Fourier transform mass spectrometry of complex biological samples
    2.
    发明授权
    Fourier transform mass spectrometry of complex biological samples 失效
    复杂生物样品的傅立叶变换质谱

    公开(公告)号:US06680203B2

    公开(公告)日:2004-01-20

    申请号:US09735707

    申请日:2000-12-12

    IPC分类号: G01N3300

    摘要: The present invention relates to methods for high information content (HIC) analysis or screening of complex biological systems using Fourier transform mass spectrometry (FTMS). The present methods are useful for analyzing complex biological mixtures containing both high molecular weight molecules (e.g., polynucleotides, proteins, polysaccharides) and low molecular weight molecules (e.g., oligonucleotides, peptides, lipids, oligosaccharides, steroid hormones, catabolic and metabolic intermediates) permit the elucidation of molecular differences between complex biological samples, and permit the identification of biologically active molecules (e.g. therapeutically active drugs, etc.).

    摘要翻译: 本发明涉及使用傅里叶变换质谱(FTMS)的复杂生物系统的高信息含量(HIC)分析或筛选方法。 本方法可用于分析含有高分子量分子(例如多核苷酸,蛋白质,多糖)和低分子量分子(例如寡核苷酸,肽,脂质,寡糖,类固醇激素,分解代谢和代谢中间体)的复杂生物混合物 澄清复杂生物样品之间的分子差异,并允许鉴定生物活性分子(例如治疗活性药物等)。

    Eyewear, eyewear systems and associated methods for enhancing vision

    公开(公告)号:US11126014B2

    公开(公告)日:2021-09-21

    申请号:US16591154

    申请日:2019-10-02

    IPC分类号: G02B27/01 G02C11/00 G02C5/14

    摘要: Embodiments according to the present disclosure are directed to, for example, head mounted eyewear (e.g., similar in form to traditional eye glasses) that includes low light vision enhancing and/or additional vision enhancing capabilities (e.g., near-vision enhancing capabilities). For example, in some embodiments, a head mounted housing arrangement is provided that includes an eyepiece adjacent to a wearer's eye, one or more imaging devices (e.g., one or more solid state or other imagers sensitive to light, including low light levels), one or more image generator(s) operatively coupled to the imager(s) (e.g., optically coupled, in electrical communication with, or wirelessly coupled) to receive an output from the imaging device(s), and/or one or more optical elements (e.g., a combination of mirror(s) and/or lenses). The one or more optical elements may place an output of the image generator(s) into a position that is visible to the wearer's eye.

    Eyewear, eyewear systems and associated methods for enhancing vision

    公开(公告)号:US10437080B2

    公开(公告)日:2019-10-08

    申请号:US15686894

    申请日:2017-08-25

    IPC分类号: G02B27/01 G02C11/00 G02C5/14

    摘要: Embodiments according to the present disclosure are directed to, for example, head mounted eyewear (e.g., similar in form to traditional eye glasses) that includes low light vision enhancing and/or additional vision enhancing capabilities (e.g., near-vision enhancing capabilities). For example, in some embodiments, a head mounted housing arrangement is provided that includes an eyepiece adjacent to a wearer's eye, one or more imaging devices (e.g., one or more solid state or other imagers sensitive to light, including low light levels), one or more image generator(s) operatively coupled to the imager(s) (e.g., optically coupled, in electrical communication with, or wirelessly coupled) to receive an output from the imaging device(s), and/or one or more optical elements (e.g., a combination of mirror(s) and/or lenses). The one or more optical elements may place an output of the image generator(s) into a position that is visible to the wearer's eye.

    EYEWEAR, EYEWEAR SYSTEMS AND ASSOCIATED METHODS FOR ENHANCING VISION

    公开(公告)号:US20170351120A1

    公开(公告)日:2017-12-07

    申请号:US15686894

    申请日:2017-08-25

    IPC分类号: G02C11/00 G02C5/14 G02B27/01

    摘要: Embodiments according to the present disclosure are directed to, for example, head mounted eyewear (e.g., similar in form to traditional eye glasses) that includes low light vision enhancing and/or additional vision enhancing capabilities (e.g., near-vision enhancing capabilities). For example, in some embodiments, a head mounted housing arrangement is provided that includes an eyepiece adjacent to a wearer's eye, one or more imaging devices (e.g., one or more solid state or other imagers sensitive to light, including low light levels), one or more image generator(s) operatively coupled to the imager(s) (e.g., optically coupled, in electrical communication with, or wirelessly coupled) to receive an output from the imaging device(s), and/or one or more optical elements (e.g., a combination of mirror(s) and/or lenses). The one or more optical elements may place an output of the image generator(s) into a position that is visible to the wearer's eye.

    Eyewear, Eyewear Systems and Associated Methods for Enhancing Vision

    公开(公告)号:US20200033640A1

    公开(公告)日:2020-01-30

    申请号:US16591154

    申请日:2019-10-02

    IPC分类号: G02C11/00 G02B27/01 G02C5/14

    摘要: Embodiments according to the present disclosure are directed to, for example, head mounted eyewear (e.g., similar in form to traditional eye glasses) that includes low light vision enhancing and/or additional vision enhancing capabilities (e.g., near-vision enhancing capabilities). For example, in some embodiments, a head mounted housing arrangement is provided that includes an eyepiece adjacent to a wearer's eye, one or more imaging devices (e.g., one or more solid state or other imagers sensitive to light, including low light levels), one or more image generator(s) operatively coupled to the imager(s) (e.g., optically coupled, in electrical communication with, or wirelessly coupled) to receive an output from the imaging device(s), and/or one or more optical elements (e.g., a combination of mirror(s) and/or lenses). The one or more optical elements may place an output of the image generator(s) into a position that is visible to the wearer's eye.