公开(公告)号：US20110045475A1

公开(公告)日：2011-02-24

申请号：US12830775

申请日：2010-07-06

申请人： Jean-Jacques PANTHIER ,  Giorgia Egidy ,  Xavier Sastre-Garau ,  Florence Bernex

发明人： Jean-Jacques PANTHIER ,  Giorgia Egidy ,  Xavier Sastre-Garau ,  Florence Bernex

IPC分类号： C12Q1/68 ,  C12Q1/02 ,  G01N33/53

CPC分类号： G01N33/5743 ,  G01N2333/705

摘要： The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocytic cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocytic cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein.

摘要翻译： 本发明涉及一种用于诊断哺乳动物黑素瘤的方法，包括检测所述哺乳动物的黑素细胞中RACK-1蛋白的过表达，以及从RACK-1蛋白的过表达中减少黑素瘤的存在。 本发明还涉及一种用于确定哺乳动物黑素细胞细胞的肿瘤状态的方法，包括检测黑素细胞中RACK-1蛋白的过度表达，以及所述细胞的肿瘤状态从过表达 RACK-1蛋白。