触，在该混合室中产生强烈的搅拌; 调节脂肪酸和蛋白质溶液的单独输送以控制pH和温度，以保持其比率等于预定值; 然后使混合物在成熟阶段放出，形成悬浮液; 将该悬浮液分离成液体部分，从其中提取保留可溶性的蛋白质，以及含有不同性质的蛋白质的固体部分; 并且永久地监视介入过程的参数，例如输送，压力，温度，pH，电阻率。 本发明还涉及一种用于执行所述处理的装置。