公开(公告)号：US20090076495A2

公开(公告)日：2009-03-19

申请号：US11617656

申请日：2006-12-28

申请人： Jeremy Dando ,  Timothy Curran ,  Todd Stangenes

发明人： Jeremy Dando ,  Timothy Curran ,  Todd Stangenes

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2018/00642 ,  A61B2018/00797 ,  A61B2018/00839 ,  A61B2018/1472

摘要： A catheter is designed with a virtual electrode structure for creating a linear lesion. The catheter includes a sensor array that measures temperatures of adjacent tissue along the length of the virtual electrode section. The sensors in the sensor array include a conductive material that is substantially coated with an electrically and thermally insulating material. An aperture is formed in the insulating coating to expose an area of the conductive material. Leads are coupled with each sensor and are connected at their opposite, proximal ends with a discrimination circuit. The circuit processes the signals induced in the sensors to output a single temperature measurement, for example, the highest temperature, the lowest temperature, or the average temperature. The sensors also measure cardiac electrical activity and the leads are further connected to an electrocardiograph monitor to determine the efficacy of treatment.

摘要翻译： 导管设计有用于产生线性损伤的虚拟电极结构。 导管包括传感器阵列，其测量沿着虚拟电极部分的长度的相邻组织的温度。 传感器阵列中的传感器包括基本上涂覆有电绝热材料的导电材料。 在绝缘涂层中形成孔以暴露导电材料的区域。 引线与每个传感器耦合，并且在其相对的近端处与鉴别电路连接。 电路处理在传感器中感应的信号，以输出单个温度测量，例如最高温度，最低温度或平均温度。 传感器还测量心脏电活动，并且引线进一步连接到心电图仪监测器以确定治疗的功效。

公开(公告)号：US20080071267A1

公开(公告)日：2008-03-20

申请号：US11948362

申请日：2007-11-30

申请人： Huisun Wang ,  Jeremy Dando ,  Harry Puryear

发明人： Huisun Wang ,  Jeremy Dando ,  Harry Puryear

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2017/00084 ,  A61B2018/00577 ,  A61B2218/002

摘要： Embodiments of the present invention provide an irrigated catheter having irrigation fluid directed at target areas where coagulation is more likely to occur so as to minimize blood coagulation and the associated problems. In one embodiment, an irrigated ablation electrode assembly for use with an irrigated catheter device comprises a proximal member having at least one passageway for a fluid with an outlet disposed at an external surface of the proximal member; and a distal member connected with the proximal member and having an external surface. The distal member includes an electrode. The external surface of the proximal member and the external surface of the distal member meet at an intersection. The at least one passageway of the proximal member is configured to direct a fluid flow through the outlet toward a region adjacent the intersection.

摘要翻译： 本发明的实施方案提供了一种具有冲洗流体的灌溉导管，该冲洗流体被引导到更可能发生凝结的目标区域，从而使血液凝固和相关问题最小化。 在一个实施例中，一种与灌溉导管装置一起使用的灌溉消融电极组件包括近端构件，其具有用于流体的至少一个通道，其中出口设置在近端构件的外表面处; 以及与所述近端构件连接并具有外表面的远侧构件。 远侧构件包括电极。 近端构件的外表面和远端构件的外表面在相交处相交。 近端构件的至少一个通道构造成将流体流动引导通过邻近交叉点的区域。

公开(公告)号：US09579148B2

公开(公告)日：2017-02-28

申请号：US11939206

申请日：2007-11-13

申请人： Huisun Wang ,  Jeremy Dando

发明人： Huisun Wang ,  Jeremy Dando

IPC分类号： A61B18/14 ,  A61B18/00

CPC分类号： A61B18/1492 ,  A61B2018/00029 ,  A61B2218/002

摘要： The present invention relates to ablation electrode assemblies. The present invention further relates to an irrigated ablation electrode assembly that includes a recessed portion that can improve fluid flow around the irrigated ablation electrode. The electrode includes an outer body portion having an outer surface, and an inner cavity defined within the outer body portion. The electrode further includes at least one passageway for fluid flow from the inner cavity to the outer surface of the body of the electrode. The passageway further defines an outlet on the external surface of the electrode, therein allowing the fluid to flow on and/or around the electrode surface. The outer surface of the electrode further includes a recessed portion. The outlet of the passageway is disposed at least partially within the recessed portion. The fluid that exits the passageway may flow within the recessed portion to improve irrigation of the electrode.

摘要翻译： 本发明涉及消融电极组件。 本发明还涉及一种灌溉消融电极组件，其包括可以改善灌洗消融电极周围的流体流动的凹陷部分。 电极包括具有外表面的外主体部分和限定在外主体部分内的内腔。 电极还包括至少一个通道，用于流体从内腔流到电极主体的外表面。 通道还限定了电极的外表面上的出口，其中允许流体在电极表面上和/或周围流动。 电极的外表面还包括凹部。 通道的出口至少部​​分地设置在凹部内。 离开通道的流体可以在凹部内流动，以改善电极的冲洗。

公开(公告)号：US08128620B2

公开(公告)日：2012-03-06

申请号：US11939195

申请日：2007-11-13

申请人： Huisun Wang ,  Jeremy Dando

发明人： Huisun Wang ,  Jeremy Dando

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2018/00029 ,  A61B2218/002

摘要： The present invention relates to improved ablation electrodes and catheter assemblies, as well as methods useful in conjunction with irrigated ablation catheters. Embodiments of the present invention further relate to an irrigated catheter having irrigation fluid directed at target areas where coagulation is more likely to occur to help minimize blood coagulation and the associated problems. The present invention further relates to an ablation electrode having an outer body with a proximal portion and a distal portion an inner cavity and at least one passageway that extends to an opening on the outer surface of the electrode, wherein the passageway is directed towards the proximal portion and/or proximal end of the electrode forming an acute angle with a longitudinal axis of the electrode.

摘要翻译： 本发明涉及改进的消融电极和导管组件以及与冲洗消融导管结合使用的方法。 本发明的实施例还涉及一种具有冲洗流体的灌溉导管，该冲洗流体指向更可能发生凝血的目标区域，以帮助最小化凝血和相关问题。 本发明还涉及一种具有外主体的消融电极，该外体具有近端部分和远端部分，其具有内腔和至少一个延伸到电极外表面上的开口的通道，其中该通道朝向近端 电极的部分和/或近端与电极的纵向轴线形成锐角。

公开(公告)号：US20070219551A1

公开(公告)日：2007-09-20

申请号：US11752755

申请日：2007-05-23

申请人： Kirk Honour ,  Michael Johnson ,  Gabriel Mouchawar ,  Jeremy Dando ,  Christine Byam

发明人： Kirk Honour ,  Michael Johnson ,  Gabriel Mouchawar ,  Jeremy Dando ,  Christine Byam

IPC分类号： A61B18/18 ,  A61N1/00

CPC分类号： A61B5/0422 ,  A61B5/6852 ,  A61B18/1492 ,  A61B2018/00839 ,  A61B2562/227 ,  A61N1/05

摘要： A catheter or lead having a flexible printed circuit for conveying signals and/or energy. Each trace may be in electrical connection with one or more external electrical contacts. More specifically, each trace is typically electrically connected to a single contact. The traces and contacts may assist in diagnosis and/or detection of bio-electrical signals emitted by organs, and may transmit such signals to a connector or diagnostic device affixed to the catheter. The external electrical contacts may detect bioelectric energy or may deliver electrical or thermal energy to a target site.

摘要翻译： 具有用于传送信号和/或能量的柔性印刷电路的导管或导线。 每个迹线可以与一个或多个外部电触点电连接。 更具体地，每个迹线通常电连接到单个接触。 迹线和触点可以有助于诊断和/或检测由器官发射的生物电信号，并且可以将这些信号传输到固定到导管的连接器或诊断装置。 外部电触点可以检测生物电能或者可以将电能或热能传递到目标部位。

公开(公告)号：US20070005053A1

公开(公告)日：2007-01-04

申请号：US11172647

申请日：2005-06-30

申请人： Jeremy Dando

发明人： Jeremy Dando

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2018/00083 ,  A61B2018/00375

摘要： An array of ring electrodes or a wire electrode is mounted about the outside surface of the distal end of the ablation catheter. Substantially all of the outer surface of each ring or wire electrode is covered by an electrically insulating coating. The insulating surface coating on each ring defines a contoured opening in the insulating surface coating that exposes the conductive band or wire beneath. An array of contoured openings are formed along a wire electrode. The insulating coating mitigates potential edge effects that create hot spots and can result in unwanted tissue damage during an ablation procedure.

摘要翻译： 围绕消融导管的远端的外表面安装环形电极或线电极的阵列。 每个环或线电极的基本上所有的外表面被电绝缘涂层覆盖。 每个环上的绝缘表面涂层在绝缘表面涂层中限定了暴露下面的导电带或线的成形开口。 沿着线电极形成轮廓开口阵列。 绝缘涂层减轻了产生热点的潜在边缘效应，并可能在消融过程中导致不想要的组织损伤。

公开(公告)号：US20090125017A1

公开(公告)日：2009-05-14

申请号：US11939206

申请日：2007-11-13

申请人： Huisun Wang ,  Jeremy Dando

发明人： Huisun Wang ,  Jeremy Dando

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2018/00029 ,  A61B2218/002

摘要： The present invention relates to ablation electrode assemblies. The present invention further relates to an irrigated ablation electrode assembly that includes a recessed portion that can improve fluid flow around the irrigated ablation electrode. The electrode includes an outer body portion having an outer surface, and an inner cavity defined within the outer body portion. The electrode further includes at least one passageway for fluid flow from the inner cavity to the outer surface of the body of the electrode. The passageway further defines an outlet on the external surface of the electrode, therein allowing the fluid to flow on and/or around the electrode surface. The outer surface of the electrode further includes a recessed portion. The outlet of the passageway is disposed at least partially within the recessed portion. The fluid that exits the passageway may flow within the recessed portion to improve irrigation of the electrode.

摘要翻译： 本发明涉及消融电极组件。 本发明还涉及一种灌溉消融电极组件，其包括可以改善灌洗消融电极周围的流体流动的凹陷部分。 电极包括具有外表面的外主体部分和限定在外主体部分内的内腔。 电极还包括至少一个通道，用于流体从内腔流到电极主体的外表面。 通道还限定了电极的外表面上的出口，其中允许流体在电极表面上和/或周围流动。 电极的外表面还包括凹部。 通道的出口至少部​​分地设置在凹部内。 离开通道的流体可以在凹部内流动，以改善电极的冲洗。

公开(公告)号：US20080091193A1

公开(公告)日：2008-04-17

申请号：US11953615

申请日：2007-12-10

申请人： James Kauphusman ,  Huisun Wang ,  Jeremy Dando ,  Harry Puryear

发明人： James Kauphusman ,  Huisun Wang ,  Jeremy Dando ,  Harry Puryear

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2034/2051 ,  A61B2218/002

摘要： Embodiments of the present invention provide an irrigated ablation electrode assembly for use with an irrigated catheter device comprises at least one passageway for a fluid with an outlet disposed at an external surface of the electrode assembly; a permanent magnet; a shield separating the permanent magnet from the at least one passageway and from an exterior, the shield being substantially less oxidizable than the permanent magnet; and an electrode having an external electrode surface. A catheter guidance control and imaging system drives the permanent magnet to guide and control the catheter tip. In specific embodiments, the irrigation fluid flow paths through the electrode assembly are thermally insulated from the electrode and temperature sensor. The irrigation fluid is directed at target areas where coagulation is more likely to occur. One or more monitoring electrodes are provided for mapping or other monitoring functions.

摘要翻译： 本发明的实施例提供了一种与灌溉导管装置一起使用的灌溉消融电极组件，其包括用于流体的至少一个通道，其中出口设置在电极组件的外表面处; 永久磁铁 将所述永磁体与所述至少一个通道和外部分离的屏蔽件，所述屏蔽件比所述永磁体基本上更不可氧化; 和具有外部电极表面的电极。 导管引导控制和成像系统驱动永磁体引导和控制导管尖端。 在具体实施例中，穿过电极组件的冲洗流体流动路径与电极和温度传感器热绝缘。 冲洗液被引导到更可能发生凝结的目标区域。 提供一个或多个监视电极用于映射或其他监视功能。

公开(公告)号：US20060111708A1

公开(公告)日：2006-05-25

申请号：US11328565

申请日：2006-01-10

申请人： Guy Vanney ,  Jeremy Dando ,  Joshua Dudney

发明人： Guy Vanney ,  Jeremy Dando ,  Joshua Dudney

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00041 ,  A61B2018/00375 ,  A61B2018/1472 ,  C08L2201/12

摘要： An ablation catheter having a catheter shaft and a virtual electrode, the virtual electrode comprising portholes through an outer peripheral wall of the catheter shaft and a metal electrode, the catheter being used for treatment of cardiac arrhythmia, for example, atrial fibrillation, by electrically isolating a vessel, such as a pulmonary vein, from a chamber, such as the left atrium. The catheter shaft includes a proximal portion and a distal portion. The distal portion includes an active region, which is either a looped structure transverse to the longitudinal axis of the catheter shaft, or a linear structure that extends parallel to the longitudinal axis of the catheter shaft. During use, the active region is directed into contact with, for example, the wall of a pulmonary vein. Upon energization, the virtual electrode creates a continuous lesion on an inner wall of the pulmonary vein, thereby electrically isolating the pulmonary vein from the left atrium.

公开(公告)号：US20060052773A1

公开(公告)日：2006-03-09

申请号：US11264649

申请日：2005-11-01

申请人： Guy Vanney ,  Jeremy Dando

发明人： Guy Vanney ,  Jeremy Dando

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00065 ,  A61B2018/00375 ,  A61B2018/1472 ,  C08L2201/12

摘要： An ablation catheter used for treatment of, for example, atrial fibrillation by electrically isolating a vessel, such as a pulmonary vein, from a chamber, such as the left atrium. The ablation catheter has a virtual electrode and a catheter shaft. The virtual electrode comprises a porous conductor. The catheter shaft includes a proximal portion and a distal portion. The distal portion includes an active region, which is either a looped structure transverse to the longitudinal axis of the catheter shaft, or a linear structure that extends parallel to the longitudinal axis of the catheter shaft. During use, the active region is directed into contact with, for example, the wall of a pulmonary vein and, upon energization, the virtual electrode creates a continuous lesion at or near the ostium of the pulmonary vein, thereby electrically isolating the pulmonary vein from the left atrium.

摘要翻译： 一种消融导管，用于通过从腔室（例如左心房）电隔离血管（例如肺静脉）来治疗例如心房颤动。 消融导管具有虚拟电极和导管轴。 虚拟电极包括多孔导体。 导管轴包括近端部分和远端部分。 远侧部分包括活动区域，其是横向于导管轴的纵向轴线的环形结构，或者平行于导管轴的纵向轴线延伸的线性结构。 在使用期间，有源区域被引导与例如肺静脉的壁接触，并且在通电时，虚拟电极在肺静脉的口处或其附近产生连续的病变，从而将肺静脉与 左心房。