摘要:
The plastic closure of this invention is particularly, but not exclusively adapted for sealing medicament vials and other medical containers or as a collar for retaining a fluid transferset on a medical container. The plastic closure of this invention includes a generally tubular portion which surrounds the rim of the container and a free end portion which is permanently radially deformed or crimped into the neck of the container. The plastic closure of this invention is formed of a polymer, preferably a polymeric alloy or melt blend, which is sufficiently malleable to permit radial deformation, yet sufficiently rigid to retain its shape following deformation and sufficiently resistant to creep to maintain the seal between the plastic closure and the container following deformation. A preferred polymer for the plastic closure of this invention is an alloy or melt blend comprising a relatively rigid polymer such as polycarbonate and a soft malleable co-polymer such as a polyester. Where the plastic closure of this invention is used to seal a vial, for example, the closure includes a radial portion overlying the rim portion of the stopper having a central opening and a cup-shaped cap is received over the collar having retainer portions received within the central opening of the cap which may be removed by finger pressure. When the collar of this invention is used to secure a fluid transferset on a vial, the collar includes a proximate tubular portion integral with the radial portion which surrounds at least a portion of the transferset. In one embodiment, the second tubular portion surrounds the entire transferset and the open end is sealed with a peel-off seal and in another embodiment a separate cap surrounds the distal end of the transferset.
摘要:
A method of sealing a cartridge having a barrel with a polymeric closure, wherein the polymeric closure includes a tubular collar portion and an integral radial portion, The method includes disposing the tubular collar portion over the radial rim portion of the barrel to surround the reduced diameter neck portion and incrementally rolling and radially deforming the tubular collar portion adjacent its free end into the reduced diameter neck portion with a crimping tool, wherein the polymeric closure is sufficiently malleable to permit radial deformation, yet sufficiently rigid and resistant to creep to retain its shape following deformation The crimping tool or tools include an inclined surface having a gradually decreasing angles of inclination which are driven against the tubular collar portion adjacent the free end and the cartridge assembly and crimping tool are relatively rotated.
摘要:
A method of sealing a medical container such as a vial with a polymeric closure, wherein the polymeric enclosure includes a tubular collar portion and an integral radial portion, which includes disposing the tubular collar portion over the radial rim portion of the container to surround the reduced diameter neck portion and radially deforming the tubular collar portion adjacent its free end into the reduced diameter neck portion and against the adjacent radial rim portion and, wherein the polymer selected for the closure is sufficiently malleable to permit radial deformation, yet sufficiently rigid to retain its shape following deformation and sufficiently resistant to creep to maintain a seal between the plastic closure and the container following radial deformation. In the preferred embodiment of the method, the crimping tool or tools include an inclined surface having a gradually decreasing angle of inclination, which is driven against the tubular collar portion adjacent the free end and the container and vial assembly and crimping tool are relatively rotated. In the most preferred embodiment of the method of this invention, the crimping tool includes an inclined surface or surfaces, which may be separate surfaces or a continuously inclined surface, to gradually and progressively deform the tubular collar portion into the reduced diameter neck portion and against the adjacent radial rim portion in a cold forming process.
摘要:
A fluid collection or infusion set is provided. The set includes flexible tubing with a fitting attached to a proximal end and a needle assembly attached to the distal end. The needle assembly includes a needle hub and a needle cannula secured in the hub. An actuator arm extends proximally and outwardly from the needle hub and has an actuator button at its free end. The needle assembly is disposed in a barrel and can move from a distal position where the needle cannula is exposed to a proximal position where the needle cannula is shielded. A spring is disposed in the barrel for propelling the needle assembly to the proximal position. The barrel includes an actuating aperture that receives the actuator button for locking the spring in a compressed condition. Depression of the actuator button enables the spring to propel the needle assembly into its proximal shielded position.
摘要:
A method for capturing an embolus within a vessel of a patient's body includes the steps of providing a device having at least one helix made of a mesh material. The at least one helix has a plurality of turns helically arranged around a longitudinal axis. The mesh material has a plurality of pores therein wherein the pores have a size ≧120 μm. The device is placed within the vessel of the patient's body by moving the device from a collapsed state to an expanded state.
摘要:
The present invention is a syringe tip cap comprising a bottom portion, a top portion, an annular skirt extending therebetween and a plug that projects proximally from the bottom portion so as to be telescoped into the passage of a syringe tip. The plug provides means to allow air to be vented from the syringe with contacting the user. The syringe tip cap of the present invention also provides the user with an indication by tactile and visual feedback that the syringe has been vented.
摘要:
The present invention is a syringe tip cap comprising a bottom portion, a top portion, an annular skirt extending therebetween and a plug that projects proximally from the bottom portion so as to be telescoped into the passage of a syringe tip. The plug provides means to allow air to be vented from the syringe with contacting the user. The syringe tip cap of the present invention also provides the user with an indication by tactile and visual feedback that the syringe has been vented.