TARGETED CONTRAST AGENTS AND USES THEREOF
    4.
    发明申请
    TARGETED CONTRAST AGENTS AND USES THEREOF 审中-公开
    具有针对性的对照代理及其用途

    公开(公告)号:US20140065075A1

    公开(公告)日:2014-03-06

    申请号:US14112349

    申请日:2012-04-17

    IPC分类号: A61K49/10 A61K49/08

    摘要: Described herein is a contrast agent for administration to a subject. The contrast agent includes a targeting portion that includes an unchelated aminocarboxylate functional group; a metal ion bound to a metal-complexable portion; and a linker joining the targeting portion and the metal-complexable portion of the contrast agent. The portion that is not bound to a metal ion is for binding to necrotic tissue in the subject.

    摘要翻译: 本文描述了用于给予受试者的造影剂。 造影剂包括靶向部分,其包含未切割的氨基羧酸酯官能团; 与金属络合部分结合的金属离子; 以及将造影剂的靶向部分和金属可络合部分连接的接头。 不结合金属离子的部分用于结合受试者的坏死组织。

    Imidazole-5-carboxylic acid compounds
    7.
    发明授权
    Imidazole-5-carboxylic acid compounds 失效
    咪唑-5-羧酸化合物

    公开(公告)号:US5932741A

    公开(公告)日:1999-08-03

    申请号:US106782

    申请日:1998-06-29

    IPC分类号: C07D405/06 A61K31/415

    CPC分类号: C07D405/06

    摘要: The invention relates to the use and the products of formula (I): ##STR1## in which: R.sub.1 =represents hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, formyl, cycloalkyl, optionally interrupted by heteroatoms,R.sub.2, R.sub.3 represent in particular halogen, mercapto, acyl, carboxy, nitro, cyano, amino, carbamoyl, R.sub.4, --OR.sub.4 with R.sub.4 representing in particular hydrogen, alkyl, alkenyl, alkynyl, acyl, amino, --(CH.sub.2).sub.m1 --S(o).sub.m2 --X--R.sub.10 with m1=0 to 4, m2=0 to 2, X represents a single bond or --NH--, --NH--CO--, --NH--CO--NH--, and R.sub.10 represents alkyl, alkenyl or aryl,and Y represents optionally substituted aryl,these products being in all the isomer forms and the salts, as medicaments.

    摘要翻译: 本发明涉及式(I)的用途和产物:其中:R1 =代表羟基,烷基,烯基,炔基,烷氧基,烷硫基,甲酰基,环烷基,任选被杂原子中断,R 2,R 3特别表示卤素, 巯基,酰基,羧基,硝基,氰基,氨基,氨基甲酰基,R4,-OR4,其中R4代表特别是氢,烷基,烯基,炔基,酰基,氨基, - (CH2)m1-S(o)m2-X-R10 m1 = 0〜4,m2 = 0〜2,X表示单键或-NH-,-NH-CO-,-NH-CO-NH-,R10表示烷基,烯基或芳基,Y表示 取代的芳基,这些产物是所有异构体形式和盐,作为药物。

    DRIVING METHOD FOR COMMON ELECTRODES, CIRCUIT AND LIQUID CRYSTAL DISPLAY THEREOF
    10.
    发明申请
    DRIVING METHOD FOR COMMON ELECTRODES, CIRCUIT AND LIQUID CRYSTAL DISPLAY THEREOF 有权
    用于通用电极的驱动方法,电路和液晶显示器

    公开(公告)号:US20120092312A1

    公开(公告)日:2012-04-19

    申请号:US13376495

    申请日:2011-04-18

    IPC分类号: G09G5/00

    摘要: A common electrode driving method, comprises: generating a first common electrode signal to be applied to a storage electrode line of each row of pixels on an array substrate, and a second common electrode signal to be applied to a common electrode forming a liquid crystal capacitance with pixel electrodes of each row of pixels on the array substrate, the first common electrode signal being opposite to a gate signal for gate electrodes applied to the corresponding row of pixels in terms of transition timing; and inputting the first common electrode signal to each row of pixels, and inputting the second common electrode signal to the common electrode.

    摘要翻译: 公共电极驱动方法包括:产生施加到阵列基板上的每行像素的存储电极线的第一公共电极信号和施加到形成液晶电容的公共电极的第二公共电极信号 与阵列基板上的每行像素的像素电极相对,第一公共电极信号与用于转换时序的相应像素行的门电极的栅极信号相反; 以及将第一公共电极信号输入到每行像素,并将第二公共电极信号输入到公共电极。